Patrick J Antonelli, M.D. - Research & Publications

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Publications

Risk for Tympanic Membrane Perforation after Quinolone Ear Drops for Acute Otitis Externa
Clinical Infectious Diseases
2019

Microbiome Analysis of Cholesteatoma by Gene Sequencing
Otology & Neurotology
2019

Efficacy of the mini-meatoplasty
The Laryngoscope
2019

Commercial Quinolone Ear Drops Cause Perforations in Intact Rat Tympanic Membranes
Otology & Neurotology
2019

Cochlear basal turn patency in unrecognized perilymph gushers
International Journal of Pediatric Otorhinolaryngology
2019

Use of Systemic Antibiotics for Acute Otitis Externa: Impact of a Clinical Practice Guideline.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
2018

Risk of Sudden Sensorineural Hearing Loss in Adults Using Phosphodiesterase Type 5 Inhibitors: Population-Based Cohort Study

2018

Prevention of Chlorhexidine Ototoxicity With Poloxamer in Rats.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
2018

Prevention and Management of Complications in Otosclerosis Surgery
Otolaryngologic clinics of North America
2018

Novel Computed Tomography Findings Suggestive of Perilymph Gusher.
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
2018

Evaluation of Mitoquinone for Protecting Against Amikacin-Induced Ototoxicity in Guinea Pigs
Otology & Neurotology
2018

Efficacy of common reagents for killing ticks in the ear canal
Laryngoscope investigative otolaryngology.
2018

Cytotoxicity of Ciprofloxacin and Steroids in Mouse Tympanic Membrane Fibroblasts
Otolaryngology--head and neck surgery (Online)
2018

Azithromycin and Sensorineural Hearing Loss in Adults: A Retrospective Cohort Study
Otology & Neurotology
2018

Safety and Efficacy of Ebselen for the Prevention of Noise-Induced Hearing Loss: a Randomised, Double-Blind, Placebo-Controlled, Phase 2 Trial
Lancet
2017

Quinolone Ear Drops After Tympanostomy Tubes and the Risk of Eardrum Perforation: a Retrospective Cohort Study

2017

Microflora of Retained Intracochlear Electrodes from Infected Cochlear Implants
Otolaryngology--head and neck surgery (Online)
2017

Randomized Clinical Trial of a Sustained-Exposure Ciprofloxacin for Intratympanic Injection During Tympanostomy Tube Surgery
Annals of Otology Rhinology and Laryngology
2016

Prevention of Biofilm Formation By Polyquaternary Polymer
International Journal of Pediatric Otorhinolaryngology
2016

Magnetic Resonance Imaging in a Guinea Pig Model of Inner Ear Decompression Sickness and Barotrauma
The Laryngoscope
2016

Epidemiology of Persistent Tympanic Membrane Perforations Subsequent to Tympanostomy Tubes Assessed With Real World Data
Otology & Neurotology
2016

Effect of Repeated Tracheostomy Tube Reprocessing on Biofilm Formation
The Laryngoscope
2016

Dietary Supplement Comprised of Beta-Carotene, Vitamin C, Vitamin E, and Magnesium: Failure to Prevent Music-Induced Temporary Threshold Shift
Audiology and Neurotology Extra
2016

Ciprofloxacin Decreases Collagen in Mouse Tympanic Membrane Fibroblasts
Otolaryngology–Head and Neck Surgery
2016

Hydrogel Sutureless Facial Nerve Repair: Pilot Clinical Investigation
The Laryngoscope
2015

Effect of Haemophilus Influenzae Exposure On Staphylococcus Aureus Tympanostomy Tube Attachment and Biofilm Formation
Jama Otolaryngology-Head & Neck Surgery
2015

Assessment of Mitochondrial Membrane Potential in Hei-Oc1 and Llc-Pk1 Cells Treated With Gentamicin and Mitoquinone
Otolaryngology–Head and Neck Surgery
2015

Utilization Pattern of Phosphodiesterase Type 5 (Pde5) Inhibitors for Erectile Dysfunction Among Commercially Insured Adults in the United States

