Carl Pepine, M.D.

Carl J Pepine, M.D.

(352) 265-0820

Request an Appointment

Publications

Treatment of coronary microvascular dysfunction
Cardiovascular Research
2020

Redefining Resistant Hypertension: A Comparison of Cardiovascular Risk Associated With the 2018 Versus 2008 American Heart Association Definitions for Resistant Hypertension
Circulation-Cardiovascular Quality and Outcomes
2020

Psychological stress, cardiac symptoms, and cardiovascular risk in women with suspected ischemia but no obstructive coronary disease (INOCA)
Stress and Health
2020

Oxidative Stress Is Associated With Diastolic Dysfunction in Women With Ischemia With No Obstructive Coronary Artery Disease
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2020

Not typical angina and mortality in women with obstructive coronary artery disease: Results from the Women's Ischemic Syndrome Evaluation study (WISE)
International journal of cardiology. Heart & vasculature
2020

Maternal Treatment With Captopril Persistently Alters Gut-Brain Communication and Attenuates Hypertension of Male Offspring
Hypertension
2020

Immune Dysregulation in HFpEF: A Target for Mesenchymal Stem/Stromal Cell Therapy
Journal of Clinical Medicine
2020

Heart failure with preserved ejection fraction: Similarities and differences between women and men.
International Journal of Cardiology
2020

Commentary - The ISCHEMIA trial.
International Journal of Cardiology
2020

Altered Gut Microbiome Profile in Patients With Pulmonary Arterial Hypertension
Hypertension
2020

Acute Stroke During Pregnancy and Puerperium
Journal of the American College of Cardiology
2020

Sex and Race/Ethnicity Differences in Atrial Fibrillation
Journal of the American College of Cardiology
2019

Sex Differences in Cardiovascular Disease and Cognitive Impairment: Another Health Disparity for Women?
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2019

Novel Self-Report Tool for Cardiovascular Risk Assessment
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2019

Mechanisms and diagnostic evaluation of persistent or recurrent angina following percutaneous coronary revascularization
European heart journal
2019

Impact of Abnormal Coronary Reactivity on Long-Term Clinical Outcomes in Women
Journal of the American College of Cardiology
2019

Genome-Wide Meta-Analysis of Blood Pressure Response to β1-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies)
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2019

Gender in cardiovascular medicine: chest pain and coronary artery disease
European heart journal
2019

Age at Menarche and Risk of Cardiovascular Disease Outcomes: Findings From the National Heart Lung and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2019

Adverse Pregnancy Outcomes Are Associated with Reduced Coronary Flow Reserve in Women With Signs and Symptoms of Ischemia Without Obstructive Coronary Artery Disease: A Report from the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study
Journal of Womens Health
2019

Why names matter for women: MINOCA/INOCA (myocardial infarction/ischemia and no obstructive coronary artery disease)
Clinical Cardiology
2018

Unanticipated Cardiotoxicity Associated With Targeted Anticancer Therapy in Patients With Hematologic Malignancies Patients: Natural History and Risk Factors
Cardiovascular Toxicology
2018

Rationale and Design of the Seneca (Stem Cell Injection in Cancer Survivors) Trial
American Heart Journal
2018

Rationale and Design of the Concert-Hf Trial (Combination of Mesenchymal and C-Kit(+) Cardiac Stem Cells As Regenerative Therapy for Heart Failure)

2018

Optimal medical treatment of hypertension in patients with coronary artery disease.
Expert Review of Cardiovascular Therapy
2018

Optimal Systolic Blood Pressure Target in Apparent Resistant and Non-Resistant Hypertension: A Pooled Analysis of Patient-Level Data from Sprint and ACCORD.
The American journal of medicine. Supplement
2018

Maladaptive Left Ventricular Remodeling in Women: An Analysis From the Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction Study
International Journal of Cardiology
2018

Late sodium channel blockade improves angina and myocardial perfusion in patients with severe coronary microvascular dysfunction: Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction ancillary study.
International Journal of Cardiology
2018

Ischemia and No Obstructive Coronary Artery Disease ( INOCA ): What Is the Risk?
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2018

Intensive Blood Pressure Lowering Reduces Adverse Cardiovascular Outcomes Among Patients With High-Normal Glucose: An Analysis From the Systolic Blood Pressure Intervention Trial Database
Journal of Clinical Hypertension
2018

Hypertension Across a Woman's Life Cycle
Journal of the American College of Cardiology
2018

Gut microbiota and serum metabolite differences in African Americans and White Americans with high blood pressure.
International Journal of Cardiology
2018

Genome-wide association analysis of common genetic variants of resistant hypertension.
The Pharmacogenomics Journal
2018

Extent of Coronary Atherosclerosis and Arterial Remodelling in Women: the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation
Cardiovascular Diagnosis and Therapy
2018

Typical angina is associated with greater coronary endothelial dysfunction but not abnormal vasodilatory reserve
Clinical Cardiology
2017

Ten-Year Mortality in the Wise Study (Women's Ischemia Syndrome Evaluation)
Circulation-Cardiovascular Quality and Outcomes
2017

Systolic blood pressure target: Have we identified the optimal target yet?
Journal of public health and emergency
2017

Sudden Cardiac Death in Women With Suspected Ischemic Heart Disease, Preserved Ejection Fraction, and No Obstructive Coronary Artery Disease: A Report From the Women's Ischemia Syndrome Evaluation Study
Journal of the American Heart Association. Cardiovascular and cerebrovascular disease
2017

Peripheral Blood Cytokine Levels After Acute Myocardial Infarction Il-1 Beta- and Il-6-Related Impairment of Bone Marrow Function

2017

Myocardial tissue deformation is reduced in subjects with coronary microvascular dysfunction but not rescued by treatment with ranolazine
Clinical Cardiology
2017

Migraine Headache and Long-Term Cardiovascular Outcomes: An Extended Follow-Up of the Women's Ischemia Syndrome Evaluation
American Journal of Medicine
2017

Ischemia and No Obstructive Coronary Artery Disease (Inoca) Developing Evidence-Based Therapies and Research Agenda for the Next Decade
Circulation
2017

