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Lawrence R Shoemaker, MD

Pediatrician (Kids / Children Specialist)

Additional languages:
French
Photo of Lawrence R Shoemaker

Research at a glance

Top areas of exploration

  • Calcium , 6 publications
  • Bartter Syndrome , 5 publications
  • Immunosuppressive Agents , 4 publications
  • Heart Transplantation , 4 publications

Research activity

34 publications

561 citations

Why is this important?

Focus

Active clinical trials

APL2-C3G-314

This study is designed as a long-term extension to Study APL2-C3G-310, and is being conducted to establish the long-term safety and efficacy of pegcetacoplan in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative…

Investigator
Lawrence R Shoemaker
Status
Accepting Candidates
Ages
12 Years - N/A
Sexes
All
APL2-C3G-310

This is a Phase 3 study to assess the efficacy and safety of twice-weekly subcutaneous (SC) doses of pegcetacoplan compared to placebo in patients with C3 glomerulopathy (C3G) or immune-complex membranoproliferative glomerulonephritis (IC-MPGN) on…

Investigator
Lawrence R Shoemaker
Status
Accepting Candidates
Ages
12 Years - N/A
Sexes
All

My publications

34 publications

2024

Dysregulation of kidney proteases in the pathogenesis of hypertension following unilateral nephrectomy in juvenile mice.

American journal of translational research

PubMed

2024

Functional and metabolomic analysis of urinary extracellular vesicles from juvenile mice with renal compensatory hypertrophy.

Biochimica et biophysica acta. Molecular basis of disease

PubMed Publisher's site

2024

Thrombotic microangiopathy following systemic AAV administration is dependent on anti-capsid antibodies.

The Journal of clinical investigation

PubMed Publisher's site

2023

Does kidney biopsy in pediatric lupus patients "complement" the management and outcomes of silent lupus nephritis? Lessons learned from a pediatric cohort.

Pediatric nephrology (Berlin, Germany)

PubMed Publisher's site

2022

Extracellular vesicles from focal segmental glomerulosclerosis pediatric patients induce STAT3 activation and mesangial cell proliferation.

PloS one

PubMed Publisher's site