Phase 2 study to compare INBRX-101 to plasma derived A1PI therapy in adults with AATD emphysema
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 18 Years - 80 Years
- Sexes
- All
Research at a glance
Top areas of exploration
- alpha 1-Antitrypsin Deficiency , 9 publications
- Pulmonary Disease, Chronic Obstructive , 8 publications
- alpha 1-Antitrypsin , 7 publications
- Phenotype , 3 publications
Research activity
Active clinical trials
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
The purpose of this study is to evaluate the safety and tolerability of 72 milligrams per kilogram (mg/kg) and 180 mg/kg Alpha-1 15%, administered as a single-dose subcutaneous (SC) infusion and subsequently as weekly SC infusions over 8 weeks in…
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 18 Years - 80 Years
- Sexes
- All
My publications
Filter publications
41 publications
2023
Lung microhaemorrhage drives oxidative/inflammatory damage in α1-antitrypsin deficiency.
ERJ open research
PubMed • Publisher's site2023
Testing Patterns and Disparities for Alpha-1 Antitrypsin Deficiency.
The American journal of medicine
PubMed • Publisher's site2023
Therapeutic drug monitoring in cystic fibrosis and associations with pulmonary exacerbations and lung function
Respiratory Medicine
Publisher's site2022
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Respiratory research
PubMed • Publisher's site2022
Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.
PloS one
PubMed • Publisher's site