Anthony T Yachnis, M.D.

Publications

Neuropathology of Alzheimer's Disease.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
2022

Central Nervous System Tumor Classification: An Update on the Integration of Tumor Genetics.
Hematology/oncology clinics of North America
2022

A Pioneer of Pediatric Brain Tumors: Dr. Lucy Rorke-Adams.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
2022

Upfront Adjuvant Immunotherapy of Replication Repair-Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach.
JCO precision oncology
2021

Orbital metastasis of squamous cell cervical cancer: A case report and review of literature.
Gynecologic oncology reports
2021

Inflammatory myofibroblastic tumor masquerading as an anterior choroidal artery fusiform aneurysm.
Surgical neurology international
2021

Case Studies in Neuroscience: Neuropathology and diaphragm dysfunction in ventilatory failure from late-onset Pompe disease.
Journal of neurophysiology
2021

Prominent amyloid plaque pathology and cerebral amyloid angiopathy in APP V717I (London) carrier - phenotypic variability in autosomal dominant Alzheimer's disease.
Acta neuropathologica communications
2020

Pediatric pathology all grown up - An interesting case of adult tethered spinal cord.
Surgical neurology international
2020

Novel monoclonal antibodies targeting the RRM2 domain of human TDP-43 protein.
Neuroscience letters
2020

Generation and Characterization of Novel Monoclonal Antibodies Targeting p62/sequestosome-1 Across Human Neurodegenerative Diseases
Journal of Neuropathology and Experimental Neurology
2020

An Unusual Cause of Intracerebral Hemorrhage: Clinical Pearls Regarding Primary Angiitis of the Central Nervous System.
Neurological sciences and neurosurgery
2020

Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression.
Acta neuropathologica communications
2019

Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology.
Acta neuropathologica communications
2019

Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis.
Laboratory investigation; a journal of technical methods and pathology
2019

Comparative analyses of the in vivo induction and transmission of -synuclein pathology in transgenic mice by MSA brain lysate and recombinant -synuclein fibrils
Acta Neuropathologica Communications
2019

SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.
The EMBO journal
2018

Deep Brain Stimulation associated gliosis: A post-mortem study.
Parkinsonism & related disorders
2018

An Incidental Diffuse Midline Glioma Found at Autopsy.
Journal of forensic sciences
2018

RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.
Neuron
2017

Pathology Residents Comprise Inspection Team for a CAP Self-Inspection.
Academic pathology
2017

Functional Subclone Profiling for Prediction of Treatment-Induced Intratumor Population Shifts and Discovery of Rational Drug Combinations in Human Glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
2017

Eleven Month Progression-Free Survival on Vemurafenib Monotherapy in a Patient With Recurrent and Metastatic BRAF V600E-Mutated Glioblastoma WHO Grade 4.
JCO precision oncology
2017

A pathologist's perspective on induced pluripotent stem cells.
Laboratory investigation; a journal of technical methods and pathology
2017

5 Year Expression and Neutrophil Defect Repair after Gene Therapy in Alpha-1 Antitrypsin Deficiency.
Molecular therapy : the journal of the American Society of Gene Therapy
2017

Second report of a Nocardia beijingensis infection in the United States: nodular scleritis with in vitro imipenem resistance.
Digital journal of ophthalmology : DJO
2016

Post-mortem Findings in Huntington's Deep Brain Stimulation: A Moving Target Due to Atrophy.
Tremor and other hyperkinetic movements (New York, N.Y.)
2016

C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD.
Neuron
2016

Bilateral internal auditory canal gangliogliomas mimicking neurofibromatosis Type II.
Surgical neurology international
2016

Serpin treatment suppresses inflammatory vascular lesions in temporal artery implants (TAI) from patients with giant cell arteritis.
PloS one
2015

RAN Translation in Huntington Disease.
Neuron
2015

Optic nerve pilomyxoid astrocytoma in a patient with Noonan syndrome.
Pediatric blood & cancer
2015

Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits.
Acta neuropathologica communications
2015

Disseminated Intraventricular Glioneuronal Tumors: New Entity Or Variation of a Theme?
Journal of Neuropathology and Experimental Neurology
2015

59 Year old female with cerebellopontine angle hemorrhage.
Brain pathology (Zurich, Switzerland)
2015

Pediatric Brainstem Tumors With Features of Angiocentric Glioma: Report of Two Cases
Journal of Neuropathology and Experimental Neurology
2014

Increased precursor cell proliferation after deep brain stimulation for Parkinson's disease: a human study.
PloS one
2014

Inadvertent Intrathecal Vincristine Administration With Widespread Axonal Injury Demonstrated By App Immunohistochemistry
Journal of Neuropathology and Experimental Neurology
2014

Hemangioblastoma in the lung: metastatic or primary lesions?
Case reports in pathology
2014

CNS intraoperative consultation: a survival guide for non-neuropathologists.
Methods in molecular biology (Clifton, N.J.)
2014

An independent elderly woman with rapid onset of coma.
JAMA neurology
2014

Vertebral brown tumors causing neurologic compromise.
World neurosurgery
2013

Strong Zeb1 Immunoreactivity in Idh1-Positive Infiltrating Gliomas: a Possible Link Between Tumorigenic Pathways?
Journal of Neuropathology and Experimental Neurology
2013

Purkinje cell loss is the major brain pathology of spinocerebellar ataxia type 10.
Journal of neurology, neurosurgery, and psychiatry
2013

Human Treg responses allow sustained recombinant adeno-associated virus-mediated transgene expression.
The Journal of clinical investigation
2013

Chondroitin sulfate proteoglycans potently inhibit invasion and serve as a central organizer of the brain tumor microenvironment.
The Journal of neuroscience : the official journal of the Society for Neuroscience
2013

Anticancer effects of niclosamide in human glioblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
2013

Takayasu's arteritis: Is it a reversible disease? Case Report and Literature Review.
Surgical neurology international
2012

Postmortem observation of collagenous lead tip region fibrosis as a rare complication of DBS.
Movement disorders : official journal of the Movement Disorder Society
2012

Neuropathologic Findings in Myotonic Dystrophy Type 2
Journal of Neuropathology and Experimental Neurology
2012

Neurogenic potential of progenitor cells isolated from postmortem human Parkinsonian brains.
Brain research
2012

Mutated Isocitrate Dehydrogenase-1 (Idh-1) Immunoreactive Glioblastoma With Idh-1 Negative `Pnet-Like' Elements
Journal of Neuropathology and Experimental Neurology
2012

Meningiomas in pregnancy: a clinicopathologic study of 17 cases.
Neurosurgery
2012

Gliosis versus glioma?: don't grade until you know.
Advances in anatomic pathology
2012

Deep brain stimulation response in pathologically confirmed cases of multiple system atrophy.
Parkinsonism & related disorders
2012

Alpha-1 Antitrypsin (Aat) Expression 1 Year After Im Administration of Raav1-Cb-Haat in a Phase 2 Clinical Trial
Molecular Therapy
2012

The national DBS brain tissue network pilot study: need for more tissue and more standardization.
Cell and tissue banking
2011

The central nervous system solitary fibrous tumor: a review of clinical, imaging and pathologic findings among all reported cases from 1996 to 2010.
Clinical neurology and neurosurgery
2011

The Neuropathology of Mucopolysaccharidosis Type Vii (Sly Disease): a Case Report and Review of the Literature
Journal of Neuropathology and Experimental Neurology
2011

Phase 2 clinical trial of a recombinant adeno-associated viral vector expressing α1-antitrypsin: interim results.
Human gene therapy
2011

Collagenous Fibrosis: a Rare Tissue Reaction of Deep Brain Stimulation (Dbs)
Journal of Neuropathology and Experimental Neurology
2011

