Clinical trials
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Exercise testing in DMD -
Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine Tumors This phase II trial studies the effect of capecitabine and temozolomide after surgery in treating patients with high-risk well-differentiated pancreatic neuroendocrine tumors. Chemotherapy drugs, such as capecitabine and temozolomide, work in…
- Investigator
- Brian H Ramnaraign
- Ages
- 18 Years - N/A
- Sexes
- All
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Testing the Combination of ZEN-3694 and Talazoparib in Ps w/ Advanced Solid Tumors; ComBET This phase II trial tests whether ZEN003694 (ZEN-3694) in combination with talazoparib works to shrink tumors in patients with solid tumors that are unlikely to be cured or controlled with treatment and that may have spread from where it first…
- Investigator
- Merry J Markham
- Ages
- 18 Years - N/A
- Sexes
- All
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Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy for Limited mCRC(ERASur) This phase III trial compares total ablative therapy and usual systemic therapy to usual systemic therapy alone in treating patients with colorectal cancer that has spread to up to 4 body sites (limited metastatic). The usual approach for patients…
- Investigator
- Kathryn E Hitchcock
- Ages
- 18 Years - N/A
- Sexes
- All
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NRG-BR009: Testing the addition of chemo to SOC in breast cancer patients at high risk of recurrence This Phase III Trial will determine whether adjuvant chemotherapy (ACT) added to ovarian function suppression (OFS) plus endocrine therapy (ET) is superior to OFS plus ET in improving invasive breast cancer-free survival (IBCFS) among premenopausal,…
- Investigator
- Karen Daily
- Ages
- 18 Years - 60 Years
- Sexes
- Female
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A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment o This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after…
- Investigator
- William Slayton
- Ages
- N/A - 22 Years
- Sexes
- All
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Study to test whether BI 456906 helps people living with overweight or obesity without diabetes 2 This study is open to adults who are at least 18 years old and have a body mass index (BMI) of 30 kg/m² or more, or a BMI of 27 kg/m² or more and at least one health problem related to their weight. People with type 2 diabetes cannot take part…
- Investigator
- Kenneth Cusi
- Ages
- 18 Years - N/A
- Sexes
- All
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Testing Triapine w/ Targeted Radiation-based LU177 vs Lu177 alone in pts w/ metastatic NETs This phase II trial compares the effect of adding triapine to lutetium Lu 177 dotatate versus lutetium Lu 177 dotatate alone (standard therapy) in shrinking tumors or slowing tumor growth in patients with neuroendocrine tumors that have spread from…
- Investigator
- Kathryn E Hitchcock
- Ages
- 18 Years - N/A
- Sexes
- All
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TAPUR: Testing FDA Approved Drugs That Target Specific Abnormal Tumor Genes in Pts w/Advanced Cancer The purpose of the study is to learn from the real world practice of prescribing targeted therapies to patients with advanced cancer whose tumor harbors a genomic variant known to be a drug target or to predict sensitivity to a drug. Note: Due to…
- Investigator
- Thomas J George
- Ages
- 12 Years - N/A
- Sexes
- All
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Study to Test Whether BI 456906 Helps People Living With Overweight/Obesity Who Have Diabetes 2 This study is open to adults who are at least 18 years old and have a body mass index of 27 kg/m² or more. People can take part if they have type 2 diabetes and if they are currently being treated only with diet and exercise or with specific…
- Investigator
- Kenneth Cusi
- Ages
- 18 Years - N/A
- Sexes
- All