Study of Cardiac MRI in Patients With Left-Sided Breast Cancer Receiving Radiation Therapy
This is a pilot study to determine if there are changes in heart function following completion of radiation therapy for breast cancer as measured by cardiac magnetic resonance imaging (cardiac MRI) scans.
Additional purposes of this study are to assess cardiac side effects from radiation treatment, evaluate cardiac MRI changes by radiation technique, and compare the quality of life questionnaires.
As part of this study, participants will have a cardiac MRI at baseline and a follow-up cardiac MRI within 1 year after completion of standard radiation therapy for left-sided breast cancer.
The cardiac MRI scans will be evaluated to determine if there are changes in cardiac function within 1 year after radiation treatment.
Patients will be asked to complete a questionnaire before and after treatment that asks about their health and any symptoms they may be having.
Physical exams and any other standard of care service or treatment will be at the discretion of the treating physician.
- Ages 18 years old and older
- Left-sided breast cancer stage I-III
- Indications for adjuvant regional nodal and breast or chest wall radiation therapy (RT)
- Women and men are allowed
- Must be at least 18 years old at the time of consent
- Pregnant and/or breastfeeding women or patients of child-producing potential not willing to use contraception while on study
- Prior history of cardiovascular disease per physician discretion
- Stage 0 and IV breast cancer
- Prior radiation therapy to chest
- Concurrent trastuzumab per physician discretion
- Contraindications to cardiac MRI (e.g., contrast reaction, metal implants, etc.)
For questions about study details and eligibility, please contact Ashley Williams
KeywordsBreast cancer, Brain radiation - discharge, Neoplasm
Principal InvestigatorJulie Bradley, MD
Begin a new search for other research studies
Studies listed on this site have been approved by a UF Institutional Review Board (IRB), which works to ensure the welfare and rights of research participants as required by federal regulations. Study listings are provided by the UF Clinical and Translational Science Institute in collaboration with UF research teams and the UF IRBs.