2014

Risk of Sudden Sensorineural Hearing Loss in Adults Using Phosphodiesterase Type 5 Inhibitors

2014

Negative Results Do Not Imply Absence of Ototoxicity With Middle Ear Application of Neomycin
Otolaryngology–Head and Neck Surgery
2014

Mitochondria-Targeted Antioxidant Mitoq Reduces Gentamicin-Induced Ototoxicity
Otology & Neurotology
2014

Association Between Location of Nasopharyngeal Carcinoma, Pre- and Postradiation Therapy Otitis Media With Effusion, and Sensory Neural Hearing Loss
International Journal Of Radiation Oncology Biology Physics
2014

Sensorineural Hearing Loss Associated With Neomycin Eardrops and Nonintact Tympanic Membranes
Otolaryngology–Head and Neck Surgery
2013

Response To Letter To the Editor Regarding Sensorineural Hearing Loss Associated With Neomycin Eardrops and Nonintact Tympanic Membranes
Otolaryngology–Head and Neck Surgery
2013

Microbial Flora of Cochlear Implants By Gene Pyrosequencing
Otology & Neurotology
2013

Efficacy of Disinfecting Solutions in Removing Biofilms From Polyvinyl Chloride Tracheostomy Tubes
The Laryngoscope
2013

Development of a Novel Ex Vivo Porcine Skin Explant Model for the Assessment of Mature Bacterial Biofilms

2013

Biofilm Formation On Coated Silicone Tympanostomy Tubes
International Journal of Pediatric Otorhinolaryngology
2013

Tympanostomy Tube in Vitro Biofilm Potential of Common Otopathogens
Otolaryngology–Head and Neck Surgery
2012

Prevention of Gentamicin-Induced Apoptosis With the Mitochondria-Targeted Antioxidant Mitoquinone
The Laryngoscope
2012

Postradiation Otitis Media With Effusion: Modeling the Complication Probability and Determining the Parameters of Clinical Significance
International Journal Of Radiation Oncology Biology Physics
2012

Ototopical Neomycin Exposure in Children With Nonintact Tympanic Membranes
The Laryngoscope
2012

Evaluating the Association Between Pre- and Postradiation Therapy Otitis Media With Effusion and the Incidence of Sensory-Neural Hearing Loss in Head-And-Neck Cancer Patients
International Journal Of Radiation Oncology Biology Physics
2012

Endolymphatic Hydrops Perspectives 2012
Current Opinion in Otolaryngology & Head and Neck Surgery
2012

Effectiveness of Pediatric Tracheostomy Tube Cleaning
Archives of Otolaryngology-Head & Neck Surgery
2012

Effect of Tympanostomy Tube Surface On Occlusion
International Journal of Pediatric Otorhinolaryngology
2012

Digital Music Exposure Reliably Induces Temporary Threshold Shift in Normal-Hearing Human Subjects
Ear and Hearing
2012

Audiology in the Sudden Hearing Loss Clinical Trial
The American Journal of Otology
2012

Aminoglycoside Eardrops and Risk of Sensorineural Hearing Loss in Children With Non-Intact Tympanic Membranes

2012

Topical Antibiotic Treatment Reduces Tympanostomy Tube Biofilm Formation
The Laryngoscope
2011

Pseudomonas Biofilm Formation After Haemophilus Infection
Otolaryngology–Head and Neck Surgery
2011

Prospective Clinical Trial Comparing Outcome Measures Between Furlow and Von Langenbeck Palatoplasties for Uclp
Annals of Plastic Surgery
2011

Otologic and Audiologic Outcomes With the Furlow and Von Langenbeck With Intravelar Veloplasty Palatoplasties in Unilateral Cleft Lip and Palate
Cleft Palate-Craniofacial Journal
2011

Oral Vs Intratympanic Corticosteroid Therapy for Idiopathic Sudden Sensorineural Hearing Loss a Randomized Trial
Jama-Journal of the American Medical Association
2011

Failure of Fluorescence To Reveal Middle Ear Penetration of Quinolone Drops
Archives of Otolaryngology-Head & Neck Surgery
2011