Intestinal Permeability Biomarker Zonulin Is Elevated in Healthy Aging
Journal of the American Medical Directors Association
2017

Identification of Cardiovascular Risk Factors Associated With Bone Marrow Cell Subsets in Patients With Stemi: a Biorepository Evaluation From the Cctrn Time and Latetime Clinical Trials
Basic Research in Cardiology
2017

Fifteen New Risk Loci for Coronary Artery Disease Highlight Arterial-Wall-Specific Mechanisms
Nature Genetics
2017

Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: the Cctrn Pace Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells)
Circulation
2017

Effect of Low-Furanocoumarin Hybrid Grapefruit Juice Consumption on Midazolam Pharmacokinetics
The Journal of Clinical Pharmacology
2017

Daily Activity Measured With Wearable Technology As a Novel Measurement of Treatment Effect in Patients With Coronary Microvascular Dysfunction: Substudy of a Randomized Controlled Crossover Trial

2017

Aortic Flow Conditions Predict Ejection Efficiency in the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Cardiovascular Diagnosis and Therapy
2017

Use of Bio-Informatics Assessment Schema (Bias) to Improve Diagnosis and Prognosis of Myocardial Perfusion Data: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Cardiovascular Diagnosis and Therapy
2016

The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications
JACC. Basic to translational science
2016

Safety of Routine Invasive Versus Selective Invasive Therapy in Women With Non-St-Elevation Acute Coronary Syndrome

2016

Psychosocial Predictors of Long-Term Mortality Among Women With Suspected Myocardial Ischemia: the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation
Journal of Behavioral Medicine
2016

Mortality Risk Associated With Resistant Hypertension Among Women: Analysis From Three Prospective Cohorts Encompassing the Spectrum of Women's Heart Disease
Journal of Womens Health
2016

Genetic Loci Associated With Nonobstructive Coronary Artery Disease in Caucasian Women
Physiological Genomics
2016

Circulating Progenitor Cells and Coronary Microvascular Dysfunction: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction Study (Wise-Cvd)
Atherosclerosis
2016

Cardiovascular Disease and 10-Year Mortality in Postmenopausal Women With Clinical Features of Polycystic Ovary Syndrome
Journal of Womens Health
2016

Association Between High Endocardial Unipolar Voltage and Improved Left Ventricular Function in Patients With Ischemic Cardiomyopathy

2016

An Injectable Capillary-Like Microstructured Alginate Hydrogel Improves Left Ventricular Function After Myocardial Infarction in Rats
International Journal of Cardiology
2016

A Randomized, Placebo-Controlled Trial of Late Na Current Inhibition (Ranolazine) in Coronary Microvascular Dysfunction (Cmd): Impact on Angina and Myocardial Perfusion Reserve

2016

Renal Function and Coronary Microvascular Dysfunction in Women With Symptoms/Signs of Ischemia
PLoS One
2015

Multiple Causes for Ischemia Without Obstructive Coronary Artery Disease Not a Short List
Circulation
2015

Mild Renal Dysfunction and Long-Term Adverse Outcomes in Women With Chest Pain: Results From the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
American Heart Journal
2015

Microvascular Coronary Dysfunction and Ischemic Heart Disease: Where Are We in 2014?
Trends in Cardiovascular Medicine
2015

Impact of Aspirin According To Type of Stable Coronary Artery Disease: Insights From a Large International Cohort
American Journal of Medicine
2015

Gut Dysbiosis Is Linked To Hypertension
Hypertension
2015

Efficacy and Safety of Angiotensin Receptor Blockers in Older Patients: a Meta-Analysis of Randomized Trials
American Journal of Hypertension
2015

Effects of Verapamil Sr and Atenolol On 24-Hour Blood Pressure and Heart Rate in Hypertension Patients With Coronary Artery Disease: An International Verapamil Sr-Trandolapril Ambulatory Monitoring Substudy
PLoS One
2015

Cardiac Magnetic Resonance Myocardial Perfusion Reserve Index Is Reduced in Women With Coronary Microvascular Dysfunction a National Heart, Lung, and Blood Institute-Sponsored Study From the Women's Ischemia Syndrome Evaluation
Circulation-Cardiovascular Imaging
2015

Bone Marrow Characteristics Associated With Changes in Infarct Size After Stemi a Biorepository Evaluation From the Cctrn Time Trial

2015

Assessing Cardiovascular Risk in Women: Looking Beyond Traditional Risk Factors
Trends in Cardiovascular Medicine
2015

Angina Treatments and Prevention of Cardiac Events: An Appraisal of the Evidence
European Heart Journal Supplements
2015

Adverse Pregnancy Conditions, Infertility, and Future Cardiovascular Risk: Implications for Mother and Child
Cardiovascular Drugs and Therapy
2015

Timi Frame Count and Adverse Events in Women With No Obstructive Coronary Disease: a Pilot Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
PLoS One
2014

The Vascular Biology Working Group Twentieth Anniversary

2014

Relationships Between Depression, Dietary Habits, and Cardiovascular Mortality and Events Among Women With Suspected Myocardial Ischemia
Psychosomatic Medicine
2014

Proceedings From Duke Resistant Hypertension Think Tank
American Heart Journal
2014

Predictors and Outcomes of Resistant Hypertension Among Patients With Coronary Artery Disease and Hypertension
Journal of Hypertension
2014

One-year follow-up of intracoronary stem cell delivery on left ventricular function following ST-elevation myocardial infarction
Jama-Journal of the American Medical Association
2014

Large-Scale Gene-Centric Analysis Identifies Polymorphisms for Resistant Hypertension

2014

Detailed Analysis of Bone Marrow From Patients With Ischemic Heart Disease and Left Ventricular Dysfunction Bm Cd34, Cd11B, and Clonogenic Capacity as Biomarkers for Clinical Outcomes

2014

Depression, dietary habits, and cardiovascular events among women with suspected myocardial ischemia
American Journal of Medicine
2014

Comparison of Low and High Dose Intracoronary Adenosine and Acetylcholine in Women Undergoing Coronary Reactivity Testing: Results From the Nhlbi-Sponsoredwomen's Ischemia Syndrome Evaluation (Wise)
International Journal of Cardiology
2014

