FABULINUS
This is a randomized, parallel group, double-blind Phase 2 study with a 52-week blinded extension evaluating the safety and efficacy of 3 dose levels of frexalimab in comparison with placebo in participants with newly diagnosed T1D on insulin…
- Investigator
- Michael J Haller
- Status
- