Brain imaging and Social cognition in myotonic dystrophy (DM) type 1

Purpose

This study is designed to assess social cognition deficits in adult onset patients with myotonic dystrophy type 1 and understand possible neuroimaging correlates of such deficits.

Procedures

  • Cognitive studies including measurements for empathy and social behavioral abnormalities 
  • Heart rate and blood sample
  • Imaging studies including MRI

For more details about study procedures, please contact Stephen Gullet:

Eligibility 

  • Over 18 years old 
  • Molecularly confirmed DM 1 (symptomatic subjects in whom diagnosis is based on DNA analysis in affected family members will also qualify)
  • MOCA score > 22
  • Competent and willing to provide informed consent and participate in study procedures
  • Controls for cognition and imaging studies will be recruited from among spouses or other unaffected family members of DM1 patients and if needed, from among non-family members who are deemed to have no significant and uncontrolled neurological or systemic disorders.

Additional criteria apply, for more information please contact Stephen Gullet:

Age

18 to 65
65 and over

Gender

Male
Female

Can be done from home

No

Keywords

Muscular dystrophy, Muscular dystrophy - resources, Neurology

Principal Investigator

S.H. Subramony, MD

Department

Neurology

Contact Information

stephen.gullett@neurology.ufl.edu

352-273-6003


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