Cardiovascular and Mortality Risk of Apparent Resistant Hypertension in Women With Suspected Myocardial Ischemia: a Report From the Nhlbi-Sponsored Wise Study

2014

Bone Marrow Mononuclear Cell Therapy for Acute Myocardial Infarction a Perspective From the Cardiovascular Cell Therapy Research Network

2014

Atp2B1 Locus Is Associated With Resistant Hypertension in the International Verapamil Sr Tandolapril Study-Genetic Substudy (Investgenes)
Clinical Pharmacology & Therapeutics
2014

Aldosterone Inhibition and Coronary Endothelial Function in Women Without Obstructive Coronary Artery Disease: An Ancillary Study of the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation
American Heart Journal
2014

A Pharmacogenomic Genome-Wide Association Study for Adverse Cardiovascular Outcomes in the International Verapamil Sr-Trandolapril Study (Invest)
Clinical Pharmacology & Therapeutics
2014

A Pharmacogenomic Genome-Wide Association Study (Gwas) for New Onset Diabetes (Nod) in the International Verapamil Sr-Trandolapril Study (Invest)
Clinical Pharmacology & Therapeutics
2014

A Microvascular-Myocardial Diastolic Dysfunctional State and Risk for Mental Stress Ischemia a Revised Concept of Ischemia During Daily Life
Jacc-Cardiovascular Imaging
2014

2014 Hypertension Recommendations From the Eighth Joint National Committee Panel Members Raise Concerns for Elderly Black and Female Populations
Journal of the American College of Cardiology
2014

2014 Eighth Joint National Committee Panel Recommendation for Blood Pressure Targets Revisited Results From the Invest Study
Journal of the American College of Cardiology
2014

Variable and Decreased Clonogenic Activity of Autologous Bone Marrow in Cell Therapy Patients With Ischemic Heart Disease, and Cd34 as a Biomarker for Clinical Outcomes: Results From the Cardiovascular Cell Therapy Research Network (Cctrn)
Circulation
2013

The Nhlbi Time Trial: One-Year Results
Circulation
2013

The Editor's Roundtable: the 10Q Report-Advancing Women's Heart Health Through Improved Research, Diagnosis, and Treatment
American Journal of Cardiology
2013

Simple Integer Risk Score To Determine Prognosis of Patients With Hypertension and Chronic Stable Coronary Artery Disease

2013

Phase II Clinical Research Design in Cardiology Learning the Right Lessons Too Well: Observations and Recommendations From the Cardiovascular Cell Therapy Research Network (Cctrn)
Circulation
2013

Pharmacogenomic Association of Nonsynonymous Snps in Siglec12, A1Bg, and the Selectin Region and Cardiovascular Outcomes
Hypertension
2013

Oxidative Stress Independently Predicts Diastolic Dysfunction in Women With Signs and Symptoms of Ischemia Without Obstructive Coronary Artery Disease: Results From the Nhlbi-Sponsored Women Ischemia Syndrome Evaluation (Wise)
Circulation
2013

Number and Function of Bone-Marrow Derived Angiogenic Cells and Coronary Flow Reserve in Women Without Obstructive Coronary Artery Disease: a Substudy of the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
PLoS One
2013

Mortality Implications of Angina and Blood Pressure in Hypertensive Patients With Coronary Artery Disease: New Data From Extended Follow-Up of the International Verapamil/Trandolapril Study (Invest)
Clinical Cardiology
2013

Mild Renal Insufficiency Predicts Mortality and Adverse Events in Women With Cardiac Ischemia, Independent of the Underlying Obstructive Coronary Artery Disease
Circulation
2013

Mild Renal Insufficiency Is An Independent Predictor of Coronary Microvascular Dysfunction Among Women With Symptoms/Signs of Ischemia: a Report From the Women's Ischemia Syndrome Evaluation (Wise)
Circulation
2013

Lack of Association of the Hmga1 Ivs5-13Insc Variant With Type 2 Diabetes in An Ethnically Diverse Hypertensive Case Control Cohort

2013

Increased Wave Reflection and Ejection Duration in Women With Chest Pain and Nonobstructive Coronary Artery Disease: Ancillary Study From the Women's Ischemia Syndrome Evaluation
Journal of Hypertension
2013

Increased Circulating Progenitor Cells in Women With Microvascular Coronary Dysfunction: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction Study (Wise-Cvd)
Circulation
2013

Improved diagnosis and prognosis using Decisions Informed by Combining Entities (DICE): results from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE)
Cardiovascular Diagnosis and Therapy
2013

Impact of Tcf7L2 Single Nucleotide Polymorphisms On Hydrochlorothiazide-Induced Diabetes
Pharmacogenetics and Genomics
2013

Genetic Variation in Pear1 Is Associated With Platelet Aggregation and Cardiovascular Outcomes
Circulation-Cardiovascular Genetics
2013

Enhancing the Function of Cd34(+) Cells By Targeting Plasminogen Activator Inhibitor-1
PLoS One
2013

Electromechanical Assessment of Myocardial Function Is Associated With Improvement in Ejection Fraction in Patients Treated With Autologous Stem Cell Therapy for Ischemic Cardiomyopathy
Circulation
2013

Electromechanical Assessment of Myocardial Function (Noga) Is Associated With Exercise Improvement in Patients Treated With Autologous Stem Cell Therapy for Refractory Angina
Journal of the American College of Cardiology
2013

Detailed Analysis of Polymer Response To Delivery Balloon Expansion of Drug-Eluting Stents Versus Bare Metal Stents

2013

Coronary Angiography Is It Time To Reassess?
Circulation
2013

Clinical implications of the Women's Ischemia Syndrome Evaluation: inter-relationships between symptoms, psychosocial factors and cardiovascular outcomes
Womens Health
2013

Calcium Antagonists in the Treatment of Coronary Artery Disease
Current Opinion in Pharmacology
2013

Brachial Artery Constriction During Brachial Artery Reactivity Testing Predicts Major Adverse Clinical Outcomes in Women With Suspected Myocardial Ischemia: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise) Study
PLoS One
2013

