Anthony Yachnis, M.D.

Anthony T Yachnis, M.D. - Research & Publications

(352) 627-9240

Publications

Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis
Laboratory Investigation
2019

Sca8 Ran Polyser Protein Preferentially Accumulates in White Matter Regions and Is Regulated By Eif3F
The EMBO journal
2018

An Incidental Diffuse Midline Glioma Found at Autopsy
Journal of Forensic Sciences
2018

Ran Translation Regulated By Muscleblind Proteins in Myotonic Dystrophy Type 2
Neuron
2017

Pathology Residents Comprise Inspection Team for a CAP Self-Inspection
Academic Pathology
2017

Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma
Clinical Cancer Research
2017

A Pathologist's Perspective on Induced Pluripotent Stem Cells
Laboratory Investigation
2017

5 Year Expression and Neutrophil Defect Repair After Gene Therapy in Alpha-1 Antitrypsin Deficiency
Molecular Therapy
2017

Post-mortem Findings in Huntington's Deep Brain Stimulation: A Moving Target Due to Atrophy
Tremor and Other Hyperkinetic Movements
2016

Optic Nerve Pilomyxoid Astrocytoma in a Patient With Noonan Syndrome

2015

Murine a Beta Over-Production Produces Diffuse and Compact Alzheimer-Type Amyloid Deposits
Acta Neuropathologica Communications
2015

Disseminated Intraventricular Glioneuronal Tumors: New Entity Or Variation of a Theme?

2015

59 Year old female with cerebellopontine angle hemorrhage
Brain Pathology
2015

Pediatric Brainstem Tumors With Features of Angiocentric Glioma: Report of Two Cases

2014

Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study
Plos One
2014

Inadvertent Intrathecal Vincristine Administration With Widespread Axonal Injury Demonstrated By App Immunohistochemistry

2014

Hemangioblastoma in the lung: metastatic or primary lesions?
Case Reports in Pathology
2014

CNS intraoperative consultation: a survival guide for non-neuropathologists
Methods in Molecular Biology
2014

An Independent Elderly Woman With Rapid Onset of Coma
Jama Neurology
2014

Vertebral Brown Tumors Causing Neurologic Compromise
World Neurosurgery
2013

Strong Zeb1 Immunoreactivity in Idh1-Positive Infiltrating Gliomas: a Possible Link Between Tumorigenic Pathways?

2013

Purkinje Cell Loss Is the Major Brain Pathology of Spinocerebellar Ataxia Type 10
Journal of Neurology Neurosurgery and Psychiatry
2013

Human Treg Responses Allow Sustained Recombinant Adeno-Associated Virus-Mediated Transgene Expression

2013

Chondroitin Sulfate Proteoglycans Potently Inhibit Invasion and Serve as a Central Organizer of the Brain Tumor Microenvironment
Journal of Neuroscience
2013

Anticancer Effects of Niclosamide in Human Glioblastoma
Clinical Cancer Research
2013

Postmortem Observation of Collagenous Lead Tip Region Fibrosis as a Rare Complication of Dbs
Movement Disorders
2012

Neuropathologic Findings in Myotonic Dystrophy Type 2

2012

Neurogenic Potential of Progenitor Cells Isolated From Postmortem Human Parkinsonian Brains
Brain Research
2012

Mutated Isocitrate Dehydrogenase-1 (Idh-1) Immunoreactive Glioblastoma With Idh-1 Negative `Pnet-Like' Elements

2012

Meningiomas in Pregnancy: a Clinicopathologic Study of 17 Cases
Neurosurgery
2012

Gliosis versus glioma?: don't grade until you know
Advances in Anatomic Pathology
2012

Deep Brain Stimulation Response in Pathologically Confirmed Cases of Multiple System Atrophy
Parkinsonism & Related Disorders
2012

Alpha-1 Antitrypsin (Aat) Expression 1 Year After Im Administration of Raav1-Cb-Haat in a Phase 2 Clinical Trial
Molecular Therapy
2012

The Neuropathology of Mucopolysaccharidosis Type Vii (Sly Disease): a Case Report and Review of the Literature

2011

The National Dbs Brain Tissue Network Pilot Study: Need for More Tissue and More Standardization
Cell and Tissue Banking
2011

The Central Nervous System Solitary Fibrous Tumor: a Review of Clinical, Imaging and Pathologic Findings Among All Reported Cases From 1996 To 2010
Clinical Neurology and Neurosurgery
2011

Phase 2 Clinical Trial of a Recombinant Adeno-Associated Viral Vector Expressing Alpha(1)-Antitrypsin: Interim Results
Human Gene Therapy
2011

Collagenous Fibrosis: a Rare Tissue Reaction of Deep Brain Stimulation (Dbs)

