Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS
The purpose of this study is to investigate the effects of two treatment techniques called Expiratory Muscle Strength Training (EMST) and Lung Volume Recruitment (LVR) on breathing, swallowing, speech, and cough function in persons with mild to moderate ALS. Half of the participants will do EMST alone, and the other half of the participants will do EMST and LVR.
- Expiratory Muscle Strength Training (EMST) uses a training device that has a valve set to 50% of a patient's maximum expiratory pressure (MEP). The patient exhales forcefully until the valve releases. Patients perform 5 sets of 5 repetitions a day, 5 days a week.
- Lung Volume Recruitment (LVR) is a technique to increase cough function that is performed with a resuscitation bag fitted with a mouthpiece and a one-way valve. The bag is used to expand the lungs, after which the patient makes a voluntary cough. Half of the participants will perform the LVR technique in addition to the ESMT technique.
For more details about study procedures, please contact Kelby Magennis:
- ALS defined as possible, laboratory-supported probable, probable, or definite by El Escorial criteria
- Reduced Maximal Expiratory Pressure (MEP) compared to norms for age and sex
- Forced Vital Capacity (FVC) > 65% predicted
Additional inclusion and exclusion criteria apply. Please contact Kelby Magennis:
Can be done from home
KeywordsNeurology, Amyotrophic lateral sclerosis, ALS - resources, ALS
Principal InvestigatorEmily Plowman, PhD, CCC-SLP
Begin a new search for other research studies
Studies listed on this site have been approved by a UF Institutional Review Board (IRB), which works to ensure the welfare and rights of research participants as required by federal regulations. Study listings are provided by the UF Clinical and Translational Science Institute in collaboration with UF research teams and the UF IRBs.