- Investigator
- Malú Gámez Tansey
- Status
- Accepting Candidates
Research at a glance
Top areas of exploration
- Inflammation , 10 publications
- Parkinson Disease , 10 publications
- Microglia , 9 publications
- Tumor Necrosis Factor-alpha , 7 publications
Research activity
Focus
The research interests of our laboratory include investigating the role and regulation of immune and inflammatory mechanisms that protect against or predispose and individual to develop neurodegenerative disorders. Genetic and environmental contributions to lysosomal dysfunction and alterations in lipid signaling that dysregulate neuroimmune activity and trigger neuroinflammation are a main focus of investigation; as is the role of the gut-brain axis and chronic peripheral inflammation in the pathogenesis and progression of neurodegeneration.
Active clinical trials
My publications
Filter publications
78 publications
2024
Calcium influx into astrocytes plays a pivotal role in inflammation-driven behaviors
Cell Calcium
Publisher's site2023
APOE and immunity: Research highlights
Alzheimer's & Dementia
Publisher's site2023
ASO-mediated knockdown or kinase inhibition of G2019S-Lrrk2 modulates lysosomal tubule-associated antigen presentation in macrophages
Molecular Therapy - Nucleic Acids
PubMed • Publisher's site2023
Central and peripheral innate and adaptive immunity in Parkinson’s disease
Science Translational Medicine
Publisher's site2023
Editorial: Glial-targeted therapeutics for CNS disease: getting there from here
Frontiers in Cellular Neuroscience
PubMed • Publisher's site