Body Composition Changes and Cardiometabolic Benefits of a Balanced Italian Mediterranean Diet in Obese Patients With Metabolic Syndrome
Acta Diabetologica
2013

Association of Variants in Nedd4L With Blood Pressure Response and Adverse Cardiovascular Outcomes in Hypertensive Patients Treated With Thiazide Diuretics
Journal of Hypertension
2013

Association of Kcnj1 Variation With Change in Fasting Glucose and New Onset Diabetes During Hctz Treatment
Pharmacogenomics Journal
2013

Association Between the Chromosome 9P21 Locus and Angiographic Coronary Artery Disease Burden a Collaborative Meta-Analysis
Journal of the American College of Cardiology
2013

Anxiety Associations With Cardiac Symptoms, Angiographic Disease Severity, and Healthcare Utilization: the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation
International Journal of Cardiology
2013

Antagonist Molecules in the Treatment of Angina
Expert Opinion on Pharmacotherapy
2013

Adverse Outcomes Among Women Presenting With Signs and Symptoms of Ischemia and No Obstructive Coronary Artery Disease: Findings From the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise) Angiographic Core Laboratory
American Heart Journal
2013

A Critical Analysis of Clinical Outcomes Reported in Stem Cell Trials for Acute Myocardial Infarction: Some Thoughts for Design of Future Trials
Current Atherosclerosis Reports
2013

Treatment-Resistant Blood Pressure Among Patients With Coronary Artery Disease - Cause for Concern: New Data From the Extended Follow-Up of the International Verapamail Sr-Trandolapril Study (Invest)
Journal of the American College of Cardiology
2012

Treatment of Hypertension Lower Is Better, Or Is It?
Hypertension
2012

The Effect of Timing of Stem Cell Delivery Following Acute Myocardial Infarction: the Nhlbi and Cctrn Time Trial
Circulation
2012

Simple Prediction of Long-Term Mortality Among Hypertensive Patients With Coronary Artery Disease: New Data From An Extended Follow-Up of the International Verapamil-Sr/Trandolapril Study (Invest)
Journal of the American College of Cardiology
2012

Safety of Coronary Reactivity Testing in Women With No Obstructive Coronary Artery Disease
Jacc-Cardiovascular Interventions
2012

Rethinking Stable Ischemic Heart Disease Is This the Beginning of a New Era?
Journal of the American College of Cardiology
2012

Relationships Between Components of Metabolic Syndrome and Coronary Intravascular Ultrasound (Ivus) Atherosclerosis Measures in Women Without Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation (Wise) Study
Journal of the American College of Cardiology
2012

Relationships Between Cardiovascular Disease Risk Factors and Depressive Symptoms as Predictors of Cardiovascular Disease Events in Women
Journal of Womens Health
2012

Non-Synonymous Snps in Sele, Selp, and Siglec12 Associate With Cardiovascular (Cv) Outcomes in the International Verapamil Sr-Trandol-April Study Genetic Substudy (Invest-Genes)
Clinical Pharmacology & Therapeutics
2012

Mortality Associated With Angina and Blood Pressure Control Among Hypertensive Patients With Coronary Artery Disease: New Data From Extended Follow-Up of the International Verapamil/Trandolapril Study
Journal of the American College of Cardiology
2012

Intracoronary Bone Marrow Mononuclear Cells After Myocardial Infarction Reply
Jama-Journal of the American Medical Association
2012

G Protein Receptor Kinase 4 Polymorphisms Beta-Blocker Pharmacogenetics and Treatment-Related Outcomes in Hypertension
Hypertension
2012

Effect of the Use and Timing of Bone Marrow Mononuclear Cell Delivery On Left Ventricular Function After Acute Myocardial Infarction the Time Randomized Trial
Jama-Journal of the American Medical Association
2012

Effect of Transendocardial Delivery of Autologous Bone Marrow Mononuclear Cells On Functional Capacity, Left Ventricular Function, and Perfusion in Chronic Heart Failure the Focus-Cctrn Trial
Jama-Journal of the American Medical Association
2012

Differential Effects of Cold Pressor and Acetylcholine During Endothelial Function Assessment in Women With No Obstructive Coronary Artery Disease: the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation (Wise) Study
Journal of the American College of Cardiology
2012

Damage To Polymer Surface and Detachment of Polymer Fragments During Delivery Balloon Expansion of Drug-Eluting Stents: A Previously Unrecognized Source for Adverse Outcomes
Journal of the American College of Cardiology
2012

Comparing Marginal Structural Models To Standard Methods for Estimating Treatment Effects of Antihypertensive Combination Therapy
Bmc Medical Research Methodology
2012

Combining Psychosocial Data To Improve Prediction of Cardiovascular Disease Risk Factors and Events: the National Heart, Lung, and Blood Institute-Sponsored Women'S Ischemia Syndrome Evaluation Study
Psychosomatic Medicine
2012

Cholesteryl Ester Transfer Protein (Cetp) Polymorphisms Affect Mrna Splicing, Hdl Levels, and Sex-Dependent Cardiovascular Risk
PLoS One
2012

Cell Tracking and the Development of Cell-Based Therapies a View From the Cardiovascular Cell Therapy Research Network
Jacc-Cardiovascular Imaging
2012

An Injectable Acellular Capillary Hydrogel Improves Left Ventricular Function After Myocardial Infarction
Journal of the American College of Cardiology
2012

Alpha Adducin-1 (Add1)Singlenucleotide Polymorphism (Snp) Associated With New Onset Diabetes Risk With Hydrochlorothiazide (Hctz) Therapy in the International Verapamil Sr Trandolapril Genetic Substudy (Invest-Genes)
Clinical Pharmacology & Therapeutics
2012

A Degradable, Bioactive, Gelatinized Alginate Hydrogel To Improve Stem Cell/Growth Factor Delivery and Facilitate Healing After Myocardial Infarction
Medical Hypotheses
2012

What Causes Myocardial Infarction in Women Without Obstructive Coronary Artery Disease?
Circulation
2011

