Eileen Handberg, Ph.D.

Eileen M Handberg, Ph.D., ARNP - Research & Publications

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Publications

Maladaptive Left Ventricular Remodeling in Women: An Analysis From the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study
International journal of cardiology
2018

Late sodium channel blockade improves angina and myocardial perfusion in patients with severe coronary microvascular dysfunction: Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction ancillary study.
International journal of cardiology
2018

Intensive Blood Pressure Lowering Reduces Adverse Cardiovascular Outcomes Among Patients With High-Normal Glucose: An Analysis From the Systolic Blood Pressure Intervention Trial Database
Journal of Clinical Hypertension
2018

Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure.
International journal of cardiology
2018

Ten-Year Mortality in the Wise Study (Women's Ischemia Syndrome Evaluation)
Circulation-Cardiovascular Quality and Outcomes
2017

Sex Impacts the Flow-Mediated Dilation Response to Acute Aerobic Exercise in Older Adults
Experimental Gerontology
2017

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: the Cctrn Pace Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells)
Circulation
2017

Effect of Low-Furanocoumarin Hybrid Grapefruit Juice Consumption on Midazolam Pharmacokinetics

2017

Daily Activity Measured With Wearable Technology As a Novel Measurement of Treatment Effect in Patients With Coronary Microvascular Dysfunction: Substudy of a Randomized Controlled Crossover Trial

2017

All-Extremity Exercise Training Improves Arterial Stiffness in Older Adults
Medicine and Science in Sports and Exercise
2017

Acetylcholine Versus Cold Pressor Testing for Evaluation of Coronary Endothelial Function
PLOS One
2017

Psychosocial Predictors of Long-Term Mortality Among Women With Suspected Myocardial Ischemia: the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation
Journal of Behavioral Medicine
2016

Novel All-Extremity High-Intensity Interval Training Improves Aerobic Fitness, Cardiac Function and Insulin Resistance in Healthy Older Adults
Experimental Gerontology
2016

Mortality Risk Associated With Resistant Hypertension Among Women: Analysis From Three Prospective Cohorts Encompassing the Spectrum of Women's Heart Disease
Journal of Womens Health
2016

Long-Term Mortality in Hypertensive Patients With Coronary Artery Disease: Results From the US Cohort of the International Verapamil (Sr)/Trandolapril Study
Hypertension
2016

Circulating Progenitor Cells and Coronary Microvascular Dysfunction: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction Study (Wise-Cvd)
Atherosclerosis
2016

A Randomized, Placebo-Controlled Trial of Late Na Current Inhibition (Ranolazine) in Coronary Microvascular Dysfunction (Cmd): Impact on Angina and Myocardial Perfusion Reserve

2016

Renal Function and Coronary Microvascular Dysfunction in Women With Symptoms/Signs of Ischemia
PLOS One
2015

Mild Renal Dysfunction and Long-Term Adverse Outcomes in Women With Chest Pain: Results From the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
American Heart Journal
2015

Impact of Aspirin According To Type of Stable Coronary Artery Disease: Insights From a Large International Cohort
American Journal of Medicine
2015

Effects of Verapamil Sr and Atenolol On 24-Hour Blood Pressure and Heart Rate in Hypertension Patients With Coronary Artery Disease: An International Verapamil Sr-Trandolapril Ambulatory Monitoring Substudy
PLOS One
2015

Cardiac Magnetic Resonance Myocardial Perfusion Reserve Index Is Reduced in Women With Coronary Microvascular Dysfunction a National Heart, Lung, and Blood Institute-Sponsored Study From the Women's Ischemia Syndrome Evaluation
Circulation-Cardiovascular Imaging
2015

Timi Frame Count and Adverse Events in Women With No Obstructive Coronary Disease: a Pilot Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
PLOS One
2014

Relationships Between Depression, Dietary Habits, and Cardiovascular Mortality and Events Among Women With Suspected Myocardial Ischemia
Psychosomatic Medicine
2014