Atypical Rasmussen's encephalitis treated with temporal lobectomy.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia
2011

A pilot study of human brain tissue post-magnetic resonance imaging: information from the National Deep Brain Stimulation Brain Tissue Network (DBS-BTN).
NeuroImage
2011

Unexpectedly Long-Term Control of Recurrent Gliomatosis Cerebri With Capecitabine: a Possible Molecular Explanation
Neuro-Oncology
2010

Meningiomas Resected During Pregnancy: a Clinicopathologic Study of Eight Patients
Neuro-Oncology
2010

Glioma diagnosis: immunohistochemistry and beyond.
Advances in anatomic pathology
2010

Fragile X dementia Parkinsonism Syndrome (FXDPS).
Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology
2010

Atpyical Presentation and Morbidity With Rituximab in Diffuse Large B-Cell Lymphoma Infiltrating the Spine
Neuro-Oncology
2010

Radiographic and pathologic findings in an atypical brainstem variant of reversible posterior leukoencephalopathy syndrome.
The neurologist
2009

Postmortem interval alters the water relaxation and diffusion properties of rat nervous tissue--implications for MRI studies of human autopsy samples.
NeuroImage
2009

Hematopoietic- and neurologic-expressed sequence 1 expression in the murine GL261 and high-grade human gliomas.
Pathology oncology research : POR
2009

A Posterior Fossa Embryonal Tumor in a 4-Year-Old Male With Features of Atrt But Without Ini1 Mutation
Journal of Neuropathology and Experimental Neurology
2009

The publishing game: reflections of an editorial team.
Laboratory investigation; a journal of technical methods and pathology
2008

Surgical neuropathology update: a review of changes introduced by the WHO classification of tumours of the central nervous system, 4th edition.
Archives of pathology & laboratory medicine
2008

Structure-Based Jaz Ligand-Ji and Its Analogues Show Strong Cytotoxic Effects On Glioma Cells in Vitro - a New Class of Glioma Therapy Drugs?
Journal of Neuropathology and Experimental Neurology
2008

Protocol for the examination of specimens from patients with tumors of the brain/spinal cord.
Archives of pathology & laboratory medicine
2008

Neurotropic melanoma of the trigeminal nerve: a case of atypical facial pain.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
2008

Invasion suppressor cystatin E/M (CST6): high-level cell type-specific expression in normal brain and epigenetic silencing in gliomas.
Laboratory investigation; a journal of technical methods and pathology
2008

Can standard magnetic resonance imaging reliably distinguish recurrent tumor from radiation necrosis after radiosurgery for brain metastases? A radiographic-pathological study.
Neurosurgery
2008

Radiotherapy after subtotally resected or recurrent ganglioglioma.
International journal of radiation oncology, biology, physics
2007

Plexiform-like neurofibromas develop in the mouse by intraneural xenograft of an NF1 tumor-derived Schwann cell line.
Journal of neuroscience research
2007

In vitro studies of steroid hormones in neurofibromatosis 1 tumors and Schwann cells.
Molecular carcinogenesis
2007

Evolutionarily conserved mammalian adenine nucleotide translocase 4 is essential for spermatogenesis.
The Journal of biological chemistry
2007

Diffusion tensor microscopy indicates the cytoarchitectural basis for diffusion anisotropy in the human hippocampus.
AJNR. American journal of neuroradiology
2007

An orthotopic xenograft model of intraneural NF1 MPNST suggests a potential association between steroid hormones and tumor cell proliferation.
Laboratory investigation; a journal of technical methods and pathology
2007

Pontine atypical neurocytoma: case report.
Neurosurgery
2006

Brainstem stereotactic biopsy sampling in children.
Journal of neurosurgery
2006

Pushing the limits of radiotherapy for atypical and malignant meningioma.
American journal of clinical oncology
2005

