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Hyperplasia

Definition

Hyperplasia is increased cell production in a normal tissue or organ. Hyperplasia may be a sign of abnormal or precancerous changes. This is called pathologic hyperplasia.

It can also be due to the growth of normal cells. This is called physiologic hyperplasia.

Alternative Names

Hypergenesis

Gallery

Hyperplasia
Hyperplasia is the increased cell production of normal tissue in the body which causes the organ to increase in size.

References

Oakes SA. Cell injury, cell death, and adaptations. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 10th ed. Philadelphia, PA: Elsevier; 2021:chap 2.

Last reviewed July 3, 2025 by Robert Hurd, MD, Professor of Endocrinology and Health Care Ethics, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

Related specialties

Clinical trials: Hyperplasia

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News and patient stories: Hyperplasia

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