Predictors and Outcomes of Resistant Hypertension Among Patients With Coronary Artery Disease and Hypertension
Journal of Hypertension
2014

Comparison of Low and High Dose Intracoronary Adenosine and Acetylcholine in Women Undergoing Coronary Reactivity Testing: Results From the Nhlbi-Sponsoredwomen's Ischemia Syndrome Evaluation (Wise)

2014

Aldosterone Inhibition and Coronary Endothelial Function in Women Without Obstructive Coronary Artery Disease: An Ancillary Study of the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation
American Heart Journal
2014

Simple Integer Risk Score To Determine Prognosis of Patients With Hypertension and Chronic Stable Coronary Artery Disease

2013

Number and Function of Bone-Marrow Derived Angiogenic Cells and Coronary Flow Reserve in Women Without Obstructive Coronary Artery Disease: a Substudy of the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
PLOS One
2013

Mortality Implications of Angina and Blood Pressure in Hypertensive Patients With Coronary Artery Disease: New Data From Extended Follow-Up of the International Verapamil/Trandolapril Study (Invest)
Clinical Cardiology
2013

Mild Renal Insufficiency Predicts Mortality and Adverse Events in Women With Cardiac Ischemia, Independent of the Underlying Obstructive Coronary Artery Disease
Circulation
2013

Mild Renal Insufficiency Is An Independent Predictor of Coronary Microvascular Dysfunction Among Women With Symptoms/Signs of Ischemia: a Report From the Women's Ischemia Syndrome Evaluation (Wise)
Circulation
2013

Increased Circulating Progenitor Cells in Women With Microvascular Coronary Dysfunction: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction Study (Wise-Cvd)
Circulation
2013

Electromechanical Assessment of Myocardial Function Is Associated With Improvement in Ejection Fraction in Patients Treated With Autologous Stem Cell Therapy for Ischemic Cardiomyopathy
Circulation
2013

Electromechanical Assessment of Myocardial Function (Noga) Is Associated With Exercise Improvement in Patients Treated With Autologous Stem Cell Therapy for Refractory Angina

2013

Clinical implications of the Women’s Ischemia Syndrome Evaluation: inter-relationships between symptoms, psychosocial factors and cardiovascular outcomes.
Women's Health (Lond Engl)
2013

Anginal Symptoms, Coronary Artery Disease, and Adverse Outcomes in Black and White Women: the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise) Study
Journal of Womens Health
2013

Treatment-Resistant Blood Pressure Among Patients With Coronary Artery Disease - Cause for Concern: New Data From the Extended Follow-Up of the International Verapamail Sr-Trandolapril Study (Invest)

2012

Simple Prediction of Long-Term Mortality Among Hypertensive Patients With Coronary Artery Disease: New Data From An Extended Follow-Up of the International Verapamil-Sr/Trandolapril Study (Invest)

2012

Safety of Coronary Reactivity Testing in Women With No Obstructive Coronary Artery Disease
Jacc-Cardiovascular Interventions
2012

Relationships Between Components of Metabolic Syndrome and Coronary Intravascular Ultrasound (Ivus) Atherosclerosis Measures in Women Without Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation (Wise) Study

2012

Relationships Between Cardiovascular Disease Risk Factors and Depressive Symptoms as Predictors of Cardiovascular Disease Events in Women
Journal of Womens Health
2012

Mortality Associated With Angina and Blood Pressure Control Among Hypertensive Patients With Coronary Artery Disease: New Data From Extended Follow-Up of the International Verapamil/Trandolapril Study

2012

Modest Increase in Peak Vo2 Is Related To Better Clinical Outcomes in Chronic Heart Failure Patients Results From Heart Failure and a Controlled Trial To Investigate Outcomes of Exercise Training
Circulation-Heart Failure
2012

How Do Guidelines Impact Measures of Performance? Can They Keep Up?
Archives of Internal Medicine
2012

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery On Left Ventricular Function After Acute Myocardial Infarction the Time Randomized Trial
Jama-Journal of the American Medical Association
2012

