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Kenneth Cusi, MD, FACP, FACE : Research

Endocrinologist (Diabetes & Hormones Specialist)

Additional languages:
Spanish
Photo of Kenneth Cusi

Research at a glance

Top areas of exploration

  • Non-alcoholic Fatty Liver Disease , 90 publications
  • Diabetes Mellitus, Type 2 , 76 publications
  • Liver , 50 publications
  • Insulin Resistance , 48 publications

Research activity

218 publications

23,611 citations

Why is this important?

Focus

Dr. Cusi is the principal investigator of a number of ongoing clinical research projects. His grants focus on cutting-edge research in adult endocrinology, diabetes and metabolism, both on clinical and basic research aspects related to the role of obesity and lipotoxicity in the development of Type 2 diabetes and its complications, in particular, the pathogenesis of NAFLD.  He has published more than 90 original articles, invited reviews and book chapters in the main journals in the fields of obesity, diabetes and liver disease.  Dr. Cusi is a nationally and internationally recognized investigator and speaker on the impact of NAFLD in humans,. His observation in 2006 (NEJM, 2006) that pioglitazone is an effective pharmacological treatment for NASH in people with prediabetes or T2D, confirmed in a 3-year study (Annals Intern Med, 2016), has been incorporated into all major NAFLD guidelines for the management of NAFLD. His current work centers on discovering underlying mechanisms of NAFLD and new treatments. He is an advocate for liver screening in type 2 diabetes and other groups at high-risk groups of cirrhosis from NASH. Most recently involved in the multidisciplinary 2021 AGA consensus statement, 2021 ALEH NAFLD guidance, 2022 AACE NAFLD clinical practice guideline, and 2023 ADA Standards of Care related to NAFLD.

Active clinical trials

NIH AIM 2 - Low Dose Pioglitazone in NASH

To determine the safety and efficacy of low-dose pioglitazone (15 mg per day) on liver histology in in patients with T2DM with biopsy-proven nonalcoholic steatohepatitis (NASH).

Investigator
Kenneth Cusi
Status
Accepting Candidates
Ages
21 Years - 75 Years
Sexes
All

My publications

218 publications

2024

A global action agenda for turning the tide on fatty liver disease

Hepatology

Publisher's site

2024

A multisociety Delphi consensus statement on new fatty liver disease nomenclature.

Annals of hepatology

PubMed Publisher's site

2024

Artificial intelligence-assisted digital pathology for non-alcoholic steatohepatitis: current status and future directions.

Journal of hepatology

PubMed Publisher's site

2024

From NAFLD to MASLD: Promise and pitfalls of a new definition†

Hepatology

Publisher's site

2024

Global survey of stigma among physicians and patients with nonalcoholic fatty liver disease

Journal of Hepatology

Publisher's site