Duane A Mitchell, M.D., Ph.D.

(352) 273-6990

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Publications

Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+ myeloid cells into the tumor microenvironment in a redundant manner

Oral IRAK-4 Inhibitor CA-4948 Is Blood-Brain Barrier Penetrant and Has Single-Agent Activity against CNS Lymphoma and Melanoma Brain Metastases
Clinical Cancer Research
2023

Cellular Cancer Immunotherapy Development and Manufacturing in the Clinic
Clinical Cancer Research
2023

The current landscape of immunotherapy for pediatric brain tumors.
Nature cancer
2022

Effects of immune checkpoint blockade on antigen-specific CD8+ T cells for use in adoptive cellular therapy.
Microbiology and immunology
2022

Contemporary RNA Therapeutics for Glioblastoma.
Neuromolecular medicine
2022

CAR T Cell Locomotion in Solid Tumor Microenvironment.
Cells
2022

Vaccine Therapies for Cancer: Then and Now.
Targeted oncology
2021

Unique challenges for glioblastoma immunotherapy-discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank.
Neuro-oncology
2021

Tracking adoptive T cell immunotherapy using magnetic particle imaging.
Nanotheranostics
2021

Precision therapeutic targets for COVID-19.
Virology journal
2021

Phase 1 study of pomalidomide in children with recurrent, refractory, and progressive central nervous system tumors: A Pediatric Brain Tumor Consortium trial.
Pediatric blood & cancer
2021

Optimizing T Cell-Based Therapy for Glioblastoma.
Frontiers in immunology
2021

Nanoparticles as immunomodulators and translational agents in brain tumors.
Journal of neuro-oncology
2021

Metabolomics Monitoring of Treatment Response to Brain Tumor Immunotherapy.
Frontiers in oncology
2021

Canine osteosarcoma checkpoint expression correlates with metastasis and T-cell infiltrate.
Veterinary immunology and immunopathology
2021

Adult precision medicine: learning from the past to enhance the future.
Neuro-oncology advances
2021

A vaccine for glioma.
Nature cancer
2021

Therapeutic modulation of phagocytosis in glioblastoma can activate both innate and adaptive antitumour immunity.
Nature communications
2020

RNA-electroporated T cells for cancer immunotherapy.
Oncoimmunology
2020

Once, Twice, Three Times a Finding: Reproducibility of Dendritic Cell Vaccine Trials Targeting Cytomegalovirus in Glioblastoma
Clinical Cancer Research
2020

Immune Escape After Adoptive T-cell Therapy for Malignant Gliomas
Clinical Cancer Research
2020

Dysregulation of Glutamate Transport Enhances Treg Function That Promotes VEGF Blockade Resistance in Glioblastoma
Cancer Research
2020

CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas.
Proceedings of the National Academy of Sciences of the United States of America
2020

Adult immuno-oncology: using past failures to inform the future.
Neuro-oncology
2020

UNLOCKING CANCER IMMUNOTHERAPY AGAINST PEDIATRIC BRAIN TUMORS WITH TRANSCRIPTOME LOADED NANOPARTICLES: IMMU-08
Neuro-Oncology
2019

The role of CMV in glioblastoma and implications for immunotherapeutic strategies.
Oncoimmunology
2019

TMOD-07. IN SITU MICROSCOPY OF DRUG AND IMMUNE CELL INTERACTIONS AGAINST BIOFABRICATED TUMOR MODELS
Neuro-Oncology
2019

TMIC-50. 3D QUANTIFICATION OF DYNAMIC CYTOKINE GRADIENTS PRODUCED BY PRIMARY TUMOR MODELS
Neuro-Oncology
2019

TMIC-49. ABROGATING CD70 EXPRESSION IN GBM RESULTS IN A REDUCED IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT
Neuro-Oncology
2019

TMIC-29. METABOLIC INTERACTIONS BETWEEN TREATMENT-RESISTANT SLOW-CYCLING CELLS AND THE IMMUNE SYSTEM IN HIGH-GRADE GLIOMA
Neuro-Oncology
2019

TMIC-08. IDENTIFICATION OF TUMOR SPECIFIC LYMPHOCYTES IN A MURINE GLIOMA MODEL
Neuro-Oncology
2019

Sarcosine promotes trafficking of dendritic cells to draining lymph nodes and improves efficacy of a vaccine strategy for the treatment of brain tumors via CX3CL1

2019

Sarcosine promotes trafficking of dendritic cells and improves efficacy of anti-tumor dendritic cell vaccines via CXC chemokine family signaling.
Journal for immunotherapy of cancer
2019

RNA-Modified T Cells Mediate Effective Delivery of Immunomodulatory Cytokines to Brain Tumors.
Molecular therapy : the journal of the American Society of Gene Therapy
2019

Quantitative characterization of 3D bioprinted structural elements under cell generated forces.
Nature communications
2019

Overcoming glioma immunoediting and MHC class I loss during adoptive cellular therapy
Cancer Research
2019

Modulation of temozolomide dose differentially affects T-cell response to immune checkpoint inhibition.
Neuro-oncology
2019

Massive clonal expansion of medulloblastoma-specific T cells during adoptive cellular therapy
Science Advances
2019

IMMUNOLOGIC TARGETING OF DIPG WITH H3K27M ENCODING RNA-NANOPARTICLES: IMMU-07.
Neuro-Oncology
2019

IMMU-47. RNA-NANOPARTICLE VACCINES ARE SAFE AND IMMUNOLOGICALLY ACTIVE IN CLIENT-OWNED CANINES WITH TERMINAL GLIOMAS
Neuro-Oncology
2019

IMMU-41. RNA-MODIFIED T CELLS AS PROFESSIONAL ANTIGEN PRESENTING CELLS
Neuro-Oncology
2019

IMMU-39. RNA LOADED LIPID-NANOPARTICLES FUNCTION AS CUSTOMIZABLE IMMUNOTHERAPEUTIC VEHICLES AGAINST MALIGNANT GLIOMAS
Neuro-Oncology
2019

IMMU-32. RNA-NANOPARTICLE VACCINES MEDIATE T CELL TRAFFICKING NECESSARY FOR BBB PASSAGE AND ANTI-GLIOMA IMMUNE RESPONSE
Neuro-Oncology
2019

IMMU-26. RADIATION AND TEMOZOLOMIDE UP-REGULATES CD70 EXPRESSION AND ENHANCES CAR T-CELL RECOGNITION IN GBM
Neuro-Oncology
2019

