A Randomized Phase III Study of Brentuximab Vedotin (SGN-35, IND #117117) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents
The purpose of this study is to assess the event free survival (EFS) of a novel regimen incorporating brentuximab vedotin (Bv; AdcetrisTM) in the chemotherapy backbone of doxorubicin (Adriamycin), vincristine, etoposide, prednisone and cyclophosphamide (Bv-AVEPC) in newly diagnosed high-risk cHL compared to those treated with ABVE-PC.
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Keywordschemotherapy, High-Risk Classical Hodgkin Lymphoma, Newly Diagnosed, Children, Adolescents
Principal InvestigatorWilliam B Slayton, M.D.
Sponsoring GroupDepartment of Pediatrics
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