Timing of Hormone Therapy, Type of Menopause, and Coronary Disease in Women: Data From the National Heart, Lung, and Blood Institute-Sponsored Women'S Ischemia Syndrome Evaluation
Menopause-the Journal of the North American Menopause Society
2011

Syndrome X and Microvascular Coronary Dysfunction
Circulation
2011

Results From Latetime: a Randomized, Placebo Controlled Trial of Intracoronary Stem Cell Delivery Two To Three Weeks Following Acute Myocardial Infarction
Circulation
2011

Response To Letter Regarding Article "Chromosome 9P21 Haplotypes and Prognosis in White and Black Patients With Coronary Artery Disease"
Circulation-Cardiovascular Genetics
2011

Relationship Between Coronary Micro- and Macrovascular Measures in Women With Chest Pain Without Significant Coronary Artery Disease: An Ancillary Substudy From the Nhbli-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of the American College of Cardiology
2011

Quantification of Myocardial Segmental Function in Acute and Chronic Ischemic Heart Disease and Implications for Cardiovascular Cell Therapy Trials a Review From the Nhlbi-Cardiovascular Cell Therapy Research Network
Jacc-Cardiovascular Imaging
2011

Polymorphisms in Genes Coding for Grk2 and Grk5 and Response Differences in Antihypertensive-Treated Patients
Pharmacogenetics and Genomics
2011

Liver X Receptor a Gene Polymorphisms and Variable Cardiovascular Outcomes in Patients Treated With Antihypertensive Therapy: Results From the Invest-Genes Study
Pharmacogenetics and Genomics
2011

Kcnj1 Snps Are Associated With Increased Fasting Glucose and Risk of New Onset Diabetes During Hctz Therapy
Clinical Pharmacology & Therapeutics
2011

Intramyocardial, Autologous Cd34+Cell Therapy for Refractory Angina

2011

In Women With Symptoms of Cardiac Ischemia, Nonobstructive Coronary Arteries, and Microvascular Dysfunction, Angiotensin-Converting Enzyme Inhibition Is Associated With Improved Microvascular Function: a Double-Blind Randomized Study From the National Heart, Lung and Blood Institute Women'S Ischemia Syndrome Evaluation (Wise)
American Heart Journal
2011

Harmful Effects of Nsaids Among Patients With Hypertension and Coronary Artery Disease
American Journal of Medicine
2011

Genetic Variation in the Calcium Signaling Pathway and Association With Outcomes in Hypertensive Coronary Artery Disease Patients
Clinical Pharmacology & Therapeutics
2011

Efficacy of Fenofibric Acid Plus Statins On Multiple Lipid Parameters and Its Safety in Women With Mixed Dyslipidemia
American Journal of Cardiology
2011

Effect of Phosphodiesterase Type 5 Inhibition On Microvascular Coronary Dysfunction in Women: a Women's Ischemia Syndrome Evaluation (Wise) Ancillary Study
Clinical Cardiology
2011

Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 To 3 Weeks Following Acute Myocardial Infarction On Left Ventricular Function the Latetime Randomized Trial
Jama-Journal of the American Medical Association
2011

Does Angiotensin Plus Aldosterone Inhibition Improve Coronary Endothelial Function? An Ancillary Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of the American College of Cardiology
2011

Developing Mechanistic Insights Into Cardiovascular Cell Therapy: Cardiovascular Cell Therapy Research Network Biorepository Core Laboratory Rationale
American Heart Journal
2011

Could Retinal Imaging Provide a Simple, Inexpensive, Noninvasive Index for Coronary Microvascular Function in Women With Chest Pain and Nonobstructive Coronary Artery Disease? An Ancillary Pilot Study From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise-Aric)
Journal of the American College of Cardiology
2011

Chromosome 9p21 Haplotypes and Prognosis in White and Black Patients with Coronary Artery Disease
Circulation-Cardiovascular Genetics
2011

Blood Pressure Lowering in Patients With Diabetes-One Level Might Not Fit All

2011

Tight Blood Pressure Control and Cardiovascular Outcomes Among Hypertensive Patients With Diabetes and Coronary Artery Disease
Jama-Journal of the American Medical Association
2010

The use of diuretics plus calcium channel blockers for hypertension may be associated with a higher risk of myocardial infarction but not stroke compared with the combination of diuretics plus beta blockers.
Evidence-Based Medicine
2010

Self-Rated Versus Objective Health Indicators as Predictors of Major Cardiovascular Events: the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation
Psychosomatic Medicine
2010

Residual Risk for Secondary Ischemic Events in Patients With Atherothrombotic Disease: Opportunity for Future Improvements in Patient Care
Annals of Medicine
2010

Prognostic Value of Global Mr Myocardial Perfusion Imaging in Women With Suspected Myocardial Ischemia and No Obstructive Coronary Disease Results From the Nhlbi-Sponsored Wise (Women's Ischemia Syndrome Evaluation) Study
Jacc-Cardiovascular Imaging
2010

Prognostic Utility of Quantifying Evolutionary St-Segment Depression On Early Follow-Up Electrocardiogram in Patients With Non-St-Segment Elevation Acute Coronary Syndromes

2010

Pathophysiologic mechanisms linking impaired cardiovascular health and neurologic dysfunction: the year in review.

2010

Outcomes Among Hypertensive Patients With Concomitant Peripheral and Coronary Artery Disease Findings From the International Verapamil-Sr/Trandolapril Study
Hypertension
2010

New-Onset Diabetes Risk Associated With Antihypertensive Therapy in Hypertensive Coronary Artery Disease Patients Is Modified By a Single Nucleotide Polymorphism (Snp) in the L-Type Calcium Channel (Ltcc)
Clinical Pharmacology & Therapeutics
2010

Multicenter Cell Processing for Cardiovascular Regenerative Medicine Applications: the Cardiovascular Cell Therapy Research Network (Cctrn) Experience
Cytotherapy
2010

Identifying Patients At High Risk of a Cardiovascular Event in the Near Future Current Status and Future Directions: Report of a National Heart, Lung, and Blood Institute Working Group
Circulation
2010

Hypertension Control and Cardiovascular Outcomes Among Patients With Diabetes and Coronary Artery Disease Reply
Jama-Journal of the American Medical Association
2010

