Effect of Chemotherapy on Spermatogenesis / Steroidogenesis in Young Osteosarcoma Survivors


This research trial studies saliva, semen, and blood samples to determine effects of chemotherapy on fertility in osteosarcoma survivors. Study biospecimen samples from osteosarcoma survivors in the laboratory may help doctors learn whether chemotherapy causes fertility problems and to learn more about the long term effects.


  • Ages: 18 years to 50 years
  • Sexes: Male
  • Accepts healthy volunteers?: No

For additional eligibility criteria. please contact the study team.


  • Biospecimen Collection: Undergo collection of blood and provide saliva and semen samples.
  • Laboratory Biomarker Analysis (correlative studies)
  • Questionnaire administration: Ancillary studies

Contact the study team

Additional eligibility criteria and study procedure details can be explained by the study team. Please call or email:

  • Phone: 352.273.8675
  • Email: trials@cancer.ufl.edu


18 to 65




Cancer, Osteosarcoma, Chemotherapy, Infertility

Principal Investigator

Margarett Shnorhavorian, MD



Contact Information



Be an Informed Participant

Before deciding to participate in a research study, take time to learn about clinical research, how it's conducted and your rights as a research participant. Following are some helpful resources from independent sources. Always remember that a clinical research study is research, not treatment.

Know Who to Contact

  • Eligibility: For questions about a specific study and who is eligible to participate, call or email the contact person listed for that study.
  • Your Rights: For questions about your rights as a research participant, contact the UF Institutional Review Boards at 352-273-9600.
  • Feedback: For general questions or feedback about study listings, email the UF Clinical and Translational Science Institute at CTSI-Studies-L@lists.ufl.edu.

Other Resources

  • HealthStreet: Health-focused services, classes and events, and opportunities to participate in research.
  • ResearchMatch.org: Join a national registry of volunteers willing to be contacted about research studies.

For Research Teams