Phase 2 study to compare INBRX-101 to plasma derived A1PI therapy in adults with AATD emphysema
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 18 Years - 80 Years
- Sexes
- All
Research at a glance
Top areas of exploration
- alpha 1-Antitrypsin Deficiency , 9 publications
- Pulmonary Disease, Chronic Obstructive , 8 publications
- alpha 1-Antitrypsin , 7 publications
- Phenotype , 3 publications
Research activity
Active clinical trials
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
The purpose of this study is to evaluate the safety and tolerability of 72 milligrams per kilogram (mg/kg) and 180 mg/kg Alpha-1 15%, administered as a single-dose subcutaneous (SC) infusion and subsequently as weekly SC infusions over 8 weeks in…
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 18 Years - 80 Years
- Sexes
- All
My publications
Filter publications
41 publications
2023
Augmentation Therapy Modulates Systemic Inflammation in Individuals with Alpha-1 Antitrypsin Deficiency and Chronic Obstructive Pulmonary Disease.
Chronic obstructive pulmonary diseases (Miami, Fla.)
PubMed • Publisher's site2023
Development of a risk score to increase detection of severe alpha-1 antitrypsin deficiency.
ERJ open research
PubMed • Publisher's site2023
Impact of a Computerized Clinical Decision Support System to Improve Chronic Obstructive Pulmonary Disease Diagnosis and Testing for Alpha-1 Antitrypsin Deficiency.
Annals of the American Thoracic Society
PubMed • Publisher's site2023
Inhaled mRNA therapy for treatment of cystic fibrosis: Interim results of a randomized, double-blind, placebo-controlled phase 1/2 clinical study.
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society
PubMed • Publisher's site2023
Lung Inflammation in alpha-1-antitrypsin deficient individuals with normal lung function.
Respiratory research
PubMed • Publisher's site