Genetic Variation in the Beta 2 Subunit of the Voltage-Gated Calcium Channel and Pharmacogenetic Association With Adverse Cardiovascular Outcomes in the International Verapamil Sr-Trandolapril Study Genetic Substudy (Invest-Genes)
Circulation-Cardiovascular Genetics
2010

Endothelium as a Predictor of Adverse Outcomes
Clinical Cardiology
2010

Dhea-S Levels and Cardiovascular Disease Mortality in Postmenopausal Women: Results From the National Institutes of Health-National Heart, Lung, and Blood Institute (Nhlbi)-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
The Journal of Clinical Endocrinology and Metabolism
2010

Development of a Network To Test Strategies in Cardiovascular Cell Delivery: the Nhlbi-Sponsored Cardiovascular Cell Therapy Research Network (Cctrn)
Journal of Cardiovascular Translational Research
2010

Coronary revascularization strategy and outcomes according to blood pressure (from the International Verapamil SR-Trandolapril Study [INVEST]).
American Journal of Cardiology
2010

Coronary Microvascular Reactivity To Adenosine Predicts Adverse Outcome in Women Evaluated for Suspected Ischemia Results From the National Heart, Lung and Blood Institute Wise (Women's Ischemia Syndrome Evaluation) Study
Journal of the American College of Cardiology
2010

Combination Rosuvastatin Plus Fenofibric Acid in a Cohort of Patients 65 Years Or Older With Mixed Dyslipidemia: Subanalysis of Two Randomized, Controlled Studies
Clinical Cardiology
2010

Clinical Association of Variation in the Beta 2 Regulatory Subunit of the Voltage- Gated Calcium Channel (Cacnb2) With Outcomes in Hypertensive Coronary Artery Disease (Cad) Patients.
Clinical Pharmacology & Therapeutics
2010

Clinical Association of Variation in the Beta 2 Regulatory Subunit of the Voltage- Gated Calcium Channel ( Cacnb2) With Outcomes in Hypertensive Coronary Artery Disease ( Cad) Patients.
Clinical Pharmacology & Therapeutics
2010

Bone marrow-derived cells and hypertension
Expert Review of Cardiovascular Therapy
2010

Blood pressure and outcomes in very old hypertensive coronary artery disease patients: an INVEST substudy.
The American journal of medicine. Supplement
2010

Aromatase Gene Polymorphisms Are Associated With Survival Among Patients With Cardiovascular Disease in a Sex-Specific Manner
PLoS One
2010

An Intravascular Ultrasound Analysis in Women Experiencing Chest Pain in the Absence of Obstructive Coronary Artery Disease: a Substudy From the National Heart, Lung and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of Interventional Cardiology
2010

A Randomized Controlled, Phase 2 Trial of the Viral Serpin Serp-1 in Patients With Acute Coronary Syndromes Undergoing Percutaneous Coronary Intervention

2010

A Randomized Controlled Trial of Low-Dose Hormone Therapy On Myocardial Ischemia in Postmenopausal Women With No Obstructive Coronary Artery Disease: Results From the National Institutes of Health/National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
American Heart Journal
2010

Viral Anti-Inflammatory Treatment of Unstable Coronary Syndromes: the Vt-111 Acute Coronary Syndrome Trial
Circulation
2009

Transient Blockade of Tgf-Beta in Hematopoietic Stem Cells and Cd34+Endothelial Precursor Cells Enhances Survival, Proliferation and Reparative Functions in Response To Ischemic Vascular Injury
Circulation
2009

Total Estrogen Time and Obstructive Coronary Disease in Women: Insights From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise)
Journal of Womens Health
2009

Time From Onset of Acute Anterior Myocardial Infarction Negatively Influences Bone Marrow Cell Function: Preliminary Data From the Nhlbi Cctrn Ancillary Studies
Circulation
2009

The Potential Role of Nitric Oxide in Cardiovascular Safety When Treating Patients With Osteoarthritis and Hypertension: a Moderated Panel Discussion
American Journal of Medicine
2009

The Impact of Nitric Oxide in Cardiovascular Medicine: Untapped Potential Utility
The American journal of medicine. Supplement
2009

Systolic Blood Pressure and Subjective Well-Being in Patients With Coronary Artery Disease
Clinical Cardiology
2009

Sudden Cardiac Death and Severity of Obstructive Coronary Artery Disease: a Report From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise) Study
Circulation
2009

Rationale and Design for Time: a Phase Ii, Randomized, Double-Blind, Placebo-Controlled Pilot Trial Evaluating the Safety and Effect of Timing of Administration of Bone Marrow Mononuclear Cells After Acute Myocardial Infarction
American Heart Journal
2009

Pulse Pressure and Risk of Cardiovascular Outcomes in Patients With Hypertension and Coronary Artery Disease: An International Verapamil Sr-Trandolapril Study (Invest) Analysis

2009

Promoter Polymorphisms in Ace (Angiotensin I-Converting Enzyme) Associated With Clinical Outcomes in Hypertension
Clinical Pharmacology & Therapeutics
2009

Pediatric Atorvastatin in Diabetes Trial (Padit): a Pilot Study To Determine the Effect of Atorvastatin On Arterial Stiffness and Endothelial Function in Children With Type 1 Diabetes Mellitus
Journal of Pediatric Endocrinology & Metabolism
2009

Pediatric Atorvastatin in Diabetes Trial (PADIT): a pilot study to determine the effect of atorvastatin on arterial stiffness and endothelial function in children with type 1 diabetes mellitus.
Journal of Pediatric Endocrinology & Metabolism
2009

Noninvasive Pressure Waveform Analysis in Women With Chest Pain and Nonobstructive Coronary Artery Disease
Journal of the American College of Cardiology
2009

Multimarker Approach Predicts Adverse Cardiovascular Events in Women Evaluated for Suspected Ischemia: Results From the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation
Clinical Cardiology
2009

Long-Term Mortality Associated With New Onset Diabetes in Hypertensive Cad Patients Following Exposure To Antihypertensive Medications: Findings From the International Verapamail Sr-Trandolapril Study (Invest)
Journal of the American College of Cardiology
2009

