Clinical trials

Investigator

Adolfo Ramirez-Zamora

This is a single-center, open-label study designed to evaluate the feasibility, safety, and preliminary efficacy of cerebellar adaptive deep brain stimulation (aDBS) in adults with spinocerebellar ataxia type 6 (SCA6). A total of 5 participants will…

Ages

21 Years - 89 Years

Sexes

All

Investigator

Carmen Leon Astudillo

Spinocerebellar ataxias (SCA) are genetic neurological diseases that cause imbalance, poor coordination, and speech difficulties. There are different kinds of SCA and this study will focus on types 1, 2,3, and 6 (SCA 1, SCA 2, SCA 3 , also known as…

Investigators

Sub Subramony, Matthew R Burns

Ages

6 Years - N/A

Sexes

All

This is a natural history study prospectively investigating neuroimaging markers of disease progression in children and adults with Friedreich ataxia (FA). There will be three assessment periods (baseline, 12 and 24 months). The study will include…

Ages

5 Years - N/A

Sexes

All

Study ROR-PH-303, ADVANCE EXTENSION, is an open-label extension (OLE) study for participants with WHO Group 1 PAH who have participated in another Phase 2 or Phase 3 study of ralinepag.

Investigator

Ali Ataya

Ages

18 Years - N/A

Sexes

All

Investigator

Ali Ataya

Investigator

Ali Ataya

This open-label extension study will evaluate the long-term safety, tolerability and efficacy of orally inhaled seralutinib in subjects who have completed a previous seralutinib study

Investigator

Ali Ataya

Ages

18 Years - 75 Years

Sexes

All