Pancreatic cancer: Research Studies

6 Related Result(s)

  1. Phase 1a/1b Dose Escalation and Expansion Study of SBP-101 in Combination with Nab-Paclitaxel and Gemcitabine in Subjects with Previously Untreated Metastatic Pancreatic Ductal Adenocarcinoma

    The primary objective of the Phase 1a dose-escalation study is to determine the RD and DLTs of SBP-101 when administered in combination with standard dose...

  2. A Phase II Trial of TAS-102 (Lonsurf) in Patients With Metastatic or Locally Advanced Unresectable Pancreatic Adenocarcinoma After Progression Through First Line Chemotherapy

    The primary objective is to evaluate the activity of TAS-102 in previously treated metastatic and locally...

  3. Open Label Phase 2 Study of Tisotumab Vedotin for Locally Advanced or Metastatic Disease in Solid Tumors

    Evaluate antitumor activity of tisotumab vedotin as measured by investigator-determined confirmed objective response rate using Response Evaluation Criteria...

  4. A Phase II, Open-label Evaluating the Safety and Activity of naI-IRI in Combination with 5-FU and Oxaliplatin in Preoperative Treatment of Pancreatic Adenocarcinoma

    This is a phase II, single arm, non-randomized, open label study of liposomal irinotecan with FOLFOX in the neoadjuvant setting in patients with borderline...

  5. Targeted Therapy Directed by Genetic Testing in Advanced Refractory Solid Tumors or Lymphomas

    This phase II MATCH trial studies how well treatment that is directed by genetic testing works in patients with solid tumors or lymphomas that have...

  6. Phase II Trial of Niraparib in BAP1 and other DDR Deficient Neoplasms (UF-STO-ETI-001)

    The purpose of this study is to investigate the use of niraparib in patients with tumors known to have mutations in BAP1 and other select DNA damage...