2011

Atypical Rasmussen's Encephalitis Treated With Temporal Lobectomy
Journal of Clinical Neuroscience
2011

A Pilot Study of Human Brain Tissue Post-Magnetic Resonance Imaging: Information From the National Deep Brain Stimulation Brain Tissue Network (Dbs-Btn)

2011

Unexpectedly Long-Term Control of Recurrent Gliomatosis Cerebri With Capecitabine: a Possible Molecular Explanation
Neuro-Oncology
2010

Meningiomas Resected During Pregnancy: a Clinicopathologic Study of Eight Patients
Neuro-Oncology
2010

Glioma Diagnosis: Immunohistochemistry and Beyond
Advances in Anatomic Pathology
2010

Fragile X Dementia Parkinsonism Syndrome (Fxdps)
Cognitive and Behavioral Neurology
2010

Atpyical Presentation and Morbidity With Rituximab in Diffuse Large B-Cell Lymphoma Infiltrating the Spine
Neuro-Oncology
2010

Radiographic and Pathologic Findings in An Atypical Brainstem Variant of Reversible Posterior Leukoencephalopathy Syndrome
The Neurologist
2009

Postmortem Interval Alters the Water Relaxation and Diffusion Properties of Rat Nervous Tissue - Implications for Mri Studies of Human Autopsy Samples

2009

Hematopoietic- and Neurologic-Expressed Sequence 1 Expression in the Murine Gl261 and High-Grade Human Gliomas
Pathology and Oncology Research
2009

A Posterior Fossa Embryonal Tumor in a 4-Year-Old Male With Features of Atrt But Without Ini1 Mutation

2009

The Publishing Game: Reflections of An Editorial Team
Modern Pathology
2008

Surgical Neuropathology Update - a Review of Changes Introduced By the Who Classification of Tumours of the Central Nervous System, 4Th Edition
Archives of Pathology & Laboratory Medicine
2008

Structure-Based Jaz Ligand-Ji and Its Analogues Show Strong Cytotoxic Effects On Glioma Cells in Vitro - a New Class of Glioma Therapy Drugs?

2008

Protocol for the Examination of Specimens From Patients With Tumors of the Brain/Spinal Cord
Archives of Pathology & Laboratory Medicine
2008

Neurotropic Melanoma of the Trigeminal Nerve: a Case of Atypical Facial Pain
Journal of Oral and Maxillofacial Surgery
2008

Invasion Suppressor Cystatin E/M (Cst6): High-Level Cell Type-Specific Expression in Normal Brain and Epigenetic Silencing in Gliomas
Modern Pathology
2008

Can Standard Magnetic Resonance Imaging Reliably Distinguish Recurrent Tumor From Radiation Necrosis After Radiosurgery for Brain Metastases? a Radiographic-Pathological Study
Neurosurgery
2008

Plexiform-like neurofibromas develop in the mouse by intraneural xenograft of an NF1 tumor-derived Schwann cell line.

2007

In vitro studies of steroid hormones in neurofibromatosis 1 tumors and Schwann cells
Molecular Carcinogenesis
2007

Diffusion tensor microscopy indicates the cytoarchitectural basis for diffusion anisotropy in the human hippocampus.

2007

An orthotopic xenograft model of intraneural NF1 MPNST suggests a potential association between steroid hormones and tumor cell proliferation.
Modern Pathology
2007

Pontine atypical neurocytoma: case report
Neurosurgery
2006

Brainstem stereotactic biopsy sampling in children.
Journal of Neurosurgery-Spine
2006

Paraneoplastic chorea with leukoencephalopathy presenting with obsessive-compulsive and behavioral disorder.
Movement Disorders
2005

Neonatal hypothalamic hamartoma: a differentiating nonlethal hamartoblastoma.
Journal of Neurosurgery-Spine
2005

Secondary leptomeningeal sarcomatosis.
Archives of Pathology & Laboratory Medicine
2004

Pituicytoma: report of two cases and clues regarding histogenesis.
Neurosurgery
2004

Rhombencephalosynapsis with massive hydrocephalus: case report and pathogenetic considerations.
Acta Neuropathologica
2002

Ex vivo high-resolution magnetic resonance imaging of the brain in Joubert's syndrome.
Journal of Child Neurology
2002

Cortical dysgenesis and epilepsy.
Neuroscientist
2002

Tumorigenic properties of neurofibromin-deficient neurofibroma Schwann cells.
American Journal of Pathology
2001

Neuropathology of Joubert syndrome.
Journal of Child Neurology
1999

Molar tooth sign in Joubert syndrome: clinical, radiologic, and pathologic significance.
Journal of Child Neurology
1999

Cerebellar and brainstem development: an overview in relation to Joubert syndrome.
Journal of Child Neurology
1999

Research Interests

Neuropathology, surgical and eye pathology, and pediatric neuropathology