IMMU-25. MAGNETIC PARTICLE IMAGING FOR NON-INVASIVE TRACKING OF ADOPTIVE CELL TRANSFER IN CANCER IMMUNOTHERAPY
Neuro-Oncology
2019

IMMU-24. A COMPREHENSIVE IN SILICO APPROACH TO DISCOVERING TUMOR REJECTION ANTIGENS IN MALIGNANT BRAIN TUMORS
Neuro-Oncology
2019

IMMU-15. A UNIQUE SELF-STIMULATIVE PROPERTY OF CD70 CAR ADVANCES T CELL FUNCTION AND ANTI-TUMOR RESPONSE IN GLIOBLASTOMA
Neuro-Oncology
2019

IMMU-13. MECHANISMS OF IMMUNOLOGICAL ESCAPE DURING ADOPTIVE CELLULAR THERAPY IN HIGH GRADE GLIOMA
Neuro-Oncology
2019

IMMU-07. CELLULAR IMMUNOTHERAPY TO OVERCOME TEMOZOLOMIDE INDUCED T CELL EXHAUSTION IN GLIOBLASTOMA
Neuro-Oncology
2019

IMMU-05. DISRUPTION OF THE CCR2 CHEMOKINE RECEPTOR PATHWAY OVERCOMES THERAPEUTIC RESISTANCE TO PD-1 BLOCKADE IN MALIGNANT GLIOMA
Neuro-Oncology
2019

Highlights of the inaugural ten–the launch of Neuro-Oncology Advances
Neuro-Oncology Advances
2019

Emerging trends in immunotherapy for pediatric sarcomas.
Journal of hematology & oncology
2019

EXTH-15. INCREASING THE TRAFFICKING OF DENDRITIC CELLS VIA CXC CHEMOKINE SIGNALING PATHWAY LEADS TO IMPROVED ANTI-TUMOR EFFICACY OF DENDRITIC CELL VACCINES
Neuro-Oncology
2019

Dendritic Cell-Activating Magnetic Nanoparticles Enable Early Prediction of Antitumor Response with Magnetic Resonance Imaging.
ACS nano
2019

Concise Review: Modulating Cancer Immunity with Hematopoietic Stem and Progenitor Cells.
Stem cells (Dayton, Ohio)
2019

Chemotaxis of Spatially Patterned T cell Populations near 3D Printed Tumors

2019

CXCR1- or CXCR2-modified CAR T cells co-opt IL-8 for maximal antitumor efficacy in solid tumors.
Nature communications
2019

BSTM-03. INCREASING ANTI-TUMOR T CELL ACTIVATION, VELOCITY, AND MIGRATION TO BRAIN STEM GLIOMA USING HEMATOPOIETIC STEM AND PROGENITOR CELLS
Neuro-Oncology
2019

Adoptive cellular therapy overcomes tumor-induced dysregulation of myelopoiesis
Cancer Research
2019

ATIM-34. SINGLE-CELL RNA SEQUENCING REVEALS DYNAMIC IMMUNE RESPONSE CHANGES IN GLIOBLASTOMA PATIENT WITH DURABLE COMPLETE RESPONSE TO CMV PP65-LAMP RNA-PULSED DENDRITIC VACCINES
Neuro-Oncology
2019

ATIM-13. MULTIMODAL IMMUNOTHERAPY WITH IO-VAC® FOR PATIENTS WITH GBM: A SINGLE INSTITUTION EXPERIENCE
Neuro-Oncology
2019

3D in vitro system for immuno-oncology: Real-time imaging of drug delivery, tumoroids, and immune cell activity
Cancer Research
2019

mRNA-nanoparticles to enhance and track dendritic cell migration
Journal of Clinical Oncology
2018

Total tumor RNA pulsed dendritic cells plus adoptive transfer of ex-vivo enriched autologous T-lymphocytes in the treatment of children with primary brain tumors
Neuroimmunology and Neuroinflammation
2018

The IDH1 Mutation-Induced Oncometabolite, 2-Hydroxyglutarate, May Affect DNA Methylation and Expression of PD-L1 in Gliomas.
Frontiers in molecular neuroscience
2018

Temozolomide for immunomodulation in the treatment of glioblastoma.
Neuro-oncology
2018

TMIC-29. REPROGRAMMING BONE MARROW OF TUMOR-BEARING HOSTS FOR GLIOMA IMMUNOTHERAPY
Neuro-Oncology
2018

TMIC-29. REPROGRAMMING BONE MARROW OF TUMOR-BEARING HOSTS FOR GLIOMA IMMUNOTHERAPY
Neuro-Oncology
2018

TMIC-12. TUMOR-HOMING RNA-NANOPARTICLES REPROGRAM IMMUNE CELLS IN THE BRAIN TUMOR MICROENVIRONMENT
Neuro-Oncology
2018

THE IMPACT OF BRAIN TUMORS ON HEMATOPOIETIC STEM CELL-DERIVED T CELLS: IMMU-24
Neuro-Oncology
2018

STEM-09. CANCER STEM CELL IMMUNOEDITING
Neuro-Oncology
2018

Personalized Tumor RNA Loaded Lipid-Nanoparticles Prime the Systemic and Intratumoral Milieu for Response to Cancer Immunotherapy.
Nano letters
2018

PDTM-18. ACTIVATION OF TUMOR-REACTIVE T CELLS AGAINST BRAIN STEM GLIOMA USING HEMATOPOIETIC STEM CELLS
Neuro-Oncology
2018

PDCT-08. TRACKING THE T CELL REPERTOIRE AFTER ADOPTIVE CELL THERAPY IN PEDIATRIC PATIENTS WITH RECURRENT MEDULLOBLASTOMA
Neuro-Oncology
2018

MBRS-63. CCR2+ HEMATOPOIETIC STEM CELLS OVERCOME TREATMENT RESISTANCE TO PD-1 IN MEDULLOBLASTOMA
Neuro-Oncology
2018

MBRS-02. PERSONALIZED IMMUNOTHERAPY WITH TRANSLATABLE RNA NANOPARTICLES TARGETING MEDULLOBLASTOMA
Neuro-Oncology
2018

Lin-CCR2+ hematopoietic stem and progenitor cells overcome resistance to PD-1 blockade.
Nature communications
2018

Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma
The EMBO journal
2018

Infiltrative and drug-resistant slow-cycling cells support metabolic heterogeneity in glioblastoma.
The EMBO journal
2018

Immunotherapy for brain tumors
Current Treatment Options in Oncology
2018

Immunotherapy for Brain Tumors.
Current treatment options in oncology
2018

IMMU-67. PERSONALIZED TUMOR MRNA LOADED LIPID NANOPARTICLES PRIME THE SYSTEMIC AND INTRATUMORAL GBM MILIEU FOR RESPONSE TO IMMUNOTHERAPY
Neuro-Oncology
2018

IMMU-66. A NOVEL METABOLITE TO INCREASE EFFICACY OF CELLULAR IMMUNOTHERAPY IN THE TREATMENT OF GLIOBLASTOMA
Neuro-Oncology
2018

IMMU-64. A DECADE OF RESEARCH TARGETING IMMUNOSUPPRESSIVE IDO1 IN GLIOBLASTOMA: NEARING THE FINISH LINE OR JUST BEGINNING THE MARATHON?
Neuro-Oncology
2018

IMMU-56. CXCR1/2 MODIFIED CARs CO-OPT RADIATION-INDUCED IL-8 FOR ENHANCED CHEMOTAXIS OF THE CAR T CELLS AND MAXIMAL ANTI-TUMOR EFFICACY
Neuro-Oncology
2018

IMMU-45. DOSE MODULATION OF TEMOZOLOMIDE HAVE DISTINCT EFFECTS ON HOST RESPONSE TO PD-1 BLOCKADE
Neuro-Oncology
2018

IMMU-45. DOSE MODULATION OF TEMOZOLOMIDE HAVE DISTINCT EFFECTS ON HOST RESPONSE TO PD-1 BLOCKADE
Neuro-Oncology
2018

IMMU-45. DOSE MODULATION OF TEMOZOLOMIDE HAVE DISTINCT EFFECTS ON HOST RESPONSE TO PD-1 BLOCKADE
Neuro-Oncology
2018

IMMU-43. RNA-MODIFIED T CELLS AS A NON-INVASIVE AND EFFICACIOUS STRATEGY TO DELIVER THERAPEUTIC MACROMOLECULES LOCALLY TO INTRACRANIAL TUMORS
Neuro-Oncology
2018

IMMU-32. RETARGETING IMMUNOEDITED GLIOMA ESCAPE VARIANTS WITH ADOPTIVE CELLULAR THERAPY
Neuro-Oncology
2018

IMMU-27. Re-MATCH PROTOCOL: PHASE I STUDY OF AUTOLOGOUS TUMOR SPECIFIC LYMPHOCYTE TRANSFER (ALT) + DC VACCINE (DCV) DURING RECOVERY FROM MYELOABLATIVE CHEMOTHERAPY (MAC) AND AUTOLOGOUS STEM CELL RESCUE (HDC + ASCR) OR NON-MYELOABLATIVE CHEMOTHERAPY (NMAC) IN PATIENTS WITH RECURRENT CENTRAL PNETs (r-PNET)
Neuro-Oncology
2018

IMMU-20. HEMATOPOIETIC STEM CELLS POTENTIATE EFFICACY OF ADOPTIVE CELL THERAPY AGAINST BRAIN STEM GLIOMA
Neuro-Oncology
2018

IMMU-17. HEMATOPOIETIC STEM CELL-DERIVED DENDRITIC CELLS REPROGRAM THE BRAIN TUMOR MICROENVIRONMENT
Neuro-Oncology
2018

IMMU-15. HIGH-RESOLUTION ANALYSIS OF THE T-CELL RECEPTOR REPERTOIRE AFTER ADOPTIVE CELLULAR THERAPY IN PEDIATRIC PATIENTS WITH CENTRAL PNETs (Re-MATCH TRIAL)
Neuro-Oncology
2018

IMMU-09. Outcome of patients with recurrent diffuse intrinsic pontine glioma (DIPG) treated with pembrolizumab (anti-PD-1): a Pediatric Brain Tumor Consortium study (PBTC045)
Neuro-Oncology
2018

IMMU-04. RNA-ENGINEERED T CELLS AS A BIOLOGICAL CARRIER TO DELIVER MACROMOLECULES TO INTRACRANIAL TUMORS
Neuro-Oncology
2018

EXTH-36. BIFUNCTIONAL RNA NANOPARTICLES INDUCE ANTITUMOR IMMUNE RESPONSES AND ALLOW MRI-BASED DETECTION OF DENDRITIC CELL MIGRATION AS A BIOMARKER OF ANTITUMOR IMMUNE RESPONSE
Neuro-Oncology
2018

Dendritic Cells Enhance Polyfunctionality of Adoptively Transferred T Cells That Target Cytomegalovirus in Glioblastoma.
Cancer research
2018

DRES-13. VEGF BLOCKADE ENHANCES T REGULATORY CELL FUNCTION BY DYSREGULATING GLUTAMATE TRANSPORT IN GBM
Neuro-Oncology
2018

DDIS-06. AAV TOOLKIT ENABLING PRECISION COMBINATORIAL VIROTHERAPY FOR GLIOBLASTOMA
Neuro-Oncology
2018

Cross-talk between T Cells and Hematopoietic Stem Cells during Adoptive Cellular Therapy for Malignant Glioma.
Clinical cancer research : an official journal of the American Association for Cancer Research
2018

Cancer Vaccine Immunotherapy with RNA-Loaded Liposomes.
International journal of molecular sciences
2018

CD70, a novel target of CAR T-cell therapy for gliomas.
Neuro-oncology
2018

Analysis of immunobiologic markers in primary and recurrent glioblastoma
Journal of Neuro-Oncology
2018

2173 RNA-nanoparticles to enhance and track dendritic cell migration
Journal of Clinical and Translational Science
2018

Tumor associated CD70 expression is involved in promoting tumor migration and macrophage infiltration in GBM.
International journal of cancer
2017

Translational nanoparticle engineering for cancer vaccines.
Oncoimmunology
2017

The development of dendritic cell vaccine-based immunotherapies for glioblastoma.
Seminars in immunopathology
2017

The Effects of New or Worsened Postoperative Neurological Deficits on Survival of Patients With Glioblastoma
Journal of Neurosurgery
2017

The Clinical and Financial Impact of a Pediatric Surgical Neuro-Oncology Clinical Trial
Journal of Neuro-Oncology
2017

TMIC-26. IMMUNOMODULATION WITH TEMOZOLOMIDE TO IMPROVE EFFICACY OF IMMUNE CHECKPOINT INHIBITION FOR THE TREATMENT OF GLIOBLASTOMA
Neuro-Oncology
2017

