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James Wymer, MD, FAAN : Research

Neuromuscular Medicine Specialist

Rated 4.8 out of 5 stars
Photo of James Wymer

Research at a glance

Top areas of exploration

  • Amyotrophic Lateral Sclerosis , 34 publications
  • Deglutition Disorders , 11 publications
  • Deglutition , 10 publications
  • Disease Progression , 8 publications

Research activity

67 publications

2,024 citations

Why is this important?

Active clinical trials

COYA

The ALSTARS trial will be conducted across 20-25 sites in the US and Canada, and will evaluate the safety and efficacy of an investigational treatment called COYA 302 for adults with Amyotrophic Lateral Sclerosis (ALS). COYA 302 is an…

Investigator
James Wymer
Status
Accepting Candidates
Ages
18 Years - 80 Years
Sexes
All
LUMINA

This study is a placebo-controlled Phase I study to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of the antisense oligonucleotide (ASO) AMX0114 in adult participants with amyotrophic lateral sclerosis (ALS).

Investigator
James Wymer
Status
Accepting Candidates
Ages
18 Years - N/A
Sexes
All
ALS Imaging
Investigator
James Wymer
Status
Accepting Candidates

My publications

67 publications

2026

Prospective Validation of the New PLS Diagnostic Criteria From PLS Natural History Study: EMG and Neurofilament Analyses.

Muscle & nerve

PubMed Publisher's site

2026

Diagnostic differences between military veterans and non-veterans: data from the United States National ALS Registry.

Amyotrophic lateral sclerosis & frontotemporal degeneration

PubMed Publisher's site

2026

Author Correction: Leveraging deep single-soma RNA sequencing to explore the neural basis of human somatosensation.

Nature neuroscience

PubMed Publisher's site

2026

Head trauma and environment progression of amyotrophic lateral sclerosis: long-term data from the National ALS Registry.

BMJ neurology open

PubMed Publisher's site

2026

Primary Lateral Sclerosis Natural History Study: Primary Lateral Sclerosis Functional Rating Scale and Other Outcomes Assessment.

Annals of neurology

PubMed Publisher's site