Biofilm Formation On Silicone Tympanostomy Tubes With Polyvinylpyrrolidone Coating
Archives of Otolaryngology-Head & Neck Surgery
2011

Topical dexamethasone and tympanic membrane perforation healing in otitis media: a short-term study.
The American Journal of Otology
2010

Topical Dexamethasone and Tympanic Membrane Perforation Healing in Otitis Media: a Short-Term Study
The American Journal of Otology
2010

Safety and Efficacy of Carbomethylcellulose Foam in Guinea Pig Middle Ear Surgery
Otolaryngology–Head and Neck Surgery
2010

Radiation Therapy and Hearing Loss
International Journal Of Radiation Oncology Biology Physics
2010

Perioperative Medication Errors in Otolaryngology
The Laryngoscope
2010

Errors in the Diagnosis and Management of Necrotizing Otitis Externa
Otolaryngology–Head and Neck Surgery
2010

Development of a Calcium Alginate Tympanostomy Tube
The Laryngoscope
2010

Am-111 Prevents Hearing Loss From Semicircular Canal Injury in Otitis Media
The Laryngoscope
2010

Radiation Effects On the Auditory and Vestibular Systems
Otolaryngologic clinics of North America
2009

Oral Disinhibition Varies With Taster Status: Unilateral Anterior Oral Anesthesia Produces Asymmetric Posterior Taste Loss in Nontasters
Chemical Senses
2009

Longitudinal Study of Growth of Children With Unilateral Cleft-Lip Palate From Birth To Two Years of Age
Cleft Palate-Craniofacial Journal
2009

In Vitro Testing of Tympanostomy Tube Occlusion
Otolaryngology–Head and Neck Surgery
2009

Effect of Ossicular Prosthesis Biofilms On Middle Ear Scarring and Hearing Outcomes
The American Journal of Otology
2009

Cochlear nerve diameter in normal hearing ears using high-resolution magnetic resonance imaging.
The Laryngoscope
2009

Cochlear Nerve Diameter in Normal Hearing Ears Using High-Resolution Magnetic Resonance Imaging
The Laryngoscope
2009

Biofilm Formation By Pseudomonas Aeruginosa On Ossicular Reconstruction Prostheses
American Journal of Otolaryngology
2009

Effect of Blood and Mucus On Tympanostomy Tube Biofilm Formation
The Laryngoscope
2008

Alpha1-antitrypsin single dose adjuvant therapy for acute otitis media.
Otolaryngology–Head and Neck Surgery
2006

Inflammatory proteases in chronic otitis externa.
The Laryngoscope
2005

Gastric reflux is uncommon in acute post-tympanostomy otorrhea.
Otolaryngology–Head and Neck Surgery
2005

Bacterial biofilms may contribute to persistent cochlear implant infection.
The American Journal of Otology
2004

An outer hair cell of the inner ear.
Nature cell biology
2004

Protease inhibitors alpha1-antitrypsin and ilomastat are not ototoxic in the chinchilla.
The Laryngoscope
2003

Alpha 1-antitrypsin and ilomastat inhibit inflammatory proteases present in human middle ear effusions.
The Laryngoscope
2003

Fetal central auditory system metabolic response to cochlear implant stimulation.
Otolaryngology–Head and Neck Surgery
2002

Computerized physician-order entry: are we there yet?
Otolaryngologic clinics of North America
2002

Treatment of paragangliomas with radiation therapy.
Otolaryngologic clinics of North America
2001

Radiotherapy and radiosurgery for skull base tumors.
Otolaryngologic clinics of North America
2001

Hearing preservation with labyrinthine ablation in otitis media.
The Laryngoscope
2000

Diagnostic yield of high-resolution computed tomography for pediatric sensorineural hearing loss.
The Laryngoscope
1999

Vestibular caloric responses and behavioral state in the fetal sheep.
International Journal of Pediatric Otorhinolaryngology
1998

Research Interests

  • Prevention of biofilms on otologic implants
  • Prevention of tympanostomy tube occlusion
  • Prevention of hearing loss from iatrogenic injury and noise
  • Medical errors