Carl Pepine, M.D.

Carl J Pepine, M.D.

(352) 265-0820

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Carl J. Pepine, MD, is a doctor in the Division of Cardiovascular Medicine at the University of Florida College of Medicine. He graduated from the University of Pittsburgh in 1962 with his bachelor’s degree.

As he started medical school at Rutgers in New Jersey, Pepine stayed in the northeast for his internship at Allegheny General Hospital, a University of Pittsburgh affiliate. His two residencies were at Jefferson Medical College Hospital and Regional Naval Medical Center. He completed both fellowships in 1971 and became board certified in Internal Medicine.

He is currently a principal investigator of many NIH- and industry-funded research projects on cardiovascular disease in women, IHD, hypertension, heart failure, and cell-based therapy, with continuous peer-reviewed federal research funding (DoD, NIH, VA Merit) for over 40 years.

Pepine served as Chief of the UF Division of Cardiovascular Medicine from 1998–2008 and Chief of Cardiology, VA Medical Center, from 1978–1994. He has published more than 970 scientific publications, has edited 6 textbooks, and has been on the editorial boards of all major cardiovascular journals. He is the founding editor of Cardiology Today and Editor-in-Chief for American Heart Journal Plus: Cardiology Research and Practice. Pepine is currently the co-director of CTSI Multi-site Study Support Team at the National Center for Research.


Fellowship - Cardiopulmonary Physiology
Naval Hospital and Thomas Jefferson University

Residency - Internal Medicine
Naval Hospital

Residency - Internal Medicine
Thomas Jefferson University

Internship - Internal Medicine
Allegheny University Hospital

Medical Degree
Rutgers University

Undergraduate in Pre-Medical
University of Pittsburgh

Board Certification

  • Cardiovascular Disease - American Board of Internal Medicine
  • Diplomate - American Board of Internal Medicine
  • Diplomate - National Board of Medical Examiners

Honors and Awards

Wenger Award for Excellence in Medical research and Leadership
National Coalition for Women with Heart Disease

Lifetime Achievement Award
University of Florida

Best Doctors in America
Best Doctors in America

Best Doctors in America
Best Doctors in America

Outstanding Young Men of America
Outstanding Young Men of America