Marcus Muehlbauer, M.D.

Marcus Muehlbauer, M.D., Ph.D. - Research & Publications

(352) 273-9400

Request an Appointment

Publications

Characterization Of The Human Zinc Finger Protein 267 Promoter: Essential Role Of Nuclear Factor Y.
Biochimica Et Biophysica Acta
2019

Differential Effects Of Deoxycholic Acid And Taurodeoxycholic Acid On Nf-Kappa B Signal Transduction And Il-8 Gene Expression In Colonic Epithelial Cells.
American Journal of Physiology-Gastrointestinal and Liver Physiology
2019

Interleukin-8 Expression Is Regulated By Histone Deacetylases Through The Nuclear Factor-Kappab Pathway In Breast Cancer.
Molecular Pharmacology
2019

Repression Of Cytochrome P450 Activity In Human Hepatocytes In Vitro By A Novel Hepatotrophic Factor, Augmenter Of Liver Regeneration.
The Journal of pharmacology and experimental therapeutics
2019

Reduced Expression Of Fibroblast Growth Factor Receptor 2Iiib In Hepatocellular Carcinoma Induces A More Aggressive Growth.
The American Journal Of Pathology
2019

Role Of Tlr9 In Hepatic Stellate Cells And Experimental Liver Fibrosis.
Biochemical and Biophysical Research Communications
2019

Stochastic Changes Over Time and Not Founder Effects Drive Cage Effects in Microbial Community Assembly in a Mouse Model
The ISME Journal
2019

Detection Of Melanoma Cells In The Blood Of Melanoma Patients By Melanoma-Inhibitory Activity (Mia) Reverse Transcription-Pcr.
Clinical Cancer Research
1999

Modulation Of The Intestinal Microbiota Alters Colitis-Associated Colorectal Cancer Susceptibility.
Plos One
2019

In Situ Expression Patterns Of Melanoma Inhibitory Activity 2 In Healthy And Diseased Livers.
Liver International : Official Journal Of The International Association For The Study Of The Liver
2019

Vsl\#3 Probiotic Modifies Mucosal Microbial Composition But Does Not Reduce Colitis-Associated Colorectal Cancer
Scientific Reports
2019

Tomato Lycopene Extract Prevents Lipopolysaccharide-Induced Nf-Kappab Signaling But Worsens Dextran Sulfate Sodium-Induced Colitis In Nf-Kappabegfp Mice.
Plos One
2019

Microbial Colonization Induces Dynamic Temporal And Spatial Patterns Of Nf-Κb Activation In The Zebrafish Digestive Tract.
Gastroenterology
2019

Different Effects Of A Cd14 Gene Polymorphism On Disease Outcome In Patients With Alcoholic Liver Disease And Chronic Hepatitis C Infection.
World Journal of Gastroenterology
2019

Microbial Host Interactions In Ibd: Implications For Pathogenesis And Therapy.
Current Gastroenterology Reports
2019

The Innate Immune Receptor Nlrx1 Functions As a Tumor Suppressor By Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals
Cell Reports
2019

Oxymatrine Prevents Nf-Κb Nuclear Translocation And Ameliorates Acute Intestinal Inflammation.
Scientific Reports
2019

Tumor Necrosis Factor And Interferon-Gamma Down-Regulate Klotho In Mice With Colitis.
Gastroenterology
2019

Impaired Bcl3 Up-Regulation Leads To Enhanced Lipopolysaccharide-Induced Interleukin (Il)-23P19 Gene Expression In Il-10(-/-) Mice.
The Journal of biological chemistry
2019

A Novel Mcp-1 Gene Polymorphism Is Associated With Hepatic Mcp-1 Expression And Severity Of Hcv-Related Liver Disease.
Gastroenterology
2019

Gnotobiotic Il-10-/-;Nf-Kappa B(Egfp) Mice Reveal The Critical Role Of Tlr/Nf-Kappa B Signaling In Commensal Bacteria-Induced Colitis.
Journal of immunology (Baltimore, Md. : 1950)
2019