Insulin as a Cardiovascular Therapeutic: Improving Glycemic Control in Patients With Coronary Artery Disease
Journal of the American College of Cardiology
2009

Incident Or Continued Angina During Hypertension Treatment Is Associated With Increased Risk of Death, Mi, Or Stroke Among Patients With Known Cad: a Substudy of the International Verapamil/Trandolapril Study (Invest)
Circulation
2009

Importance of Blood Pressure Control in Hypertensive Patients With Coronary Heart Disease in Clinical Practice To Reduce the Risk of Stroke Response
Stroke
2009

INVEST revisited: review of findings from the International Verapamil SR-Trandolapril Study.
Expert Review of Cardiovascular Therapy
2009

Genetic and Pharmacogenetic Associations Between Nos3 Polymorphisms, Blood Pressure, and Cardiovascular Events in Hypertension
American Journal of Hypertension
2009

Efficacy and Safety of Fenofibric Acid in Combination With a Statin in Patients With Mixed Dyslipidemia: Pooled Analysis of Three Phase 3, 12-Week Randomized, Controlled Studies
Journal of Clinical Lipidology
2009

Efficacy and Safety of Abt-335 (Fenofibric Acid) in Combination With Simvastatin in Patients With Mixed Dyslipidemia: a Phase 3, Randomized, Controlled Study
American Heart Journal
2009

Comorbid Depression and Anxiety Symptoms as Predictors of Cardiovascular Events: Results From the Nhlbi-Sponsored Women's Ischemia Syndrome Evaluation (Wise) Study
Psychosomatic Medicine
2009

Characteristics and Outcomes of Revascularized Patients With Hypertension An International Verapamil Sr-Trandolapril Substudy
Hypertension
2009

Cardiovascular Therapies and Associated Glucose Homeostasis Implications Across the Dysglycemia Continuum
Journal of the American College of Cardiology
2009

Cacna1C Gene Polymorphisms, Cardiovascular Disease Outcomes, and Treatment Response
Circulation-Cardiovascular Genetics
2009

Adverse Cardiovascular Outcomes in Women With Nonobstructive Coronary Artery Disease a Report From the Women's Ischemia Syndrome Evaluation Study and the St James Women Take Heart Project
Archives of Internal Medicine
2009

Weight Change With Beta-Blocker Use: a Side Effect Put Into Perspective - the Reply
American Journal of Medicine
2008

Verapamil-Sustained Release-Based Treatment Strategy Is Equivalent To Atenolol-Based Treatment Strategy At Reducing Cardiovascular Events in Patients With Prior Myocardial Infarction: An International Verapamil Sr-Trandolapril (Invest) Substudy
American Heart Journal
2008

Response To the J-Point Revisited
Hypertension
2008

Pulse Pressure and Adverse Outcomes in Women: a Report From the Women'S Ischemia Syndrome Evaluation (Wise)
American Journal of Hypertension
2008

Provoked Coronary Spasm and Acute Coronary Syndromes
Journal of the American College of Cardiology
2008

Prognostic Significance of Evolving St-Segment Depression On Admission and Early Repeat Electrocardiograms in Non-St Elevation Acute Coronary Syndromes - Insights From the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein Ilb/Illa Inhibitor (Synergy) Trial
Circulation
2008

Predicting Stroke Risk in Hypertensive Patients With Coronary Artery Disease - a Report From the Invest
Stroke
2008

Postmenopausal Women With a History of Irregular Menses and Elevated Androgen Measurements At High Risk for Worsening Cardiovascular Event-Free Survival: Results From the National Institutes of Health - National Heart, Lung, and Blood Institute Sponsored Women'S Ischemia Syndrome Evaluation
The Journal of Clinical Endocrinology and Metabolism
2008

Postmarket Evaluation of Breakthrough Technologies
American Heart Journal
2008

Novel Promoter Polymorphisms in Angiotensin-I Converting Enzyme (Ace) Associated With Clinical Outcomes in Hypertensive Coronary Artery Disease (Cad) Patients.
Clinical Pharmacology & Therapeutics
2008

Nos3 Polymorphisms Do Not Associate With Adverse Clinical Outcomes in Elderly Hypertensives With Coronaryartery Disease: Analysis of the International Verapamil Sr-Trandolapril Study Genetic Substudy (Invest-Genes).
Clinical Pharmacology & Therapeutics
2008

Marrow Cell Therapies for Cardiovascular Diseases
Experimental Hematology
2008

Madd Variants and Risk of Cardiovascular Events in the International Verapamil Sr/Trandolapril Study - Genetic Substudy (Invest Genes).
Clinical Pharmacology & Therapeutics
2008

Liver X Receptor-Alpha Gene Variability and Cardiovascular Risk in the International Verapamil Sr/Trandolapril Study - Genetic Substudy (Invest-Genes).
Clinical Pharmacology & Therapeutics
2008

Importance of Socioeconomic Status as a Predictor of Cardiovascular Outcome and Costs of Care in Women With Suspected Myocardial Ischemia. Results From the National Institutes of Health, National Heart, Lung and Blood Institute-Sponsored Women'S Ischemia Syndrome Evaluation (Wise)
Journal of Womens Health
2008

Impact of Resting Heart Rate On Outcomes in Hypertensive Patients With Coronary Artery Disease: Findings From the International Verapamil-Sr/Trandolapril Study (Invest)

2008

Dysglycemia During Treatment With Hctz in Patients With Hypertension and Metabolic Syndrome
Circulation
2008

Dna Variations in Voltage-Gated Calcium Channel Beta 2 Subunit (Cacnb2) Gene, Functional Consequences, and Association With Adverse Cardiovascular Outcomes in the International Verapamil Sr-Trandolapril Study-Genetic Substudy
Circulation
2008

Diabetes Risk Associated With Beta 1-Adrenergic Receptor Polymorphisms Differs By Antihypertensive Drug Therapy: Results From the International Verapamil Sr/Trandolapril Study - Genetic Substudy (Invest-Genes).
Clinical Pharmacology & Therapeutics
2008

