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Research Firsts

UF Health Science Center 


UF’s most well-known invention has been quenching thirst and drenching coaches’ heads since 1965.


Discovered at UF, this breakthrough drug safely treats the blinding eye disease glaucoma and is relatively free of the side effects associated with other standard glaucoma drugs.

Adeno-associated virus

Apparently harmless to humans, this virus is used to transport genes that correct hereditary defects in people. UF researchers pioneered AAV, which is used worldwide and is considered one of the safest gene therapy vectors.

Human Patient Simulator

This UF-invented artificial patient looks and responds just as a living patient would to trauma or treatment, and has revolutionized clinical training for the treatment of critical illnesses or injuries.


Periodontal disease can lead to a loss of supporting tissue around teeth and even to bone loss in the jaw. This bioactive glass developed at UF helps restore bone and tissue loss due to gum disease.

Smart House

This techno-home, which uses technology to help the elderly overcome their limitations and to evaluate their driving skills, was created by UF researchers and engineers.


This alarm system developed at UF in collaboration with Honeywell helps caregivers of people with Alzheimer’s and other forms of dementia safely monitor loved ones.


This infusion needle is used to inject fluids or drugs directly into the bones of children when a regular intravenous infusion is too difficult.

Microbicidal bandage

While trying to build a better bandage, UF researchers developed a coating that kills dangerous antibiotic-resistant bacteria.

Skin grafts

Lab-grown skin grafts for burn victims were first developed by a UF researcher.

Prevention therapy

A UF researcher developed a genetically engineered germ that could provide lifelong protection from cavities.

HIV saliva test

UF veterinary neurologist developed a saliva test for HIV that gives results in 15 minutes.

Diabetes test

College of Medicine researchers discovered a way to test for insulin-dependent diabetes years before symptoms appear.

Nasal flu vaccine

Two UF researchers were the first to introduce the idea of a nasally administered flu vaccine, leading the way to nasal flu vaccines on the market today.

LINAC Scalpel

Researchers at UF developed the UF Radiosurgery System, also known as the LINAC Scalpel, to produce a 10-fold improvement in the accuracy of radiation delivered to brain tumors.