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  • Determine effectiveness of Anifrolumab In SYstemic sclerosis (DAISY)

    The purpose of this study is to evaluate the efficacy and safety of treatment with subcutaneous anifrolumab versus placebo in adult participants with systemic sclerosis. The target population for this study includes patients who meet the 2013…

    Investigator
    Michael R Bubb
    Ages
    18 Years - 70 Years
    Sexes
    All
  • JIVE (LARIMAR)

    To evaluate the safety and tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of subcutaneous (SC) administration of CTI-1601 over 28 days in subjects with Friedreich's ataxia (FRDA).

    Investigator
    Sub Subramony
    Ages
    18 Years - N/A
    Sexes
    All
  • APL2-C3G-310

    This is a Phase 3 study to assess the efficacy and safety of twice-weekly subcutaneous (SC) doses of pegcetacoplan compared to placebo in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative glomerulonephritis (IC-MPGN) on…

    Investigator
    Lawrence R Shoemaker
    Ages
    12 Years - N/A
    Sexes
    All
  • REPLENISH

    The purpose of this study is to demonstrate the efficacy and safety of secukinumab 300 milligram (mg) and 150 mg administered subcutaneously (s.c.) for 52 weeks in combination with prednisone tapered over 24 weeks in adult participants with PMR who…

    Investigator
    Roland Staud
    Ages
    50 Years - 100 Years
    Sexes
    All