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells On Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure the Focus-Cctrn Trial
Jama-Journal of the American Medical Association
2012

Differential Effects of Cold Pressor and Acetylcholine During Endothelial Function Assessment in Women With No Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation (Wise) Study

2012

Combining Psychosocial Data To Improve Prediction of Cardiovascular Disease Risk Factors and Events: the National Heart, Lung, and Blood Institute-Sponsored Women'S Ischemia Syndrome Evaluation Study
Psychosomatic Medicine
2012

An Injectable Acellular Capillary Hydrogel Improves Left Ventricular Function After Myocardial Infarction

2012

A Degradable, Bioactive, Gelatinized Alginate Hydrogel To Improve Stem Cell/Growth Factor Delivery and Facilitate Healing After Myocardial Infarction
Medical Hypotheses
2012

Relationship Between Coronary Micro- and Macrovascular Measures in Women With Chest Pain Without Significant Coronary Artery Disease: An Ancillary Substudy From the Nhbli-Sponsored Women's Ischemia Syndrome Evaluation (Wise)

2011

Oversight and Management of a Cell Therapy Clinical Trial Network: Experience and Lessons Learned
Contemporary Clinical Trials
2011

In Women With Symptoms of Cardiac Ischemia, Nonobstructive Coronary Arteries, and Microvascular Dysfunction, Angiotensin-Converting Enzyme Inhibition Is Associated With Improved Microvascular Function: a Double-Blind Randomized Study From the National Heart, Lung and Blood Institute Women'S Ischemia Syndrome Evaluation (Wise)
American Heart Journal
2011

Harmful Effects of Nsaids Among Patients With Hypertension and Coronary Artery Disease
American Journal of Medicine
2011

Effect of Phosphodiesterase Type 5 Inhibition On Microvascular Coronary Dysfunction in Women: a Women's Ischemia Syndrome Evaluation (Wise) Ancillary Study
Clinical Cardiology
2011

Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 To 3 Weeks Following Acute Myocardial Infarction On Left Ventricular Function the Latetime Randomized Trial
Jama-Journal of the American Medical Association
2011

Does Angiotensin Plus Aldosterone Inhibition Improve Coronary Endothelial Function? An Ancillary Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)

2011

Could Retinal Imaging Provide a Simple, Inexpensive, Noninvasive Index for Coronary Microvascular Function in Women With Chest Pain and Nonobstructive Coronary Artery Disease? An Ancillary Pilot Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise-Aric)

2011

Antiplatelet Therapy in Acute Coronary Syndromes Implications for Nursing Practice
Journal of Cardiovascular Nursing
2011

Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease.
Jama-Journal of the American Medical Association
2010

Tight Blood Pressure Control and Cardiovascular Outcomes Among Hypertensive Patients With Diabetes and Coronary Artery Disease
Jama-Journal of the American Medical Association
2010

Outcomes Among hypertensive patients with concomitant peripheral and coronary artery disease: findings from the INternational VErapamil-SR/Trandolapril STudy.
Hypertension
2010

Outcomes Among Hypertensive Patients With Concomitant Peripheral and Coronary Artery Disease Findings From the International Verapamil-Sr/Trandolapril Study
Hypertension
2010

Coronary revascularization strategy and outcomes according to blood pressure (from the International Verapamil SR-Trandolapril Study [INVEST]).
American Journal of Cardiology
2010

Coronary microvascular reactivity to adenosine predicts adverse outcome in women evaluated for suspected ischemia results from the National Heart, Lung and Blood Institute WISE (Women's Ischemia Syndrome Evaluation) study.

