Intrinsic factor is a protein that helps your intestines absorb vitamin B12. It is made by cells in the stomach lining.
Intrinsic factor is a protein that helps your body absorb vitamin B12. Vitamin B12 is needed for red blood cells to form and grow.
Some people do not make enough intrinsic factor or have a condition that destroys it. If your body does not make enough intrinsic factor, you can develop a type of vitamin B12 deficiency called pernicious anemia.
Surgical removal of the stomach and certain other health conditions can also cause you to stop making intrinsic factor.
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Antony AC. Megaloblastic anemias. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 164.