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Indoor Rowing as Therapy for Cardiovascular Rehabilitation in Breast Cancer Survivors

  • Status
    Accepting Candidates
  • Age
    40 Years - 80 Years
  • Sexes
  • Healthy Volunteers


There are more than 3.8 million breast cancer survivors in the United States and cancer survivors have a higher risk of cardiovascular disease (CVD) due to chemotherapy than adults without cancer. Cardiovascular rehabilitation can be an effective strategy to decrease the incidence of CVD and its risk factors in this population. The proposed study may help to examine the effect of a novel exercise intervention on cardiovascular rehabilitation in breast cancer survivors.


Full study title Indoor Rowing as a Novel Exercise Therapy for Cardiovascular Rehabilitation in Middle-Aged and Older Breast Cancer Survivors Following Chemotherapy
Protocol number OCR42911 ID NCT05848141
Phase N/A


Inclusion Criteria:

  • diagnosis of primary invasive non-metastatic breast cancer, stages I-III

  • female based on biological sex

  • 40 to 80 years of age

  • completed chemotherapy 6 to 18 months prior to study enrollment

  • absence of contraindications to exercise or study participation

  • study clinician approval

Exclusion Criteria:

  • do not meet inclusion criteria

  • completed chemotherapy and/or other cancer treatment (i.e., surgery or radiation) within past 6 months. Adjuvant endocrine therapy for breast cancer (e.g., ovarian suppression, SERMs, SERDs, AIs), CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed within past 6 months.

  • receiving or scheduled to receive radiation therapy during study participation

  • scheduled to receive surgery during study participation

  • receiving or scheduled to receive chemotherapy during study participation is not allowed. Adjuvant endocrine therapy, CDK4/6 inhibitors, PARP inhibitors, HER2 targeted agents, immunotherapy and bisphosphonates are allowed during study participation.

  • lymphedema stage ≥ 2 prior to study enrolment

  • any relevant cardiovascular diseases (stroke, heart failure, myocardial ischemia during maximal graded exercise test, myocardial infarction, angina pectoris, coronary artery bypass surgery or angioplasty or coronary stent)

  • body mass index ≥ 40 kg/m2

  • current participation in other experimental interventions that may confound interpretation of study findings (e.g., dietary intervention for weight loss)

  • consistent participation in ≥150 min/week of moderate-intensity aerobic exercise training in previous 6 months

Participate in a study

Here are some general steps to consider when participating in a research study:

  1. Step

    Contact the research team

    Call or email the research team listed within the specific clinical trial or study to let them know that you're interested. A member of the research team, such as the researcher or study coordinator, will be available to tell you more about the study and to answer any questions or concerns you may have.

    Primary contact

    Demetra Christou
  2. Step

    Get screened to confirm eligibility

    You may be asked to take part in prescreening to make sure you are eligible for a study. The prescreening process ensures it is safe for you to participate. During the prescreening process, you will be asked some questions and you may also be asked to schedule tests or procedures to confirm your eligibility.

  3. Step

    Provide your consent to participate

    If you are eligible and want to join the clinical trial or study, a member of the research team will ask for your consent to participate. To give consent, you will be asked to read and sign a consent form for the study. This consent form explains the study's purpose, procedures, risks, benefits and provides other important information, such as the study team's contact information.

  4. Step


    If you decide to participate in a clinical trial or study, the research team will keep you informed of the study requirements and what you will need to do to throughout the study. For some trials or studies, your health care provider may work with the research team to ensure there are no conflicts with other medications or treatments.