All results

6 results for standard dose combination chemotherapy or high dose combination chemotherapy and stem

• Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid

  This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal…

  Ages

  18 Years - N/A

  Sexes

  All

• Phase 2 Study to evaluate Pembrolizumab Plus Lenvatinib in Combo w/ Belzutifan in Solid Tumors

  The purpose of this study is to determine the safety and efficacy of belzutifan in combination with pembrolizumab and lenvatinib in multiple solid tumors…

  Ages

  18 Years - N/A

  Sexes

  All

• Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

  This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering…

  Ages

  12 Months - 21 Years

  Sexes

  All

• Addition of Pembrolizumab to Usual Intravesical Gemcitabine for Treatment of BCG-Unresponsive NMIBC

  This phase II trial studies the effect of adding pembrolizumab to gemcitabine in treating patients with non-muscle invasive bladder cancer whose cancer does…

  Ages

  18 Years - N/A

  Sexes

  All

• Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy for Limited mCRC(ERASur)

  This phase III trial compares total ablative therapy and usual systemic therapy to usual systemic therapy alone in treating patients with colorectal cancer…

  Ages

  18 Years - N/A

  Sexes

  All

• Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease (CIRCULATE-US)

  This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA)…

  Ages

  18 Years - N/A

  Sexes

  All