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Irving D Weiner, MD : Research

Nephrologist (Kidney Specialist)

Photo of Irving D Weiner

Research at a glance

Top areas of exploration

  • Kidney , 26 publications
  • Ammonia , 26 publications
  • Kidney Tubules, Collecting , 24 publications
  • Membrane Glycoproteins , 18 publications

Research activity

83 publications

2,564 citations

Why is this important?

Focus

Dr. Weiner's pre-clinical research interests focus on the molecular mechanisms and the regulation of acid-base hemostasis. This includes studies on ammonia metabolism, including regulation of production and novel mechanisms of transport by specific proteins. Dr. Weiner's laboratory played a major role in a recognition the Rhesus glycoproteins enable regulated transport of ammonia gas, NH3, which resulted in a paradigm shift shift in the understanding of ammonia metabolism.

My publications

83 publications

2024

Angiotensin II acts through Rac1 to upregulate pendrin: role of NADPH oxidase

American Journal of Physiology-Renal Physiology

Publisher's site

2023

A Novel Form of Renal Tubular Acidosis Associated With Immune Checkpoint Inhibitors.

Kidney international reports

PubMed Publisher's site

2023

Rechallenge in Immune Checkpoint Inhibitors Associated Renal Tubular Acidosis.

Kidney international reports

PubMed Publisher's site

2023

The proximal tubule through an NBCe1-dependent mechanism regulates collecting duct phenotypic and remodeling responses to acidosis

American Journal of Physiology-Renal Physiology

PubMed Publisher's site

2022

Acid-base effects of combined renal deletion of NBCe1-A and NBCe1-B

American Journal of Physiology-Renal Physiology

PubMed Publisher's site