TMIC-12. REPROGRAMMING THE BRAIN TUMOR MICROENVIRONMENT WITH HEMATOPOIETIC STEM AND PROGENITOR CELLS
Neuro-Oncology
2017

Systemic activation of antigen-presenting cells via RNA-loaded nanoparticles.
Oncoimmunology
2017

STEM-09. TREATMENT-RESISTANT SLOW-CYCLING CELLS SUPPORT METABOLIC HETEROGENEITY AND ADAPTABILITY IN GLIOBLASTOMA
Neuro-Oncology
2017

Regulatory T cell subsets in patients with medulloblastoma at diagnosis and during standard irradiation and chemotherapy (PBTC N-11)
Cancer Immunology Immunotherapy
2017

Preclinical and Clinical Demonstration of Immunogenicity by mRNA Vaccines against H10N8 and H7N9 Influenza Viruses
Human Vaccines and Immunotherapeutics
2017

PDCT-12. TRACKING T-CELL IMMUNE RECONSTITUTION AFTER ADOPTIVE CELLULAR THERAPY TARGETING RECURRENT MEDULLOBLASTOMA AND PNETS USING DEEP T-CELL RECEPTOR (TCR) REPERTOIRE SEQUENCING
Neuro-Oncology
2017

Overcoming resistance to immune checkpoint blockade with RNA-loaded nanoparticles
Journal of Clinical Oncology
2017

Manipulation of Innate and Adaptive Immunity through Cancer Vaccines.
Journal of immunology research
2017

METB-02. A SENSITIVE METABOLIC SIGNATURE TO PREDICT IMMUNE RESPONSE AFTER IMMUNOTHERAPY FOR BRAIN TUMORS
Neuro-Oncology
2017

Long-term Survival in Glioblastoma with Cytomegalovirus pp65-Targeted Vaccination.
Clinical cancer research : an official journal of the American Association for Cancer Research
2017

Immunotherapy for Pediatric Brain Tumors.
Brain sciences
2017

IMMU-68. REMODELING IMMUNITY AGAINST MEDULLOBLASTOMA VIA RNA-LOADED NANOPARTICLES
Neuro-Oncology
2017

IMMU-65. Lin-CCR2+ HEMATOPOIETIC STEM CELLS OVERCOME RESISTANCE TO PD-1 BLOCKADE
Neuro-Oncology
2017

IMMU-63. OVERCOMING GLIOBLASTOMA RESISTANCE TO IMMUNE CHECKPOINT BLOCKADE VIA RNA-LOADED NANOPARTICLES
Neuro-Oncology
2017

IMMU-57. STRATEGY TO ENHANCE DC MIGRATION FOR INCREASED EFFICACY OF DENDRITIC CELL VACCINE IMMUNOTHERAPY
Neuro-Oncology
2017

IMMU-31. IN VIVO CELLULAR TRACKING WITH 13C LABELING OF ADOPTIVELY TRANSFERRED T CELLS FOR THE TREATMENT OF BRAIN TUMORS
Neuro-Oncology
2017

IMMU-30. TCR Vb CLONAL EXPANSION PREDICTS RESPONSE TO ADOPTIVE IMMUNOTHERAPY AGAINST MEDULLOBLASTOMA
Neuro-Oncology
2017

IMMU-25. ENHANCED T CELLS TUMOR RECOGNITION USING DENDRITIC CELLS PULSED WITH CHIMERIC RNAs ENCODING FULL-LENGTH LAMP-1 FUSION CONSTRUCTS
Neuro-Oncology
2017

IMMU-25. ENHANCED T CELLS TUMOR RECOGNITION USING DENDRITIC CELLS PULSED WITH CHIMERIC RNAs ENCODING FULL-LENGTH LAMP-1 FUSION CONSTRUCTS
Neuro-Oncology
2017

IMMU-22. ADOPTIVE CELL THERAPY AGAINST DIPG USING DEVELOPMENTALLY REGULATED ANTIGENS
Neuro-Oncology
2017

IMMU-14. REMODELING IMMUNITY AGAINST MEDULLOBLASTOMA VIA RNA LOADED NANOPARTICLES
Neuro-Oncology
2017

IMMU-14. REMODELING IMMUNITY AGAINST MEDULLOBLASTOMA VIA RNA LOADED NANOPARTICLES
Neuro-Oncology
2017

IMMU-11. AN ANALYSIS OF IMMUNOPHENOTYPE, INCLUDING PD-L1 AND PD1 EXPRESSION, IN PEDIATRIC CNS MALIGNANCIES: A PEDIATRIC BRAIN TUMOR CONSORTIUM STUDY
Neuro-Oncology
2017

DIPG-23. PHASE I STUDY OF ADOPTIVE CELLULAR THERAPY (X-ALT) PLUS TOTAL TUMOR RNA-DENDRITIC CELL VACCINE (TTRNA-DC) + HEMATOPOIETIC STEM CELLS (HSC) DURING RECOVERY FROM IRRADIATION(RT) WITH (GROUP A) OR WITHOUT (GROUP B) DOSE-INTENSIFIED TEMOZOLOMIDE (DI-TMZ) IN PATIENT (PTS) WITH NEWLY DIAGNOSED DIFFUSE BRAIN STEM GLIOMAS (DIPG) (BRAVO TRIAL)
Neuro-Oncology
2017

CD70 as a critical mediator of tumor progression and immunosuppression in gliomas
Journal of Clinical Oncology
2017

CD4+ and Perivascular Foxp3+ T Cells in Glioma Correlate with Angiogenesis and Tumor Progression.
Frontiers in immunology
2017

Adoptive Immunotherapy Against Brain Tumors
Translational Immunotherapy of Brain Tumors
2017

A phase I trial of pomalidomide for children with recurrent, progressive/refractory central nervous system (CNS) tumors: A Pediatric Brain Tumor Consortium (PBTC) study.
Journal of Clinical Oncology
2017

2422: Magnetic nanoparticles facilitate tracking of dendritic cells for treatment of malignant brain tumors
Journal of Clinical and Translational Science
2017

Vaccine-related allergic reaction: case report

2016

Tetanus-Diphtheria Recall Responses and Chemokine CCL3 Delivery Enhance Migration and Efficacy of Dendritic Cell Vaccines
Journal Of Neurosurgery
2016

TMIC-14. TUMOR EVOLUTION OF GLIOMA INTRINSIC GENE EXPRESSION SUBTYPE ASSOCIATES WITH IMMUNOLOGICAL CHANGES IN THE MICROENVIRONMENT
Neuro-Oncology
2016

