Sam Cheng, M.D.

Sam Cheng, M.D.

(352) 273-9350

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Publications

Gastric electrical stimulation: An emerging therapy for children with intractable gastroparesis.
World journal of gastroenterology
2019

Inability to reduce morbidity of diarrhea by ORS: can we design a better therapy?
Pediatric research
2018

Extracellular Calcium Dictates Onset, Severity, and Recovery of Diarrhea in a Child with Immune-Mediated Enteropathy.
Frontiers in pediatrics
2018

Calcimimetic acts on enteric neuronal CaSR to reverse cholera toxin-induced intestinal electrolyte secretion.
Scientific reports
2018

Calcimimetic R568 inhibits tetrodotoxin-sensitive colonic electrolyte secretion and reduces c-fos expression in myenteric neurons.
Life sciences
2018

Bumetanide increases Cl--dependent short-circuit current in late distal colon: Evidence for the presence of active electrogenic Cl- absorption.
PloS one
2017

The role of the calcium-sensing receptor in gastrointestinal inflammation.
Seminars in cell & developmental biology
2016

The Extracellular Calcium-Sensing Receptor in the Intestine: Evidence for Regulation of Colonic Absorption, Secretion, Motility, and Immunity.
Frontiers in physiology
2016

Corrigendum: The Extracellular Calcium-Sensing Receptor in the Intestine: Evidence for Regulation of Colonic Absorption, Secretion, Motility, and Immunity.
Frontiers in physiology
2016

Calcium-sensing receptor: A new target for therapy of diarrhea.
World journal of gastroenterology
2016

Calcium-sensing receptor stimulates Cl(-)- and SCFA-dependent but inhibits cAMP-dependent HCO3(-) secretion in colon.
American journal of physiology. Gastrointestinal and liver physiology
2015

Epithelial CaSR deficiency alters intestinal integrity and promotes proinflammatory immune responses.
FEBS letters
2014

Colonic immune suppression, barrier dysfunction, and dysbiosis by gastrointestinal bacillus anthracis Infection.
PloS one
2014

Calcium-Sensing Receptor in Ens: a Mechanism To Inhibit Enteric Nerve Activity and Reduce Diarrhea
Neurogastroenterology and Motility
2014

Celiac disease in a child with ulcerative colitis: a possible genetic association.
Journal of clinical gastroenterology
2013

Calcium ameliorates diarrhea in immunocompromised children.
Journal of pediatric gastroenterology and nutrition
2013

Calcium-sensing receptor inhibits secretagogue-induced electrolyte secretion by intestine via the enteric nervous system.
American journal of physiology. Gastrointestinal and liver physiology
2012

Jejunal adaptation in a prepubertal boy after total ileal resection and jejunostomy placement: a four-year follow-up.
Journal of clinical gastroenterology
2011

WNK4 regulates activity of the epithelial Na+ channel in vitro and in vivo.
Proceedings of the National Academy of Sciences of the United States of America
2007

Calcium-sensing receptor abrogates secretagogue- induced increases in intestinal net fluid secretion by enhancing cyclic nucleotide destruction.
Proceedings of the National Academy of Sciences of the United States of America
2006

The calcium-sensing receptor acts as a modulator of gastric acid secretion in freshly isolated human gastric glands.
American journal of physiology. Gastrointestinal and liver physiology
2005

Functions and roles of the extracellular Ca2+-sensing receptor in the gastrointestinal tract.
Cell calcium
2004

Extracellular polyamines regulate fluid secretion in rat colonic crypts via the extracellular calcium-sensing receptor.
Gastroenterology
2004

Mechanisms of Na+-K+-ATPase phosphorylation by PKC in the medullary thick ascending limb of Henle in the rat.
Pflugers Archiv : European journal of physiology
2003

Intracellular sodium modulates the state of protein kinase C phosphorylation of rat proximal tubule Na+,K+-ATPase.
Acta physiologica Scandinavica
2002

Expression of calcium-sensing receptor in rat colonic epithelium: evidence for modulation of fluid secretion.
American journal of physiology. Gastrointestinal and liver physiology
2002

Combined antioxidant and COMT inhibitor treatment reverses renal abnormalities in diabetic rats.
Diabetes
2000

[Ca2+]i determines the effects of protein kinases A and C on activity of rat renal Na+,K+-ATPase.
The Journal of physiology
1999

Forskolin-induced down-regulation of Na+,K(+)-ATPase activity is not associated with internalization of the enzyme.
Acta physiologica Scandinavica
1998

Effects of okadaic acid, calyculin A, and PDBu on state of phosphorylation of rat renal Na+-K+-ATPase.
The American journal of physiology
1998

Regulation of rat Na(+)-K(+)-ATPase activity by PKC is modulated by state of phosphorylation of Ser-943 by PKA.
The American journal of physiology
1997

PKA-mediated phosphorylation and inhibition of Na(+)-K(+)-ATPase in response to beta-adrenergic hormone.
The American journal of physiology
1997

20-Hydroxyeicosa-tetraenoic acid (20 HETE) activates protein kinase C. Role in regulation of rat renal Na+,K+-ATPase.
The Journal of clinical investigation
1997

Cellular mechanisms for bi-directional regulation of tubular sodium reabsorption.
Kidney international
1996

Identification of the phosphorylation site for cAMP-dependent protein kinase on Na+,K(+)-ATPase and effects of site-directed mutagenesis.
The Journal of biological chemistry
1994

Molecular mechanisms in Angelman syndrome: a survey of 93 patients.
Journal of medical genetics
1993

Duplication of chromosome 15 in the region 15q11-13 in a patient with developmental delay and ataxia with similarities to Angelman syndrome.
Journal of medical genetics
1993

Further evidence for dominant inheritance at the chromosome 15q11-13 locus in familial Angelman syndrome.
American journal of medical genetics
1992

Angelman syndrome with a chromosomal inversion 15 inv(p11q13) accompanied by a deletion in 15q11q13.
Journal of medical genetics
1992

Study on immunopathogenesis of minimal change nephropathy. Effects of mitogens activated lymphocytes on glomerular polyanions in vitro.
Chinese medical journal
1989

[Effects of mitogen-activated lymphocytes on glomerular polyanion (GPA) in rats].
Zhonghua yi xue za zhi
1988