Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA


Currently many patients with a diagnosis of Giant Cell Arteritis (GCA) are on steroid therapy to help manage their disease. This study aims to explore the ability of biologic drug Kevzara to reduce the overall steroid exposure and help patients attain remission. Patients who have GCA and are interested in being a part of this study are invited to contact the study team to see if they qualify.


  • Diagnosis of giant cell arteritis (GCA) according to European League Against Rheumatism/American College of Rheumatology classification criteria
  • New onset active disease or refractory active disease
  • At least one of the symptoms of GCA within 6 weeks of baseline
  • Either erythrocyte sedimentation rate ≥30 mm/hour or C-reactive protein ≥10 mg/L within 6 weeks of baseline
  • Receiving or able to receive prednisone 20-60 mg/day for the treatment of active GCA

Additional inclusion and exclusion criteria apply. 


18 to 65
65 and over




giant cell arteritis, GCA

Principal Investigator

Michael R Bubb, M.D.



Contact Information


800-633-1610 ext 1 then #

Be an Informed Participant

Before deciding to participate in a research study, take time to learn about clinical research, how it's conducted and your rights as a research participant. Following are some helpful resources from independent sources. Always remember that a clinical research study is research, not treatment.

Know Who to Contact

  • Eligibility: For questions about a specific study and who is eligible to participate, call or email the contact person listed for that study.
  • Your Rights: For questions about your rights as a research participant, contact the UF Institutional Review Boards at 352-273-9600.
  • Feedback: For general questions or feedback about study listings, email the UF Clinical and Translational Science Institute at CTSI-Studies-L@lists.ufl.edu.

Other Resources

  • HealthStreet: Health-focused services, classes and events, and opportunities to participate in research.
  • ResearchMatch.org: Join a national registry of volunteers willing to be contacted about research studies.

For Research Teams