Herbert Ward, M.D.

Herbert E Ward, Jr, M.D.

(352) 265-4357

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Publications

Depressive Symptoms Are Frequent in Atypical Parkinsonian Disorders
Movement Disorders Clinical Practice
2017

Six-Nine Year Follow-Up of Deep Brain Stimulation for Obsessive-Compulsive Disorder
PLoS One
2016

Scheduled, Intermittent Stimulation of the Thalamus Reduces Tics in Tourette Syndrome
Parkinsonism & Related Disorders
2016

Overview of the Current Use of Deep Brain Stimulation in Psychiatric Disorders
Psychiatric Annals
2016

Interdisciplinary Parkinson's Disease Deep Brain Stimulation Screening and the Relationship to Unintended Hospitalizations and Quality of Life
PLoS One
2016

Impact of An Interdisciplinary Deep Brain Stimulation Screening Model on Post-Surgical Complications in Essential Tremor Patients
PLoS One
2015

Impulsive and Compulsive Behaviors in Parkinson Study Group (Psg) Centers Performing Deep Brain Stimulation Surgery
Journal of Parkinsons Disease
2014

An Eight-Year Clinic Experience With Clozapine Use in a Parkinson's Disease Clinic Setting
PLoS One
2014

Acute and Chronic Mood and Apathy Outcomes From a Randomized Study of Unilateral Stn and Gpi Dbs
PLoS One
2014

Differential and Better Response To Deep Brain Stimulation of Chorea Compared To Dystonia in Huntington's Disease
Stereotactic and Functional Neurosurgery
2013

Clozapine as a Potential Treatment for Refractory Impulsive, Compulsive, and Punding Behaviors in Parkinson's Disease
Neurocase
2013

A Trial of Scheduled Deep Brain Stimulation for Tourette Syndrome Moving Away From Continuous Deep Brain Stimulation Paradigms
JAMA neurology
2013

Rebound Symptoms Following Battery Depletion in the Nih Ocd Dbs Cohort: Clinical and Reimbursement Issues

2012

Effects of Stn and Gpi Deep Brain Stimulation On Impulse Control Disorders and Dopamine Dysregulation Syndrome
PLoS One
2012

Are Selective Serotonin Reuptake Inhibitors Associated With Greater Apathy in Parkinson's Disease?
Journal of Neuropsychiatry and Clinical Neurosciences
2012

Smile and Laughter Induction and Intraoperative Predictors of Response To Deep Brain Stimulation for Obsessive-Compulsive Disorder
NeuroImage
2011

Do Stable Patients With a Premorbid Depression History Have a Worse Outcome After Deep Brain Stimulation for Parkinson Disease?
Neurosurgery
2011

Do Patient's Get Angrier Following Stn, Gpi, and Thalamic Deep Brain Stimulation
NeuroImage
2011

Addiction-like manifestations and Parkinson’s disease: a large single center 9 -year experience
The Journal of Neuroscience
2011

Update On Deep Brain Stimulation for Neuropsychiatric Disorders
Neurobiology of Disease
2010

Right and left dorsolateral pre-frontal rTMS treatment of refractory depression: A randomized, sham-controlled trial
Psychiatry Research
2010

Prevalence of Twiddler's Syndrome as a Cause of Deep Brain Stimulation Hardware Failure
Stereotactic and Functional Neurosurgery
2010

Lack of Benefit of Accumbens/Capsular Deep Brain Stimulation in a Patient With Both Tics and Obsessive-Compulsive Disorder
Neurocase
2010

Deep Brain Stimulation for Intractable Obsessive Compulsive Disorder: Pilot Study Using a Blinded, Staggered-Onset Design
Biological Psychiatry
2010

A Case of Mania Following Deep Brain Stimulation for Obsessive Compulsive Disorder
Stereotactic and Functional Neurosurgery
2010

Combination of antidepressant medications from treatment initiation for major depressive disorder: a double-blind randomized study
The American Journal of Psychiatry
2010

Cognition and Mood in Parkinson's Disease in Subthalamic Nucleus Versus Globus Pallidus Interna Deep Brain Stimulation: the Compare Trial
Annals of Neurology
2009