2010

Coronary Microvascular Reactivity To Adenosine Predicts Adverse Outcome in Women Evaluated for Suspected Ischemia Results From the National Heart, Lung and Blood Institute Wise (Women's Ischemia Syndrome Evaluation) Study

2010

Blood pressure and outcomes in very old hypertensive coronary artery disease patients: an INVEST substudy.
The American journal of medicine. Supplement
2010

An Intravascular Ultrasound Analysis in Women Experiencing Chest Pain in the Absence of Obstructive Coronary Artery Disease: a Substudy From the National Heart, Lung and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of Interventional Cardiology
2010

A Randomized Controlled Trial of Low-Dose Hormone Therapy On Myocardial Ischemia in Postmenopausal Women With No Obstructive Coronary Artery Disease: Results From the National Institutes of Health/National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
American Heart Journal
2010

Systolic Blood Pressure and Subjective Well-Being in Patients With Coronary Artery Disease
Clinical Cardiology
2009

New York Heart Association Functional Class Predicts Exercise Parameters in the Current Era
American Heart Journal
2009

Multimarker Approach Predicts Adverse Cardiovascular Events in Women Evaluated for Suspected Ischemia: Results From the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation
Clinical Cardiology
2009

Long-Term Mortality Associated With New Onset Diabetes in Hypertensive Cad Patients Following Exposure To Antihypertensive Medications: Findings From the International Verapamail Sr-Trandolapril Study (Invest)

2009

Incident Or Continued Angina During Hypertension Treatment Is Associated With Increased Risk of Death, Mi, Or Stroke Among Patients With Known Cad: a Substudy of the International Verapamil/Trandolapril Study (Invest)
Circulation
2009

INVEST revisited: review of findings from the International Verapamil SR-Trandolapril Study.
Expert Review of Cardiovascular Therapy
2009

Depression and Cardiovascular Health Care Costs Among Women With Suspected Myocardial Ischemia Prospective Results From the Wise (Women's Ischemia Syndrome Evaluation) Study

2009

Characteristics and outcomes of revascularized patients with hypertension: an international verapamil SR-trandolapril substudy.
Hypertension
2009

Characteristics and Outcomes of Revascularized Patients With Hypertension An International Verapamil Sr-Trandolapril Substudy
Hypertension
2009

Adverse Cardiovascular Outcomes in Women With Nonobstructive Coronary Artery Disease a Report From the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project
Archives of Internal Medicine
2009

Pulse Pressure and Adverse Outcomes in Women: a Report From the Women'S Ischemia Syndrome Evaluation (Wise)
American Journal of Hypertension
2008

Impact of Resting Heart Rate On Outcomes in Hypertensive Patients With Coronary Artery Disease: Findings From the International Verapamil-Sr/Trandolapril Study (Invest)

2008

The ICD shock and stress management program: a randomized trial of psychosocial treatment to optimize quality of life in ICD patients.
Pacific Economic Review
2007

Influence of Hispanic ethnicity on blood pressure control and cardiovascular outcomes in women with CAD and hypertension: findings from INVEST.
Journal of Womens Health
2007

Validating a self-report measure of global subjective well-being to predict adverse clinical outcomes.
Quality of Life Research
2006

Quality of death: implantable cardioverter defibrillators and proactive care.
Pacific Economic Review
2006

Predictors of adverse outcome among patients with hypertension and coronary artery disease.

2006

Impaired coronary vascular reactivity and functional capacity in women: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE) Study.

2006

End-of-life issues in elderly patients with acute coronary syndrome: the role of the cardiovascular nurse.
Progress in cardiovascular nursing
2006

Management of heart failure after cardiac resynchronization therapy: integrating advanced heart failure treatment with optimal device function.

2005

Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women.
Jama-Journal of the American Medical Association
2004

Characteristics of contemporary patients with hypertension and coronary artery disease.
Clinical Cardiology
2004

Young at heart: understanding the unique psychosocial adjustment of young implantable cardioverter defibrillator recipients.
Pacific Economic Review
2001

Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension.

1998

Rationale and Design of the International Verapamil SR/Trandolapril Study (INVEST): An Internet-Based Randomized Trial in Coronary Artery Disease Patients with Hypertension

1998

Effects of intermittent transdermal nitroglycerin on occurrence of ischemia after patch removal: results of the second transdermal intermittent dosing evaluation study (TIDES-II).

1997

Research Interests