Reviewer Lists for Neuro-Oncology
Neuro-Oncology
2016

QUANTITATIVE TRACKING OF T-CELL CLONES AFTER ADOPTIVE CELLULAR THERAPY TARGETING RECURRENT MEDULLOBLASTOMA USING MASSIVELY PARALLEL RNA SEQUENCING TECHNOLOGY
Neuro-Oncology
2016

Prioritization schema for immunotherapy clinical trials in glioblastoma.
Oncoimmunology
2016

PDCT-15. Re-MATCH: A PHASE 2 MULTI-INSTITUTIONAL CLINICAL TRIAL OF ADOPTIVE CELLULAR THERAPY FOLLOWING MYELOABLATIVE OR NON-MYELOABLATIVE CHEMOTHERAPY IN CHILDREN AND YOUNG ADULTS WITH RECURRENT MEDULLOBLASTOMA AND PNETs
Neuro-Oncology
2016

Migration of dendritic cells to the lymph nodes and its enhancement to drive anti-tumor responses
Critical Reviews In Oncology/Hematology
2016

MicroRNAs provide a novel pathway toward combinatorial immune checkpoint blockade.
Neuro-oncology
2016

MB-94 IMMUNOLOGIC PROFILE OF PATIENTS WITH NEWLY-DIAGNOSED MEDULLOBLASTOMA AT INITIAL DIAGNOSIS AND DURING STANDARD RADIATION AND CHEMOTHERAPY (PBTC-N11)
Neuro-Oncology
2016

Know your neighbors: Different tumor microenvironments have implications in immunotherapeutic targeting strategies across MB subgroups.
Oncoimmunology
2016

IMST-55. LYMPH NODE AND URINE METABOLOMICS: A NON-INVASIVE STRATEGY TO PREDICT EFFICACY OF DENDRITIC CELL VACCINE IMMUNOTHERAPY
Neuro-Oncology
2016

IMST-47. IDENTIFICATION AND EXPANSION OF GLIOMA-SPECIFIC T CELLS USING TCR Vβ EXPRESSION
Neuro-Oncology
2016

IMST-33. ENHANCED T CELL ACTIVATION USING DENDRITIC CELLS PULSED WITH CHIMERIC RNAs ENCODING FULL-LENGTH LAMP-1 FUSION CONSTRUCTS
Neuro-Oncology
2016

IMST-27. CD70–A CRITICAL MEDIATOR OF TUMOR PROGRESSION AND IMMUNOSUPPRESSION IN GLIOMAS
Neuro-Oncology
2016

IMST-16. TRANSLATABLE RNA NANOPARTICLES SUPPLANT DENDRITIC CELL VACCINES IN CELLULAR IMMUNOTHERAPY
Neuro-Oncology
2016

Gene-modified dendritic cell vaccines for cancer.
Cytotherapy
2016

Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis.
Oncotarget
2016

Differential Immune Microenvironments and Response to Immune Checkpoint Blockade among Molecular Subtypes of Murine Medulloblastoma.
Clinical cancer research : an official journal of the American Association for Cancer Research
2016

COMBINATION OF VEGF-A AND PD-1 BLOCKADE MAY ENHANCE ANTITUMOR EFFICACY IN GBM
Neuro-Oncology
2016

CMV-targeted Dendritic Cell Vaccines Increase Survival for Randomized Patients with Glioblastoma in Successive Trials
Journal of Neurosurgery
2016

Vaccination strategies for neuro-oncology.
Neuro-oncology
2015

Tetanus toxoid conditioning enhances migration and efficacy of dendritic cell vaccines in patients with glioblastoma

2015

Tetanus toxoid and CCL3 improve dendritic cell vaccines in mice and glioblastoma patients
Nature
2015

Severe adverse immunologic reaction in a patient with glioblastoma receiving autologous dendritic cell vaccines combined with GM-CSF and dose-intensified temozolomide.
Cancer immunology research
2015

Rna Nanoparticle Vaccines Facilitate and Sustain Adoptive Cellular Therapy Targeting Pediatric Intracranial Malignancies
Pediatric Blood & Cancer
2015

RNA NANOPARTICLE VACCINES FACILITATE AND SUSTAIN ADOPTIVE CELLULAR THERAPY TARGETING PEDIATRIC INTRACRANIAL MALIGNANCIES: YOUNG INVESTIGATOR AWARD WINNER# 4012
Pediatric Blood & Cancer
2015

Novel role of hematopoietic stem cells in immunologic rejection of malignant gliomas.
Oncoimmunology
2015

METB-02USING MAGNETIC RESONANCE SPECTROSCOPY TO TRACK DENDRITIC CELLS FOR VACCINE IMMUNOTHERAPY
Neuro-Oncology
2015

Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma
Cancer Immunology Immunotherapy
2015

Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma.
Cancer immunology, immunotherapy : CII
2015

IMPS-42 CD70—A KEY DRIVER OF CHEMOKINE-MEDIATED IMMUNE SUPPRESSION AND INDICATOR OF NEGATIVE PROGNOSIS FOR GLIOBLASTOMA
Neuro-Oncology
2015

IMPS-36RNA NANOPARTICLE VACCINES RE-PROGRAM HOST-IMMUNITY AGAINST GLIOBLASTOMA INDUCING THERAPEUTIC ANTI-TUMOR ACTIVITY
Neuro-Oncology
2015

IMPS-25DIFFERENTIAL TUMOR MICROENVIRONMENTS AND RESPONSE TO IMMUNE CHECKPOINT BLOCKADE IN MOLECULAR SUBTYPES OF MURINE MEDULLOBLASTOMA
Neuro-Oncology
2015

IM-15ANTI-TUMOR EFFICACY OF ADOPTIVE CELLULAR THERAPY IS SIGNIFICANTLY INCREASED BY HEMATOPOIETIC STEM CELLS
Neuro-Oncology
2015

IM-14IMMUNOLOGIC TARGETING OF MEDULLOBLASTOMA SUBTYPES USING DEVELOPMENTALLY REGULATED ANTIGENS
Neuro-Oncology
2015

IM-13MOLECULAR ENGINEERING OF AMPLIFIED TUMOR RNA-PULSED DENDRITIC CELLS IN ADOPTIVE CELLULAR THERAPY TARGETING MEDULLOBLASTOMA AND GLIOBLASTOMA
Neuro-Oncology
2015

IM-12 RNA NANOPARTICLE VACCINES RE-PROGRAM HOST IMMUNITY IN FAVOR OF ENHANCED EFFECTOR RESPONSES AGAINST INTRACRANIAL MALIGNANCIES
Neuro-Oncology
2015