Paraneoplastic chorea with leukoencephalopathy presenting with obsessive-compulsive and behavioral disorder.
Movement disorders : official journal of the Movement Disorder Society
2005

Neonatal hypothalamic hamartoma: a differentiating nonlethal hamartoblastoma.
Journal of neurosurgery
2005

Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway.
Journal of neuropathology and experimental neurology
2005

Isolated anisocoria from an endodermal cyst of the third cranial nerve mimicking an Adie's tonic pupil.
Journal of pediatric ophthalmology and strabismus
2005

INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma.
Journal of neuropathology and experimental neurology
2005

Clinicopathologic and genetic profile of intracranial marginal zone lymphoma: a primary low-grade CNS lymphoma that mimics meningioma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2005

Secondary leptomeningeal sarcomatosis.
Archives of pathology & laboratory medicine
2004

Primary adenocarcinoma of the vagina with mucinous-enteric differentiation: a report of two cases with associated vaginal adenosis without history of diethylstilbestrol exposure.
Journal of lower genital tract disease
2004

Pituicytoma: report of two cases and clues regarding histogenesis.
Neurosurgery
2004

Images of interest. Gastrointestinal: symptomatic pelvic mass.
Journal of gastroenterology and hepatology
2004

Bone marrow transdifferentiation in brain after transplantation: a retrospective study.
Lancet (London, England)
2004

Giant cell glioblastoma and pleomorphic xanthoastrocytoma show different immunohistochemical profiles for neuronal antigens and p53 but share reactivity for class III beta-tubulin.
Archives of pathology & laboratory medicine
2003

Rhombencephalosynapsis with massive hydrocephalus: case report and pathogenetic considerations.
Acta neuropathologica
2002

Intraoperative consultation for nervous system lesions.
Seminars in diagnostic pathology
2002

Ex vivo high-resolution magnetic resonance imaging of the brain in Joubert's syndrome.
Journal of child neurology
2002

Corticosteroid treatment of mitochondrial encephalomyopathies.
The neurologist
2002

Cortical dysgenesis and epilepsy.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
2002

Tumorigenic properties of neurofibromin-deficient neurofibroma Schwann cells.
The American journal of pathology
2001

Aggressive uterine sarcoma with rhabdoid features: diagnosis by peritoneal fluid cytology and absence of INI1 gene mutation.
Human pathology
2001

CSF cytology of atypical teratoid/rhabdoid tumor of the brain in a two-year-old girl: a case report.
Diagnostic cytopathology
2000

Bcl-2 immunoreactive cells with immature neuronal phenotype exist in the nonepileptic adult human brain.
Journal of neuropathology and experimental neurology
2000

Neuropathology of Joubert syndrome.
Journal of child neurology
1999

Molar tooth sign in Joubert syndrome: clinical, radiologic, and pathologic significance.
Journal of child neurology
1999

Immunohistochemical localization of erythropoietin and its receptor in the developing human brain.
Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society
1999

Cerebellar and brainstem development: an overview in relation to Joubert syndrome.
Journal of child neurology
1999

Tissue distribution of erythropoietin and erythropoietin receptor in the developing human fetus.
Early human development
1998

Microsporidia of the genus Trachipleistophora--causative agents of human microsporidiosis: description of Trachipleistophora anthropophthera n. sp. (Protozoa: Microsporidia).
The Journal of eukaryotic microbiology
1998

Developmental patterns of BCL-2 and BCL-X polypeptide expression in the human spinal cord.
Experimental neurology
1998

Characterization of a primary central nervous system atypical teratoid/rhabdoid tumor and derivative cell line: immunophenotype and neoplastic properties.
Journal of neuropathology and experimental neurology
1998

Neuropathology of pediatric brain tumors.
Seminars in pediatric neurology
1997

Distinct neurodevelopmental patterns of bcl-2 and bcl-x expression are altered in glioneuronal hamartias of the human temporal lobe.
Journal of neuropathology and experimental neurology
1997

