Clinical trials

Investigator

Carl J Pepine

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Investigator

Michael R Bubb

Ages

18 Years - 65 Years

Sexes

All

The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of moderate to severe disease activity.

Investigator

Michael R Bubb

Ages

16 Years - N/A

Sexes

All

HQ-HTN-G01 is a prospective, multicenter, single arm, open label, early feasibility study to evaluate initial safety and device design concept of "HyperQureTM RDN System", laparoscopic renal denervation therapy, in patients with resistant…

Investigator

Mark S Segal

Ages

22 Years - 80 Years

Sexes

All

The goal of this clinical trial is to learn if the Arcevo LSA stent graft can safely and effectively treat patients that have an acute or chronic aortic dissection and/or aneurysm that involves the aortic arch and the descending thoracic aorta, with…

Investigator

Eric I Jeng

Ages

18 Years - 80 Years

Sexes

All

To find out the effect of Lu AF82422 on disease progression in participants with multiple system atrophy.

Investigator

Nikolaus McFarland

Ages

40 Years - 75 Years

Sexes

All

The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve System to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main…

Investigator

Brandon R Allen

Ages

22 Years - N/A

Sexes

All

The investigators will implant and monitor 8 research subjects with a subcortical closed-loop system for detection and suppression of tics in subjects with medically refractory debilitating Tourette Syndrome. The project will use the FDA-approved…

Investigator

Michael S Okun

Ages

18 Years - 85 Years

Sexes

All

The purpose of this study is to evaluate initial clinical safety, device functionality and effectiveness of the Edwards Transcatheter Atrial Shunt System.

Investigator

Dominick J Angiolillo

Ages

18 Years - N/A

Sexes

All

The primary objective of this Pivotal study is to demonstrate the safety and effectiveness of the Pulse Biosciences nsPFA™ Cardiac Surgery System in treating atrial fibrillation during concomitant cardiac surgical procedures.

Investigator

Thomas M Beaver

Ages

18 Years - 85 Years

Sexes

All