Jacqueline Hobbs, M.D.

Jacqueline A Hobbs, M.D., Ph.D.

(352) 265-4357

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Publications

Othello Syndrome: Delusional Disorder - Jealous Type ≠ Violence.
CNS spectrums
2021

Improved cell-specificity of adeno-associated viral vectors for medullary thyroid carcinoma using calcitonin gene regulatory elements.
PloS one
2020

Associations Between National Board Exam Performance and Residency Program Emphasis on Patient Safety and Interprofessional Teamwork.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry
2019

The virus connection: understanding how viruses affect psychiatric pathologies

2016

Primate erythroparvovirus 1 (Parvovirus B19): an etiologic agent of ataxia and cerebellar disease?
Journal of Neuroinfectious Diseases
2016

How do viruses really cause neuropathology?: Is there more to the story?
Journal of Neuroinfectious Diseases
2016

Parvovirus and thyroid cancer.
Seminars in oncology
2015

Persistent parvovirus B19 infection in non-erythroid tissues: possible role in the inflammatory and disease process.
Virus research
2014

Parvovirus b19 persistence in abnormal thyroid tissue of a mature cystic ovarian teratoma: a case report.
Endocrine pathology
2014

Infection and persistence of erythrovirus B19 in benign and cancerous thyroid tissues.
Journal of medical virology
2014

Trends in performance on the psychiatry resident-in-training examination (PRITE®): 10 years of data from a single institution.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry
2013

Increased IL-6 detection in adult and pediatric lymphoid tissue harboring parvovirus B19.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
2013

Human parvovirus B19 infection leads to downregulation of thyroid, estrogen, and retinoid hormone receptor expression.
Virology
2013

Thyroid dysfunction as a contributor to mood and psychotic disorders

2012

Detection of parvovirus B19 capsid proteins in testicular tissues.
Urology
2012

Parvovirus B19 infection in Hashimoto's thyroiditis, papillary thyroid carcinoma, and anaplastic thyroid carcinoma.
Thyroid : official journal of the American Thyroid Association
2011

Refining the human behavior small group experience.
Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry
2010

Persistent adeno-associated virus 2 and parvovirus B19 sequences in post-mortem human cerebellum.
Cerebellum (London, England)
2009

Tyrosine-phosphorylation of AAV2 vectors and its consequences on viral intracellular trafficking and transgene expression.
Virology
2008

Next generation of adeno-associated virus 2 vectors: point mutations in tyrosines lead to high-efficiency transduction at lower doses.
Proceedings of the National Academy of Sciences of the United States of America
2008

Parvovirus B19-brain interactions: infection, autoimmunity, or both?
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology
2007

Parvovirus B19 infection of brain: possible role of gender in determining mental illness and autoimmune thyroid disorders.
Medical hypotheses
2007

Detection of adeno-associated virus 2 and parvovirus B19 in the human dorsolateral prefrontal cortex.
Journal of neurovirology
2006

Requirement of caspase-3 for efficient apoptosis induction and caspase-7 activation but not viral replication or cell rounding in cells infected with vesicular stomatitis virus.
Human immunology
2003

Developmental aspects of panic and related anxiety disorders

2003

Selective loss of natural killer T cells by apoptosis following infection with lymphocytic choriomeningitis virus
Journal Of Virology
2001

Generation of cellular immunity to lymphocytic choriomeningitis virus is independent of CD1d1 expression
Immunology
2001

Caspase-3-like proteases are activated by infection but are not required for replication of vesicular stomatitis virus
Virus Research
2001

Over-expression of multidrug resistance P-glycoprotein inhibits NK granule-mediated lytic ability without affecting the Fas lytic pathway
Human Immunology
1999

Effect of Fas+ and Fas- target cells on the ability of NK cells to repeatedly fragment DNA and trigger lysis via the Fas lytic pathway
Apoptosis
1998

Fas involvement in cytotoxicity mediated by human NK cells
Cellular Immunology
1995

Research Interests

Clinical Interests:

Dr. Hobbs' clinical interests include schizophrenia and other psychoses, bipolar disorder, women's mental health and thyroid disorders/cancer.

Research and Scholarly Interests:

Dr. Hobbs' research interests include neurovirology, animal models of virus infection in the developing brain, viral/infectious etiologies of schizophrenia and bipolar disorder as well as other mental illnesses, and viral etiologies of thyroid disease/cancer.

Educational Interests and Accomplishments:

Dr. Hobbs serves as the Residency Training Director. She also supervises residents in her Women's Mental Health Clinic and the on-call service. She also values the one-on-one teaching of residents/fellows/students in the laboratory. Dr. Hobbs regularly lectures on general psychiatric topics and neurobiology for medical and physician-assistant students.