Clinical and Research Issues Regarding Chronic Advanced Coronary Artery Disease: Part I: Contemporary and Emerging Therapies
American Heart Journal
2008

Cacnaic Polymorphisms and Cardiovascular Outcomes in the International Verapamil Sr/Trandolapril Study-Genetic Substudy (Invest-Genes).
Clinical Pharmacology & Therapeutics
2008

Blood Pressure Targets After High-Risk Myocardial Infarction - Is It Time To Update the Guidelines?
Hypertension
2008

Beta-Adrenergic Receptor Gene Polymorphisms and Beta-Blocker Treatment Outcomes in Hypertension
Clinical Pharmacology & Therapeutics
2008

Alpha-Adducin Polymorphism Associated With Increased Risk of Adverse Cardiovascular Outcomes: Results From Genetic Substudy of the International Verapamil Sr-Trandolapril Study (Invest-Genes)
American Heart Journal
2008

Adrenergic Gene Polymorphisms and Cardiovascular Risk in the Nhlbi-Sponsored Women'S Ischemia Syndrome Evaluation

2008

The pathophysiology of chronic ischemic heart disease.
Clinical Cardiology
2007

Phytoestrogens and coronary microvascular function in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE) Study.
Journal of Womens Health
2007

Metabolic syndrome and cardiovascular disease: challenges and opportunities.
Clinical Cardiology
2007

Influence of Hispanic ethnicity on blood pressure control and cardiovascular outcomes in women with CAD and hypertension: findings from INVEST.
Journal of Womens Health
2007

Some thoughts on the vasculopathy of women with ischemic heart disease.
Journal of the American College of Cardiology
2006

Predictors of adverse outcome among patients with hypertension and coronary artery disease.
Journal of the American College of Cardiology
2006

Introduction: there is an important need for increased understanding of the pathophysiology of heart failure postinfarction, new treatment strategies, earlier implementation of effective strategies, and more effective use of existing therapies.
American Journal of Cardiology
2006

Impaired coronary vascular reactivity and functional capacity in women: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE) Study.
Journal of the American College of Cardiology
2006

Depressive symptoms in coronary artery disease patients after hypertension treatment.
Annals of Pharmacotherapy
2006

Blood pressure control and cardiovascular outcomes in high-risk Hispanic patients--findings from the International Verapamil SR/Trandolapril Study (INVEST).
American Heart Journal
2006

An academic-community cardiovascular service line affiliation: design, implementation, and performance.
American Heart Journal
2006

Association between beta-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study
International Journal of Obesity
2005

Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in women.
Jama-Journal of the American Medical Association
2004

Ischemic heart disease: metabolic approaches to management.
Clinical Cardiology
2004

Ischemic heart disease in women: facts and wishful thinking.
Journal of the American College of Cardiology
2004

Education: nationally achievable solutions
Clinical Cornerstone
2004

Characteristics of contemporary patients with hypertension and coronary artery disease.
Clinical Cardiology
2004

Cardiovascular therapies and risk for development of diabetes.
Journal of the American College of Cardiology
2004

The role of carnitine in myocardial dysfunction.

2003

Optimizing lipid management in patients with acute coronary syndromes.
American Journal of Cardiology
2003

Introduction: new and emerging implications for the field of vascular biology.
American Journal of Cardiology
2003

Effects of angiotensin-converting enzyme inhibition on transient ischemia: the Quinapril Anti-Ischemia and Symptoms of Angina Reduction (QUASAR) trial.
Journal of the American College of Cardiology
2003

Revisiting the culprit lesion in non-Q-wave myocardial infarction. Results from the VANQWISH trial angiographic core laboratory.
Journal of the American College of Cardiology
2002

Mental stress-induced ischemia and all-cause mortality in patients with coronary artery disease: Results from the Psychophysiological Investigations of Myocardial Ischemia study.
Circulation
2002

Why vascular biology matters.
American Journal of Cardiology
2001

Sex differences in chest pain in patients with documented coronary artery disease and exercise-induced ischemia: Results from the PIMI study.
American Heart Journal
2001

Interventions in cardiology: focus on lipid management in acute and long-term settings.
American Journal of Cardiology
2001

Enhancing Clinical Trials on the Internet: Lessons from INVEST
Clinical Cardiology
2001

Effects of beta1-adrenoceptor genetic polymorphisms on resting hemodynamics in patients undergoing diagnostic testing for ischemia
American Journal of Cardiology
2001

Neuroendocrine activation in heart failure is modified by endurance exercise training.
Journal of the American College of Cardiology
1999

Rationale and design of the International Verapamil SR/Trandolapril Study (INVEST): an Internet-based randomized trial in coronary artery disease patients with hypertension.
Journal of the American College of Cardiology
1998

Rationale and Design of the International Verapamil SR/Trandolapril Study (INVEST): An Internet-Based Randomized Trial in Coronary Artery Disease Patients with Hypertension
Journal of the American College of Cardiology
1998

Endothelial dysfunction and its role in the cycle of cardiovascular disease.
Canadian Journal of Cardiology
1998

Angiotensin-converting enzyme inhibitors in patients with atherosclerosis and preserved left ventricular function: clinical outcomes.
Canadian Journal of Cardiology
1998

Effects of intermittent transdermal nitroglycerin on occurrence of ischemia after patch removal: results of the second transdermal intermittent dosing evaluation study (TIDES-II).
Journal of the American College of Cardiology
1997

Research Interests

Dr. Pepine is an internationally recognized leader in both the clinical and scientific areas of cardiovascular medicine. His major interests focus on the pathophysiology of ischemic heart disease and coronary and systemic vascular hemodynamic mechanisms underlying the disease. He is principal investigator for the UF center for the NHLBI-funded Women's Ischemia Syndrome Evaluation (WISE) and the UF center for the Cardiovascular Cell Therapy Research Network (CCTRN). He has been or is the PI for many investigator initiated clinical trials, as well as NHLBI trials. He is past president of the American College of Cardiology (ACC), the national professional organization for cardiovascular specialists. He currently serves on the Board of Trustees of the ACC and many committees and task forces and is the founder and overall Project Chair for the Vascular Biology Working Group (VBWG).