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Jennifer L Miller, MD : Research

Pediatric Endocrinologist (Child Hormone Specialist)

Photo of Jennifer L Miller

Research at a glance

Top areas of exploration

  • Prader-Willi Syndrome , 48 publications
  • Hyperphagia , 8 publications
  • Chromosomes, Human, Pair 15 , 8 publications
  • Obesity , 7 publications

Research activity

69 publications

3,235 citations

Why is this important?

Focus

My research focuses on investigation of the etiology and possible treatment for obesity and metabolic abnormalities in individuals with Prader-Willi syndrome and early-onset obesity. I have been working towards achieving an appropriate treatment for hyperphagia for the past 12 years. I currently follow over 500 patients with Prader-Willi syndrome from around the world, and over 100 patients with early-onset obesity due to other genetic causes. I am working on clinical treatment trials to treat hyperphagia in individuals with Prader-Willi syndrome and early-onset obesity..

Active clinical trials

TRYP-001

To better understand the potential benefits of psychedelics in overeating disorders, Tryp Therapeutics will conduct a safety and feasibility clinical trial using TRP 8802 among individuals with Binge Eating Disorder. This is a single-center phase 2a…

Investigator
Jennifer L Miller
Status
Accepting Candidates
Ages
18 Years - 64 Years
Sexes
All
HBS-101-CL-002

The primary objective of this study is to evaluate the safety and efficacy of pitolisant compared with placebo in treating excessive daytime sleepiness (EDS) in patients with Prader Willi syndrome (PWS) ages 6 to 65 years.

Investigator
Jennifer L Miller
Status
Accepting Candidates
Ages
6 Years - 65 Years
Sexes
All

My publications

69 publications

2025

Hyperphagia in rare melanocortin-4 receptor pathway diseases: therapeutic options and assessing treatment response

Reviews in Endocrine and Metabolic Disorders

Publisher's site

2024

Behavioral changes in patients with Prader-Willi syndrome receiving diazoxide choline extended-release tablets compared to the PATH for PWS natural history study.

Journal of neurodevelopmental disorders

PubMed Publisher's site

2024

Diazoxide choline extended-release tablet in people with Prader-Willi syndrome: results from long-term open-label study.

Obesity (Silver Spring, Md.)

PubMed Publisher's site

2024

Neuromodulation for the treatment of Prader-Willi syndrome - A systematic review.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics

PubMed Publisher's site

2023

Diazoxide Choline Extended-Release Tablet in People With Prader-Willi Syndrome: A Double-Blind, Placebo-Controlled Trial

The Journal of Clinical Endocrinology & Metabolism

PubMed Publisher's site