2026
Prader-Willi Syndrome
GeneReviews
Research at a glance
Top areas of exploration
- Prader-Willi Syndrome , 66 publications
- Chromosomes, Human, Pair 15 , 32 publications
- Angelman Syndrome , 27 publications
- Genomic Imprinting , 22 publications
Research activity
Focus
The overarching goal of Dr. Driscoll’s research is to blend meaningful discoveries at the laboratory bench and the patient’s bedside which ultimately will result in significant beneficial treatments for both children and adults. His research interests are focused in three interrelated areas that combine his clinical and basic science expertise; Genomic imprinting/Epigenetics; Prader-Willi syndrome; and early-onset major obesity (EMO).
Prader-Willi syndrome (PWS) is the most frequently diagnosed genetic cause of obesity and it is the result of a derangement in genomic imprinting. Our lab is using PWS as a model system to better understand both childhood obesity and the phenomenon of genomic imprinting.
My publications
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124 publications
2023
Hyperinsulinemia is a probable trigger for weight gain and hyperphagia in individuals with Prader‐Willi syndrome
Obesity Science & Practice
Publisher's site2022
Critical review of bariatric surgical outcomes in patients with Prader-Willi syndrome and other hyperphagic disorders.
Obesity (Silver Spring, Md.)
PubMed • Publisher's site2022
Molecular Classes and Growth Hormone Treatment Effects on Behavior and Emotion in Patients with Prader–Willi Syndrome
Journal of Clinical Medicine
Publisher's site2022
The presentation, course and outcome of COVID-19 infection in people with Prader-Willi syndrome: unexpected findings from an international survey.
Orphanet journal of rare diseases
PubMed • Publisher's site