Systemic: Research Studies

116 Related Result(s)

  1. A Randomized, Blinded Study of Fluorescence Detection of Pediatric Primary Central Nervous System Tumors in Subjects Receiving Tozuleristide and Imaged with the Canvas System

    The main goal of this efficacy study is to learn how well tozuleristide and the Canvas work at detecting tumors during surgery. This study will also look at...

  2. (HeadStart 4) Newly Diagnosed Children (Less than 10 Years Old) With Medulloblastoma and Other Central Nervous System Primitive Neuro-Ectodermal Tumors: Clinical and Molecular Risk-Tailored Intensive and Compressed Induction Chemotherapy Followed by Consolidation with Either Single-Cycle (Low Risk Patients) or Randomization (High Risk Patients) to either Single-Cycle or to Three Tandem Cycles of Marrow-Ablative Chemotherapy with Autologous Hematopoietic Progenitor Cell Rescue

    This research study will compare two different treatment regimens to see which is better for treating children with different types of brain tumors called...

  3. System Dynamics Modeling of Multi-Level Coping Responses to Understand Resilience

    The purpose is this study is to use system dynamics modeling to study the problem of crowding at emergency department (ED) and hospital. The researcher will...

  4. A Phase 3 Randomized, Open-Label Study Comparing Pexa-Vec (Vaccinia GM-CSF/Thymidine Kinase-Deactivated Virus) Followed by Sorafenib Versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC) Without Prior Systemic Therapy

    The primary objective is to determine and compare the overall survival of patients with advanced Hepatocellular Carcinoma or liver cancer, without prior...

  5. Zenith Dissection Endovascular System in the Treatment of Patients With Aortic Dissections

    The Zenith Dissection extended...

  6. Zenith Dissection Endovascular System in the Treatment of Patients with Aortic Dissections

    The purpose is to study the safety and effectiveness of the Zenith Dissection Endovascular System in the treatment of acute, complicated Type B aortic...

  7. A Phase III Randomized, Open Label, Multi-center Study of the Safety and Efficacy of Apixaban for Thromboembolism Prevention Versus No Systemic Anticoagulant Prophylaxis During Induction Chemotherapy in Children With Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) or Lymphoma (T or B Cell) Treated With Asparaginase

    The purpose of this study is to compare the effect of a blood thinning drug called Apixaban versus no administration of a blood thinning drug, in preventing...

  8. Efficacy and Safety of Rivaroxaban Prophylaxis Compared with Placebo in Ambulatory Cancer Patients Initiating Systemic Cancer Therapy and at High Risk for Venous Thromboembolism

    The primary efficacy objective is to demonstrate that rivaroxaban is superior to placebo for reducing the risk of the primary composite outcome as defined by...

  9. PNOC-013: A Safety and Pharmacokinetic Study of Single Agent REGN2810 in Pediatric Patients with Relapsed or Refractory Solid or Central Nervous System (CNS) Tumors and a Safety and Efficacy Trial of REGN2810 in Combination with Radiotherapy in Pediatric Patients with Newly Diagnosed Diffuse Intrinsic Pontine Glioma, Newly Diagnosed High-Grade Glioma, or Recurrent High-Grade Glioma

    This study is being done to test if cemiplimab-rwlc (“study drug”) can reduce the size of your tumor by helping the immune system destroy the tumor. The...

  10. (PRECISION) A Phase II Study of the Optune System, Enhanced by Genomic Analysis to Identify the Genetic Signature of Response in the Treatment of Recurrent Glioblastoma Multiforme

    The purpose of this research study is to collect information on how people respond to treatment with Optune and to see if their response to treatment relates...

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