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Melissa E Elder, MD, PhD

Immunologist, Pediatric Rheumatologist (Child Joint Disease Specialist)

Photo of Melissa E Elder

Research at a glance

Top areas of exploration

  • T-Lymphocytes , 7 publications
  • Severe Combined Immunodeficiency , 7 publications
  • Autoantibodies , 6 publications
  • Protein-Tyrosine Kinases , 5 publications

Research activity

47 publications

1,930 citations

Why is this important?

Active clinical trials

NI-0501-14; Gamifant

The purpose of this study is to assess the safety, tolerability and efficacy of emapalumab in children and adults with macrophage activation syndrome (sHLH/MAS) in Still's disease (including systemic juvenile idiopathic arthritis and adult onset…

Investigator
Melissa E Elder
Status
Accepting Candidates
Ages
6 Months - 80 Years
Sexes
All
USIDNet
Investigator
Melissa E Elder
Status
Accepting Candidates

My publications

47 publications

2024

Thrombotic microangiopathy following systemic AAV administration is dependent on anti-capsid antibodies.

The Journal of clinical investigation

PubMed Publisher's site

2023

Adeno-associated virus-mediated gene therapy in a patient with Canavan disease using dual routes of administration and immune modulation.

Molecular therapy. Methods & clinical development

PubMed Publisher's site

2023

Bortezomib is efficacious in the treatment of severe childhood-onset neuropsychiatric systemic lupus erythematosus with psychosis: a case series and mini-review of B-cell immunomodulation in antibody-mediated diseases.

Clinical rheumatology

PubMed Publisher's site

2023

Case Report: Refractory macrophage activation syndrome requiring high-dose anakinra, emapalumab, and etoposide therapy in early-onset systemic juvenile idiopathic arthritis associated with adenoviremia.

Frontiers in pediatrics

PubMed Publisher's site

2023

Race, ethnicity and patient-reported outcomes in childhood-onset systemic lupus erythematosus.

Clinical and experimental rheumatology

PubMed Publisher's site