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Definition

Substance use is the continued use of alcohol, illegal drugs, or the misuse of prescription or over-the-counter medicines with negative consequences. These consequences may involve:

  • Problems at work, school, home or in interpersonal relationships
  • Problems with the law
  • Health problems
  • Physical risks that come with using drugs in dangerous situations

Substances that are commonly used include:

Alternative Names

Substance abuse; Illicit drug abuse; Narcotic abuse; Hallucinogen abuse

References

American Psychiatric Association. Substance-related and addictive disorders. In: American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 5th ed, text revision. Arlington, VA: American Psychiatric Publishing; 2022.

Weiss RD, Liebschutz JM. Drug use disorders. In: Goldman L, Cooney KA, eds. Goldman-Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 365.

Last reviewed July 17, 2024 by Fred K. Berger, MD, addiction and forensic psychiatrist, Scripps Memorial Hospital, La Jolla, CA. Internal review and update on 07/01/2025 by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

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Calendar events and lectures: Substance Use

UF Health Florida Recovery Center's 7th Annual Run 4 Recovery 5K
Depot Park
Gainesville, FL 32601

Come join us Saturday, September 19th, at Depot Park, as we aim to increase awareness of substance use disorders and celebrate those in recovery!…

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News and patient stories: Substance Use

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