- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
Research at a glance
Top areas of exploration
- alpha 1-Antitrypsin Deficiency , 10 publications
- Pulmonary Disease, Chronic Obstructive , 9 publications
- alpha 1-Antitrypsin , 7 publications
- Cystic Fibrosis , 4 publications
Research activity
Active clinical trials
The REACH study is for people with CF who do not take cystic fibrosis transmembrane conductance regulator (CFTR) modulators. The goal of the REACH study is to collect research data, including health data and specimens, from people with CF who do not…
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 12 Years - N/A
- Sexes
- All
The Sponsor is developing KB408, a replication-defective, non-integrating herpes simplex virus type 1 (HSV-1)-derived vector engineered to deliver functional full-length human SERPINA1 to the airways of people with alpha-1 antitrypsin deficiency…
- Investigator
- Jorge E Lascano
- Status
- Accepting Candidates
- Ages
- 18 Years - 70 Years
- Sexes
- All
My publications
Filter publications
46 publications
2026
Epidemiology of Alpha-1 Antitrypsin Deficiency in the Veterans Health Administration.
Annals of the American Thoracic Society
PubMed • Publisher's site2026
Cardiovascular disease-associated admissions in patients with Cystic Fibrosis: A 7-Year U.S. National Inpatient Sample Analysis.
Heart & lung : the journal of critical care
PubMed • Publisher's site2025
Inhaled alpha-1 antitrypsin (AAT) restores lower respiratory tract protease-antiprotease homoeostasis and reduces inflammation in AAT-deficient individuals: a randomised phase 2 study.
ERJ open research
PubMed • Publisher's site2024
Liver Characterization of a Cohort of Alpha-1 Antitrypsin Deficiency Patients with and without Lung Disease.
Journal of clinical and translational hepatology
PubMed • Publisher's site2024
Recombinant Alpha-1 Antitrypsin-Fc Fusion Protein INBRX-101 in Adults With Alpha-1 Antitrypsin Deficiency: A Phase 1 Study.
Chronic obstructive pulmonary diseases (Miami, Fla.)
PubMed • Publisher's site