IM-12 RNA NANOPARTICLE VACCINES RE-PROGRAM HOST IMMUNITY IN FAVOR OF ENHANCED EFFECTOR RESPONSES AGAINST INTRACRANIAL MALIGNANCIES
Neuro-Oncology
2015

IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas
Neuro-Oncology
2015

Ex vivo generation of dendritic cells from cryopreserved, post-induction chemotherapy, mobilized leukapheresis from pediatric patients with medulloblastoma.
Journal of neuro-oncology
2015

Bridging infectious disease vaccines with cancer immunotherapy: a role for targeted RNA based immunotherapeutics.
Journal for immunotherapy of cancer
2015

Recognition and killing of autologous, primary glioblastoma tumor cells by human cytomegalovirus pp65-specific cytotoxic T cells
Clinical Cancer Research
2014

ROBUST INDUCTION OF TYPE-1 CD8+ T-CELL RESPONSES IN WHO GRADE II LOW-GRADE GLIOMA PATIENTS RECEIVING PEPTIDE-BASED VACCINES IN COMBINATION WITH POLY-ICLC
Neuro-Oncology
2014

Memory Responses Govern Dendritic Cell Migration to Vaccine-Site Draining Lymph Nodes Resulting in Enhanced Anti-Tumor Efficacy
Journal of Surgical Research
2014

Immunological targeting of cytomegalovirus for glioblastoma therapy.
Oncoimmunology
2014

IT-35 cGMP MANUFACTURING OF EX VIVO EXPANDED TUMOR-SPECIFIC T CELLS AND AMPLIFIED TUMOR RNA-PULSED DC VACCINES TARGETING GLIOBLASTOMA AND MEDULLOBLASTOMA
Neuro-Oncology
2014

IT-31HARNESSING THE IMMUNOLOGIC CAPACITY OF THE LIVER AGAINST GLIOBLASTOMA MULTIFORME
Neuro-Oncology
2014

IT-25DEVELOPMENTALLY REGULATED ANTIGENS FOR IMMUNOLOGIC TARGETING OF MEDULLOBLASTOMA SUBTYPES
Neuro-Oncology
2014

IT-10SYNERGISTIC CELLULAR INTERACTIONS IN ADOPTIVE IMMUNOTHERAPY LEADS TO IMMUNOLOGIC REJECTION OF MALIGNANT GLIOMA
Neuro-Oncology
2014

IT-06PERSONALIZED IMMUNOTHERAPY FOR THE TREATMENT OF GLIOBLASTOMA
Neuro-Oncology
2014

GE-11THE FLORIDA CENTER FOR BRAIN TUMOR RESEARCH (FCBTR): BUILDING INFRASTRUCTURE TO FIND A CURE
Neuro-Oncology
2014

Differential role for host translation factors in host and viral protein synthesis during human cytomegalovirus infection
Journal Of Virology
2014

Targeting cytomegalovirus (CMV) antigens for GBM immunotherapy

2013

Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma.
Proceedings of the National Academy of Sciences of the United States of America
2013

Special issue on epilepsy.
Experimental neurology
2013

Myeloablative temozolomide enhances CD8⁺ T-cell responses to vaccine and is required for efficacy against brain tumors in mice.
PloS one
2013

Melanoma immunotherapy using mature DCs expressing the constitutive proteasome.
The Journal of clinical investigation
2013

IT-017. TARGETING IDH1 MUTATIONS USING PEPTIDE VACCINES IN BRAIN TUMORS
Neuro-Oncology
2013

IT-004. A BISPECIFIC ANTIBODY REDIRECTS REGULATORY T CELLS TO KILL TUMOR CELLS THROUGH GRANZYME-DEPENDENT CYTOTOXICITY
Neuro-Oncology
2013

IT-004. A BISPECIFIC ANTIBODY REDIRECTS REGULATORY T CELLS TO KILL TUMOR CELLS THROUGH GRANZYME-DEPENDENT CYTOTOXICITY
Neuro-Oncology
2013

IMMUNOTHERAPY/BIOLOGICAL THERAPIES
Neuro-Oncology
2013

Human regulatory T cells kill tumor cells through granzyme-dependent cytotoxicity upon retargeting with a bispecific antibody.
Cancer immunology research
2013

ENGINEERING RNA NANOPARTICLE VACCINES TO TARGET MALIGNANT PEDIATRIC BRAIN TUMORS: PLATFORM SESSION 413-TRAVEL STIPEND AWARD WINNER
Pediatric Blood & Cancer
2013

BLyS levels correlate with vaccine-induced antibody titers in patients with glioblastoma lymphodepleted by therapeutic temozolomide.
Cancer immunology, immunotherapy : CII
2013

Antibody, T-cell and dendritic cell immunotherapy for malignant brain tumors.
Future oncology (London, England)
2013

An update on vaccine therapy and other immunotherapeutic approaches for glioblastoma.
Expert review of vaccines
2013

An EGFRvIII-targeted bispecific T-cell engager overcomes limitations of the standard of care for glioblastoma.
Expert review of clinical pharmacology
2013

A cytokine cocktail directly modulates the phenotype of DC-enriched anti-tumor T cells to convey potent anti-tumor activities in a murine model.
Cancer immunology, immunotherapy : CII
2013

0175. A PHASE I/II STUDY OF ADOPTIVE T- CELL THERAPY (ALT) AND DC VACCINATION (DCV) DURING RECOVERY FROM MYELOABLATIVE CHEMOTHERAPY AND HEMATOPOIETIC STEM CELL TRANSPLANTATION (HDC + ASCR) OR NON-MYELOABLATIVE CONDITIONING (NMA) IN PATIENTS (PTS) WITH RECURRENT CENTRAL PNETS (RE-MATCH PROTOCOL)
Neuro-Oncology
2013

0157. NOVEL ROLE FOR ENHANCING IMMUNOTHERAPY AGAINST PEDIATRIC BRAIN TUMORS USING HEMATOPOIETIC STEM CELLS
Neuro-Oncology
2013

0157. NOVEL ROLE FOR ENHANCING IMMUNOTHERAPY AGAINST PEDIATRIC BRAIN TUMORS USING HEMATOPOIETIC STEM CELLS
Neuro-Oncology
2013

