Dual Lead Thalamic DBR-DBS Interface for Closed Loop Control of Severe Essential Tremor

Purpose

The purpose of this research study is to test the effectiveness of Responsive Deep Brain Stimulation (R-DBS) for Essential Tremor (ET). Current DBS therapy for ET leaves the device on all of the time, even when you do not have tremor. With R-DBS, the device will only turn on when you make certain movements that lead to tremor.

Continuous DBS can lead to undesirable side effects such as stuttering, walking/balance problems. R-DBS will turn on only in response to a signal in your brain prior to and during tremor, and therefore the DBS will not be on all of the time.

The device actually has the potential to see a brain signal change associated with your tremor less than a second before the tremor occurs. We hope that R-DBS will provide the same benefit with fewer side effects. We believe that R-DBS may also prolong the battery life of your implant.

Eligibility

  • Healthy patients with severe, debilitating intention tremor
  • Healthy patients with recurring intention tremor despite ongoing, optimized VIM DBS therapy

For additional study details and eligibility criteria, please contact Rebeca Castro:

Age

18 to 65

Gender

Male
Female

Monetary compensation

Yes

Can be done from home

No

Keywords

Essential tremor, Essential Tremors

Principal Investigator

Karim Oweiss, PhD

Department

Engineering

Contact Information

rcastro4@ufl.edu

(352) 294-0486


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