Locoregional Effects Of Microbiota In A Preclinical Model Of Colon Carcinogenesis.
Cancer Research
2019

Activated Hepatic Stellate Cells Express Keratinocyte Growth Factor In Chronic Liver Disease.
American Journal of Pathology
2019

Zinc Finger Protein 267 Is Up-Regulated During The Activation Process Of Human Hepatic Stellate Cells And Functions As A Negative Transcriptional Regulator Of Mmp-10.
Biochemical and Biophysical Research Communications
2019

Lps-Mediated Nfkappab Activation Varies Between Activated Human Hepatic Stellate Cells From Different Donors.
Biochemical and Biophysical Research Communications
2019

Inflammasome-Independent Role of Aim2 in Suppressing Colon Tumorigenesis Via Dna-Pk and Akt
Nature Medicine
2019

Activated Hepatic Stellate Cells Promote Tumorigenicity Of Hepatocellular Carcinoma.
Cancer Science
2019

A Cell Permeable Peptide Inhibitor Of Nfat Inhibits Macrophage Cytokine Expression And Ameliorates Experimental Colitis.
Plos One
2019

Glass Microparticulate Ingestion: An Unusual And Difficult-To-Diagnose Cause Of Chronic Abdominal Pain.
Acg Case Reports Journal
2019

Strong Expression Of Methylthioadenosine Phosphorylase (Mtap) In Human Colon Carcinoma Cells Is Regulated By Tcf1/[Beta]-Catenin.
Laboratory Investigation; A Journal Of Technical Methods And Pathology
2019

Microbial Genomic Analysis Reveals the Essential Role of Inflammation in Bacteria-Induced Colorectal Cancer
Nature Communications
2019

The Microbiota Protects Against Ischemia/Reperfusion-Induced Intestinal Injury Through Nucleotide-Binding Oligomerization Domain-Containing Protein 2 (Nod2) Signaling.
The American Journal Of Pathology
2019

Intestinal Inflammation Targets Cancer-Inducing Activity Of The Microbiota.
Science (New York, N.Y.)
2019

Epithelial Cell-Specific Myd88 Signaling Mediates Ischemia/Reperfusion-Induced Intestinal Injury Independent Of Microbial Status.
Inflammatory Bowel Diseases
2019

Regulation And Functional Impact Of Lipopolysaccharide Induced Nod2 Gene Expression In The Murine Epididymal Epithelial Cell Line Pc1.
Immunology
2019

Polymorphism Of Monocyte Chemoattractant Protein 1 In Crohn'S Disease.
International Journal of Colorectal Disease
2019

Lack Of Association Between The Functional Cx3Cr1 Polymorphism V249I And Hepatocellular Carcinoma.
Oncology Reports
2019

Pd-L1 Is Induced In Hepatocytes By Viral Infection And By Interferon-Alpha And -Gamma And Mediates T Cell Apoptosis.
Journal Of Hepatology
2019

Analysis Of Monocyte Chemotactic Protein-1 Gene Polymorphism In Patients With Spontaneous Bacterial Peritonitis.
World Journal of Gastroenterology
2019

Promoter-Hypermethylation Is Causing Functional Relevant Downregulation Of Methylthioadenosine Phosphorylase (Mtap) Expression In Hepatocellular Carcinoma.
Molecular Carcinogenesis
2019

Altered Intestinal Microbiota-Host Mitochondria Crosstalk in New Onset Crohn's Disease
Nature Communications
2019

Research Interests

Research Interest of the Muehlbauer Lab:

  • The overarching goal of our laboratory is the identification of the molecular mechanisms by which commensal bacteria regulate wound healing responses of intestinal stem cells specifically in inflammatory bowel disease, colitis-associated colon cancer and necrotizing enterocolitis. The ultimate long-term clinical and translational research goals are to develop pharmacologic treatments directed at the modulation of the microbiome based on the molecular mechanisms found through our research.
  • To learn more, please visit gastroliver.medicine.ufl.edu/ibd/muehlbauer-research-lab.