0134. RNA NANOPARTICLE VACCINES RE-DIRECT HOST-IMMUNITY AGAINST INTRACRANIAL MALIGNANCIES
Neuro-Oncology
2013

0003. PRELIMINARY STUDY Rg3-NANOPARTICLES TREAT GLIOBLASTOMA CELLS
Neuro-Oncology
2013

TM-14. DEVELOPMENT OF IMMUNOCOMPETENT SYNGENEIC MODELS OF MEDULLOBLASTOMA FOR EVALUATION OF IMMUNOTHERAPY
Neuro-Oncology
2012

RNA NANOPARTICLE VACCINES TARGETING MEDULLOBLASTOMA:(POSTER 698)
Pediatric Blood & Cancer
2012

Monoclonal antibody therapy for malignant glioma.
Advances in experimental medicine and biology
2012

Immunotherapy of brain tumors.
Handbook of clinical neurology
2012

IT-27. ADOPTIVE CELLULAR THERAPY TARGETING RECURRENT MEDULLOBLASTOMA AND PRIMITIVE NEUROECTODERMAL TUMORS AFTER MYELOABLATIVE AND NON-MYELOABLATIVE CONDITIONING
Neuro-Oncology
2012

IT-26. FEASIBILITY OF AMPLIFIED CD133 (+) BRAIN TUMOR STEM CELL RNA-PULSED DENDRITIC CELLS FOR THE TREATMENT OF PATIENTS WITH RECURRENT GLIOBLASTOMA
Neuro-Oncology
2012

IT-20. DENDRITIC CELL VACCINES TARGETING HUMAN CYTOMEGALOVIRUS IN GLIOBLASTOMA REVEAL LYMPH NODE HOMING AS A MAJOR AXIS FOR CLINICAL INTERVENTION
Neuro-Oncology
2012

IT-20. DENDRITIC CELL VACCINES TARGETING HUMAN CYTOMEGALOVIRUS IN GLIOBLASTOMA REVEAL LYMPH NODE HOMING AS A MAJOR AXIS FOR CLINICAL INTERVENTION
Neuro-Oncology
2012

IT-09. EX VIVO GENERATION OF CENTRAL MEMORY-LIKE ANTI-TUMOR T CELLS TO TREAT MALIGNANT BRAIN TUMORS
Neuro-Oncology
2012

IR-15. ENHANCEMENT OF DENDRITIC CELL MIGRATION TO VACCINE-SITE DRAINING LYMPH NODES AS A MEANS TO GENERATE POTENT ANTI-TUMOR IMMUNE RESPONSES
Neuro-Oncology
2012

IR-13. MYELOABLATIVE TEMOZOLOMIDE INCREASES ANTIGEN-SPECIFIC CD8+ T-CELL VACCINE RESPONSES AND IS REQUIRED FOR EFFICACIOUS IMMUNOTHERAPY AGAINST INTRACEREBRAL TUMORS
Neuro-Oncology
2012

IR-09. DEVELOPING RNA NANOPARTICLE VACCINES TARGETING PEDIATRIC AND ADULT BRAIN TUMORS
Neuro-Oncology
2012

IR-08. ASSESSMENT OF INTRATUMORAL TREGS AND CLINICAL OUTCOMES IN PRIMARY AND RECURRENT GLIOBLASTOMA
Neuro-Oncology
2012

ET-49. ROLE OF HEMATOPOIETIC STEM CELLS IN ENHANCING THE ANTI-TUMOR EFFICACY OF ADOPTIVE CELLULAR THERAPY
Neuro-Oncology
2012

ET-35. TARGETING CYTOMEGALOVIRUS ANTIGENS FOR GLIOBLASTOMA IMMUNOTHERAPY
Neuro-Oncology
2012

Chasing cancer with chimeric antigen receptor therapy.
Immunotherapy
2012

A pilot study of IL-2Rα blockade during lymphopenia depletes regulatory T-cells and correlates with enhanced immunity in patients with glioblastoma.
PloS one
2012

Temozolamide and Radiation Therapy Does Not Cause EGFRvIII Loss
Journal Of Neurosurgery
2011

Reply to MS Lesniak
Journal of Clinical Oncology
2011

Monoclonal antibody blockade of IL-2 receptor α during lymphopenia selectively depletes regulatory T cells in mice and humans.
Blood
2011

Is cytomegalovirus a therapeutic target in glioblastoma?
Clinical cancer research : an official journal of the American Association for Cancer Research
2011

Immunotherapy for glioblastoma: The Devil Is in the Details Reply
Journal of Clinical Oncology
2011

IMMUNOLOGIC PROFILE OF PATIENTS WITH NEWLY DIAGNOSED MEDULLOBLASTOMA
Neuro-Oncology
2011

IMMUNOLOGIC PROFILE OF PATIENTS WITH NEWLY DIAGNOSED MEDULLOBLASTOMA
Neuro-Oncology
2011

IM-23. CYTOMEGALOVIRUS-SPECIFIC IMMUNE DEFICITS IN PATIENTS WITH GBM
Neuro-Oncology
2011

IM-22. DENDRITIC CELL VACCINES TARGETING CYTOMEGALOVIRUS IN GLIOBLASTOMA
Neuro-Oncology
2011

Greater chemotherapy-induced lymphopenia enhances tumor-specific immune responses that eliminate EGFRvIII-expressing tumor cells in patients with glioblastoma.
Neuro-oncology
2011

Direct2Experts: a Pilot National Network To Demonstrate Interoperability Among Research-Networking Platforms
Journal of the American Medical Informatics Association : JAMIA
2011

Direct2Experts Collaboration Direct2Experts: a pilot national network to demonstrate interoperability among research-networking platforms
Journal of the American Medical Informatics Association
2011

Cellular Immunotherapy for Malignant Brain Tumors

2011

ADOPTIVE CELLULAR THERAPY DURING RECOVERY FROM TREATMENT-INDUCED LYMPHOPENIA IN PEDIATRIC PATIENTS WITH RECURRENT MEDULLOBLASTOMA AND PNETs
Neuro-Oncology
2011

A promising cancer vaccine
Future Oncology
2011

Survivin as an immunotherapeutic target for adult and pediatric malignant brain tumors.
Cancer immunology, immunotherapy : CII
2010

Interleukin-2 receptor α (IL-2R α/CD25)-specific antibodies eliminate regulatory T-cells (TRegs) and enhance tumor-specific immune responses
Cancer Research
2010

Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
2010

Toward effective immunotherapy for the treatment of malignant brain tumors.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
2009

Proteomic and immunologic analyses of brain tumor exosomes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
2009

