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John A Ligon, MD : Research

Pediatric Hematologist/Oncologist (Child Cancer Specialist)

Photo of John A Ligon

Research at a glance

Top areas of exploration

  • Neoplasms , 5 publications
  • Tumor Microenvironment , 3 publications
  • Immunotherapy , 3 publications
  • RNA, Messenger , 2 publications

Research activity

43 publications

95 citations

Why is this important?

Active clinical trials

OMS721-HCT-002

The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).

Investigator
John A Ligon
Status
Accepting Candidates
Ages
28 Days - 17 Years
Sexes
All

My publications

43 publications

2025

Systemic mRNA aggregates elicit immunologic reprogramming that unlocks anti-cancer immunity.

Human vaccines & immunotherapeutics

PubMed Publisher's site

2025

Role of race and ethnicity in survival among children/young adults with relapsed ALL: a Children’s Oncology Group report

Blood Advances

Publisher's site

2025

Systemic mRNA vaccines elicit rapid immune activation in canine brain tumors

Journal for ImmunoTherapy of Cancer

Publisher's site

2025

Gene-edited CAR T cells: going the distance in B-ALL

Blood Advances

Publisher's site

2025

Sensitization of tumours to immunotherapy by boosting early type-I interferon responses enables epitope spreading

Nature Biomedical Engineering

Publisher's site