Evaluation of Efficacy and Safety of Sarilumab in Patients With GCA

Purpose

Currently many patients with a diagnosis of Giant Cell Arteritis (GCA) are on steroid therapy to help manage their disease. This study aims to explore the ability of biologic drug Kevzara to reduce the overall steroid exposure and help patients attain remission. Patients who have GCA and are interested in being a part of this study are invited to contact the study team to see if they qualify.

Eligibility

  • Diagnosis of giant cell arteritis (GCA) according to European League Against Rheumatism/American College of Rheumatology classification criteria
  • New onset active disease or refractory active disease
  • At least one of the symptoms of GCA within 6 weeks of baseline
  • Either erythrocyte sedimentation rate ≥30 mm/hour or C-reactive protein ≥10 mg/L within 6 weeks of baseline
  • Receiving or able to receive prednisone 20-60 mg/day for the treatment of active GCA

Additional inclusion and exclusion criteria apply. 

Age

18 to 65
65 and over

Gender

N/A

Keywords

giant cell arteritis, GCA

Principal Investigator

Michael R Bubb, M.D.

Department

Rheumatology

Contact Information

Contact-US@sanofi.com

800-633-1610 ext 1 then #


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