INDUCTION OF IMMUNOLOGIC AND CLINICAL RESPONSES WITH EGFRVIII-TARGETED VACCINE (CDX-110) WITH CYCLES OF TEMOZOLOMIDE IN PATIENTS WITH NEWLY DIAGNOSED EGFRVIII-POSITIVE GBM
Neuro-Oncology
2009

Epidermal growth factor receptor variant III (EGFRvIII) vaccine (CDX-110) in GBM
Journal of Clinical Oncology
2009

Effect of daclizumab on TReg counts and EGFRvIII-specific immune responses in GBM
Journal of Clinical Oncology
2009

EGFRvIII-targeted vaccination therapy of malignant glioma.
Brain pathology (Zurich, Switzerland)
2009

CELLULAR IMMUNOTHERAPY TRIALS TARGETING HUMAN CYTOMEGALOVIRUS ANTIGENS IN GLIOBLASTOMA
Neuro-Oncology
2009

CELLULAR IMMUNOTHERAPY TRIALS TARGETING HUMAN CYTOMEGALOVIRUS ANTIGENS IN GLIOBLASTOMA
Neuro-Oncology
2009

An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme.
Molecular cancer therapeutics
2009

236. RNA Transfected Dendritic Cell Vaccines Targeting Human Cytomegalovirus Antigens in Patients with Glioblastoma
Molecular Therapy
2009

Tumor-specific immunotherapy targeting the EGFRvIII mutation in patients with malignant glioma.
Seminars in immunology
2008

THE POSITIVE INFLUENCE OF TEMOZOLOMIDE ON THE HUMORAL AND CELL-MEDIATED (DTH) RESPONSES TO EGFRVIII-TARGETED VACCINE (CDX-110) IN PATIENTS WITH GBM
Neuro-Oncology
2008

Sensitive detection of human cytomegalovirus in tumors and peripheral blood of patients diagnosed with glioblastoma.
Neuro-oncology
2008

Selective modification of antigen-specific T cells by RNA electroporation.
Human gene therapy
2008

Immunotherapy of malignant brain tumors.
Immunological reviews
2008

Immunological responses in a patient with glioblastoma multiforme treated with sequential courses of temozolomide and immunotherapy: case study.
Neuro-oncology
2008

Humoral and cell mediated responses to the EGFRvIII-targeted vaccine (CDX-110) are enhanced with continuous temozolomide in patients with GBM

2008

Efficacy of a phase II vaccine targeting Cytomegalovirus antigens in newly diagnosed GBM
Journal of Clinical Oncology
2008

Efficacy and immunologic effects of RNA-pulsed dendritic cell vaccines targeting human cytomegalovirus antigens in patients with glioblastoma

2008

Effect of EGFRvIII-targeted vaccine (CDX-110) on immune response and TTP when given with simultaneous standard and continuous temozolomide in patients with GBM
Journal of Clinical Oncology
2008

EGFRvIII-targeted immunotoxin induces antitumor immunity that is inhibited in the absence of CD4+ and CD8+ T cells.
Cancer immunology, immunotherapy : CII
2008

Detection of humoral response in patients with glioblastoma receiving EGFRvIII-KLH vaccines.
Journal of immunological methods
2008

A phase I/II clinical trial evaluating RNA-loaded dendritic cells targeting human cytomegalovirus in patients with newly-diagnosed GBM
Journal of Neurosurgery
2008

Temozolomide therapy induces an increase in regulatory T-cells without abbrogating a specific tumor
Neuro-Oncology
2007

Temozolomide as a vaccine adjuvant in GBM
Journal of Clinical Oncology
2007

Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function.
Clinical cancer research : an official journal of the American Association for Cancer Research
2007

RNA-loaded dendritic cells targeting cytomegalovirus in patients with malignant glioma
Neuro-Oncology
2007

Induction of enhanced immunologic responses during hematopoeitic recovery from temozolomide-induced lymphopenia
Neuro-Oncology
2007

Genetic analysis of intracranial tumors in a murine model of glioma demonstrate a shift in gene expression in response to host immunity.
Journal of neuroimmunology
2007

Systemic anti-CD25 monoclonal antibody administration safely enhances immunity in murine glioma without eliminating regulatory T cells.
Clinical cancer research : an official journal of the American Association for Cancer Research
2006

Radiotherapy with regulatory T-cell depletion is synergistic for treatment of experimental model of malignant glioma

2006

Profiling of CD4+, CD8+, and CD4+CD25+CD45RO+FoxP3+ T cells in patients with malignant glioma reveals differential expression of the immunologic transcriptome compared with T cells from healthy volunteers.
Clinical cancer research : an official journal of the American Association for Cancer Research
2006

Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
Cancer research
2006

Immunotherapy for Malignant Glioma

2005

Expression profiling of CD4+ and CD8+ T cells in malignant glioma
Clinical Cancer Research
2005

Development and characterization of a novel murine brain tumor model of cytomegalovirus-associateid malignant astrocytoma
Neuro-Oncology
2004

Detection and immunologic recognition of cytomegalovirus antigens expressed within malignant gliomas
Neuro-Oncology
2004

Cytomegalovirus-specific antigens are effective targets for adoptive immunotherapy in malignant gliomas
Neuro-Oncology
2004

The history, evolution, and clinical use of dendritic cell-based immunization strategies in the therapy of brain tumors.
Journal of neuro-oncology
2003

Adoptive immunotherapy for malignant glioma.
Cancer journal (Sudbury, Mass.)
2003

Dendritic Cell Therapy

2001

RNA-transfected dendritic cells in cancer immunotherapy.
The Journal of clinical investigation
2000

Dendritic cells capture tumor derived antigens in vivo and mediate class I-restricted" cross-priming" of tumor specific cytotoxic T-cells
Journal of Investigative Dermatology
2000

Calreticulin displays in vivo peptide-binding activity and can elicit CTL responses against bound peptides.
Journal of immunology (Baltimore, Md. : 1950)
1999

Direct demonstration of" cross-priming": In situ transfer of tumor antigen to dendritic cells
Journal Of Leukocyte Biology
1998

Dendritic cell/macrophage precursors capture exogenous antigen for MHC class I presentation by dendritic cells.
European journal of immunology
1998

I-131 anti-CD45 antibody as a part of a conditioning regimen prior to bone marrow transplantation acute leukemia
Journal of Nuclear Medicine
1996

Molecular biology of Cryptococcus neoformans and therapy of cryptococcosis.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology
1994

Selection of antihypertensive therapy.
American heart journal
1990

Dosages for labetalol.
Chest
1989