Biomarkers in Friedreich’s Ataxia

Purpose

The purpose of this research study is to find out what the best tests and evaluations are for measuring the effects of Friedreich’s ataxia on the body, to help us to design clinical trials.

Procedures

You will be asked to complete a variety of tests to measure your muscle function, your brain function, and your heart function. This testing will occur over the course of 1 to 2 days, and you may be asked to repeat some tests over those 2 days in order to see if they give the same results.

Eligibility

  • 8-70 years old
  • Genetic diagnosis of Friedreich's ataxia by DNA sequencing, mutational analysis or protein assay OR be a healthy subject with no evidence of a neuromuscular disorder
  • Are able to tolerate metabolic exercise testing
  • Are stable on cardiac medication regimen for 3 months prior to screening

For additional study information, please contact Samatha Norman: 

Age

18 and under
18 to 65
65 and over

Gender

Male
Female

Monetary compensation

No

Can be done from home

No

Keywords

Friedreich's ataxia, Friedreich ataxia, Neurology, healthy volunteers

Principal Investigator

Manuela Corti, PT, PhD

Department

Neurology

Contact Information

samantha.norman@peds.ufl.edu

(352) 273-8218


Be an Informed Participant

Before deciding to participate in a research study, take time to learn about clinical research, how it's conducted and your rights as a research participant. Following are some helpful resources from independent sources. Always remember that a clinical research study is research, not treatment.

Know Who to Contact

  • Eligibility: For questions about a specific study and who is eligible to participate, call or email the contact person listed for that study.
  • Your Rights: For questions about your rights as a research participant, contact the UF Institutional Review Boards at 352-273-9600.
  • Feedback: For general questions or feedback about study listings, email the UF Clinical and Translational Science Institute at CTSI-Studies-L@lists.ufl.edu.

Other Resources

  • HealthStreet: Health-focused services, classes and events, and opportunities to participate in research.
  • ResearchMatch.org: Join a national registry of volunteers willing to be contacted about research studies.

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