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Ashley Ghiaseddin, MD : Research

Neuro-Oncologist (Brain Cancer Specialist)

Photo of Ashley Ghiaseddin

Research at a glance

Top areas of exploration

  • Brain Neoplasms , 13 publications
  • Glioblastoma , 7 publications
  • Tumor Microenvironment , 3 publications
  • Immunotherapy , 3 publications

Research activity

33 publications

284 citations

Why is this important?

Active clinical trials

OPTIMUS PRIME - Laser Ablation Surgery and Pembrolizumab for Recurrent GlIoblastoMa

In this study we are evaluating the safety and feasibility of the triple combination (TTFields, MLA, pembrolizumab) in adult patients diagnosed with recurrent or progressive glioblastoma (GBM) WHO Grade IV, IDH wild type or recurrent or progressive…

Investigator
Ashley Ghiaseddin
Status
Accepting Candidates
Ages
18 Years - 90 Years
Sexes
All
EF-41/ KEYNOTE D58

This is a multicenter, two-arm, randomized, double-blind, placebo-controlled study of Optune® (Tumor Treating Fields at 200 kHz) together with maintenance Temozolomide (TMZ) chemotherapy agent and pembrolizumab compared to Optune® together with…

Investigator
Ashley Ghiaseddin
Status
Accepting Candidates
Ages
18 Years - N/A
Sexes
All

My publications

33 publications

2025

Systemic mRNA aggregates elicit immunologic reprogramming that unlocks anti-cancer immunity.

Human vaccines & immunotherapeutics

PubMed Publisher's site

2025

A Rare Presentation of Adult Primary Leptomeningeal Medulloblastoma: Case Report.

Case reports in pathology

PubMed Publisher's site

2025

Efficacy and safety of adjuvant TTFields plus pembrolizumab and temozolomide in newly diagnosed glioblastoma: A phase 2 study.

Med (New York, N.Y.)

PubMed Publisher's site

2025

Targeting immune checkpoint LAIR1 with antibody blockade or 3-in-1 CAR T cells enhances antitumor response

Journal of Clinical Investigation

Publisher's site

2025

How do I prescribe and manage mIDH inhibitors in patients with IDH-mutant glioma?

Neuro-oncology practice

PubMed Publisher's site