UF Health Shands Comprehensive Stroke Center: Clinical Trials
Stroke research is a vital component for patients at the UF Health Shands Comprehensive Stroke Center.
UF Health Stroke Clinical Trials
(Atrial Cardiopathy and Antithrombotic Drugs in Prevention After Cryptogenic Stroke)
Trial of apixaban versus aspirin in patients who have evidence of atrial cardiopathy and a recent stroke of unknown cause
(Cognition and Silent Infarcts)
Compare the effects of ARCADIA study drugs on the occurrence of silent strokes and memory loss after stroke.
Antithrombotic treatment with factor XIa inhibition to Optimize Management of Acute Thromboembolic events in Secondary Stroke Prevention. A Global, Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Study of BMS-986177, an Oral Factor XIa Inhibitor, for the Prevention of New Ischemic Stroke or New Covert Brain Infarction in Patients Receiving Aspirin and Clopidogrel Following Acute Ischemic Stroke or Transient Ischemic Attack (TIA)
(Glibenclamide for Large Hemispheric Infarction (LHI) Analyzing mRS and Mortality)
To evaluate the efficacy and safety of intravenous Glibenclamide for severe cerebral edema following large hemispheric infarction
- CREST-2 + Registry
(Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial)
To assess treatment differences between intensive medical management alone compared to CEA/CAS plus intensive medical management
- CREST – H
(Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis - Hemodynamics)
To determine whether cognition can be improved by revascularization among patients with hemodynamic impairment and mild cognitive impairment at baseline
(Hispanic Stroke Prevention/Intervention Research Program)
Evaluate the disparities in stroke performance metrics individually and for overall rates by race, ethnicity, and geographic region in Florida and Puerto Rico
(Multi-arm Optimization of Stroke Thrombolysis)
A blinded, randomized controlled adaptive, multi-arm, adjunctive-thrombolysis efficacy trial in ischemic stroke
(Sleep for Stroke Management And Recovery Trial)
To test whether treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure is effective for secondary prevention and recovery after stroke.
(Statins Use in Intracerebral Hemorrhage Patients)
A Phase III study to determine the risk of statin use after an intracerebral hemorrhage (ICH) on ICH reoccurrence or new occurrence of any other major cerebrovascular event.
(Transitions of Care Stroke Disparity Study)
Focuses on identifying race-ethnic and sex disparities in hospital-to-home transition of care and outcomes after stroke.
(Impact of Fever Prevention in Brain Injured Patients)
To assess fever burden and the impact on outcomes of fever prevention in brain-injured patients
(ExtracorPoreal FILtration of Subarachnoid Hemorrhage via SpinaL CAtheteR EXTension)
To further demonstrate safety and characterize effectiveness of the Neurapheresis System (extracorporeal system and catheter)
Embolization of the Middle Meningeal Artery with ONYX™ Liquid Embolic System In the Treatment of Subacute and Chronic Subdural HEmatoma
- Sterling Coil Registry
A prospective, multi-center, single arm study to obtain "Real World" clinical data and characterized the acute and long-term performance of the micrusframe and galaxy coils for the endovascular treatment of intracranial aneurysms