Disseminated microsporidiosis in AIDS: are any organs spared?
AIDS (London, England)
1997

Composite pleomorphic xanthoastrocytoma and ganglioglioma: report of four cases and review of the literature.
The American journal of surgical pathology
1997

"Joubert syndrome" revisited: key ocular motor signs with magnetic resonance imaging correlation.
Journal of child neurology
1997

Rapidly progressive dementia: a clinicopathologic correlation.
Journal of geriatric psychiatry and neurology
1996

Glial differentiation predicts poor clinical outcome in primitive neuroectodermal brain tumors.
Annals of neurology
1996

Divergent differentiation in pleomorphic xanthoastrocytoma. Evidence for a neuronal element and possible relationship to ganglion cell tumors.
The American journal of surgical pathology
1996

Disseminated microsporidiosis especially infecting the brain, heart, and kidneys. Report of a newly recognized pansporoblastic species in two symptomatic AIDS patients.
American journal of clinical pathology
1996

Central nervous system medulloepithelioma: a series of eight cases including two arising in the pons.
Journal of neurosurgery
1996

Primary intracranial atypical teratoid/rhabdoid tumor in a child with Canavan disease.
Pediatric neurosurgery
1995

Neurofibromatosis type 1: pathologic substrate of high-signal-intensity foci in the brain.
Radiology
1995

Neurofibromatosis type 1.
Medical and pediatric oncology
1995

Congenital CNS primitive neuroectodermal tumor: case report and review of the literature.
Pediatric pathology & laboratory medicine : journal of the Society for Pediatric Pathology, affiliated with the International Paediatric Pathology Association
1995

Brainstem neoplasms.
Medical and pediatric oncology
1995

Subependymal giant cell astrocytomas in children.
Pediatric neurosurgery
1994

Studies of childhood brain tumors using immunohistochemistry and microwave technology: methodological considerations.
Journal of neuroscience methods
1994

In vivo and in vitro models of medulloblastomas and other primitive neuroectodermal brain tumors of childhood.
Molecular and chemical neuropathology
1994

Cerebellar dysplasias in humans: development and possible relationship to glial and primitive neuroectodermal tumors of the cerebellar vermis.
Journal of neuropathology and experimental neurology
1994

Acute subdural hematoma: is the blood itself toxic?
Journal of neurotrauma
1994

The Golgi apparatus of motor neurons in amyotrophic lateral sclerosis.
Annals of neurology
1993

Isolated extranodal intracranial sinus histiocytosis in a 5-year-old boy. Case report.
Journal of neurosurgery
1993

Ganglioglioma.
Medical and pediatric oncology
1993

Expression of neuronal and glial polypeptides during histogenesis of the human cerebellar cortex including observations on the dentate nucleus.
The Journal of comparative neurology
1993

Expression of the neu proto-oncogene by Schwann cells during peripheral nerve development and Wallerian degeneration.
Journal of neuroscience research
1992

Desmoplastic primitive neuroectodermal tumor with divergent differentiation. Broadening the spectrum of desmoplastic infantile neuroepithelial tumors.
The American journal of surgical pathology
1992

Isolated one-and-a-half syndrome with pontine cavernous angioma: successful surgical removal.
Journal of clinical neuro-ophthalmology
1990

Expression of neurofilament proteins in the hypertrophic granule cells of Lhermitte-Duclos disease: an explanation for the mass effect and the myelination of parallel fibers in the disease state.
Journal of neuropathology and experimental neurology
1988

Cytologic detection of amyloid in duodenal and ureteral brushings.
Diagnostic cytopathology
1988

The antagonism of bombesin in the CNS by substance P analogues.
Life sciences
1984

Stimulation of DNA synthesis in Balb/c 3T3 cells by peripheral nerve degenerating in vitro.
Experimental neurology
1982

Mitogenic effect of myelinated vs unmyelinated garfish nerve extracts.
Brain research
1982