A Randomized Phase III Clinical Trial Evaluating Post-mastectomy chestwall and Regional Nodal and Post-lumpectomy Regional Nodal XRT In Patients With Positive Axillary Nodes Before Neoadjuvant Chemotherapy Who Convert To Pathologically Negative

Purpose

This randomized phase III trial studies standard or comprehensive radiation therapy in treating patients with early-stage breast cancer who have undergone surgery. Radiation therapy uses high-energy x rays to kill tumor cells. It is not yet known whether comprehensive radiation therapy is more effective than standard radiation therapy in treating patients with breast cancer.

Primary Outcome Measure:

  1. IBC-RFI [ Time Frame: Time from randomization until invasive local, regional, or distant recurrence, or death from breast cancer, assessed up to 10 years ]

Age

18 to 65
65 and over

Gender

Female

Monetary compensation

No

Can be done from home

No

Principal Investigator

Paul Okunieff, M.D.

Sponsoring Group

Department of Radiation Oncology

Department

Department of Radiation Oncology

Contact Information

pokunieff@ufl.edu

352.265.0287


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