A Small Pilot Study of Smile Induction in the Nih Ocd Dbs Cohort: a Potential Predictor of Therapy Response?
Annals of Neurology
2009

Neurobiological and Clinical Effects of Combining Two Antidepressant Medications From the Start
International Journal of Neuropsychopharmacology
2008

A pilot study of vagus nerve stimulation (VNS) for treatment-resistant anxiety disorders
Brain Stimulation
2008

A Pilot Study of Vagus Nerve Stimulation (Vns) for Treatment-Resistant Anxiety Disorders

2008

Clinical predictors of early fluoxetine treatment response in obsessive-compulsive disorder
Depression and Anxiety
2006

A double-blind, placebo-controlled trial of olanzapine addition in fluoxetine-refractory obsessive-compulsive disorder
Biological Psychiatry
2004

Depression and cardiovascular disease
Current Opinion in Psychiatry
2003

Toward optimal treatments for major depression.
CNS Spectrums
2002

Understanding generalized anxiety disorder
Academic Emergency Medicine
2001

Effects of prenatal stress on defensive withdrawal behavior and corticotropin releasing factor systems in rat brain
Physiology & behavior
2000

Depression in the medical setting: Biopsychological interactions and treatment considerations
Journal of Clinical Psychiatry
1999

The Newer Antidepressants
Jacksonville Medicine
1998

Religious knowledge and its use in psychiatry
Journal of Religion & Health
1998

Psychiatric morbidity in endocrine disorders
Psychiatric Clinics of North America
1998

Corticotropin-releasing factor and defensive withdrawal: inhibition of monoamine oxidase prevents habituation to chronic stress
Pharmacology Biochemistry and Behavior
1998

Fluvoxamine in the treatment of obsessive compulsive disorder and related conditions
Journal of Clinical Psychiatry
1997

Depression in the medically ill: Management considerations.
Depression and Anxiety
1997

Prenatal stress increases corticotropin-releasing factor (CRF) content and release in rat amygdala minces
Brain Research
1995

An animal model for anxiety: Effects of corticotropin releasing factor and chronic stress
West Virginia Journal Psychology Research and Practice
1993

Synthesis and preliminary pharmacology of an internal standard for assay of neostigmine
Journal of Pharmaceutical Sciences
1981

Antagonism of methylphenidateinduced behavior by neostigmine or hemicholinium3
Neuropharmacology
1981

A Pharmacology experiment to demonstrate the cardiovascular effects of drugs in the rat in situ
American Journal of Pharmaceutical Education
1980

Research Interests

Research and Scholarly Interests:

Dr. Ward has been a pioneer in the development of brain stimulation treatments for psychiatric diseases. His research in this area with Drs Foote, Okun, and Goodman have been widely referenced and led to the University of Florida being one of the pivotal sites in the evaluation of DBS in OCD. He is also a key investigator in a RO-1 to evaluate DBS in major depression. His overall interests come out of a background in pharmacology and specialty training in medicine, depression, and anxiety disorders. He is interested in the neurobiology of anxiety and the development of new treatment strategies, including combination therapies for optimal synaptic benefit and reduction of adverse effects. Additionally, he is interested in improving recognition of anxiety disorders in primary care and testing a parallel model for delivery of medical and psychiatric services. His recent peer reviewed, high impact publications are listed on this page.

Educational Interests and Accomplishments:

Dr. Ward is very interested in the application of formal clinical decision making to the field of psychiatry. He teaches Psychiatrists-in-training, medical students, internal medicine and other Residents, and Fellows in his clinic. It is both highly rated and a very effective clinical setting to train new academic Faculty. Since the psychiatric interview is the "gold standard" for detecting disease, psychiatry has lagged behind other specialties in using Bayesian analysis to enrich our clinical impression and guide treatment. He also enjoys teaching residents how to integrate pharmacotherapy and psychotherapy, i.e., how to establish a psycho-social gradient that favors a desired drug response. He has contributed to the medical school curriculum development by serving on the Interdisciplinary Generalist Clerkship Curriculum Committee and the Task Force on Vertical Integration of Neurobehavioral Sciences. Dr. Ward has received the departmental Teacher of the Year award and served on Departmental Graduate Education Committee and Resident Recruitment Committee.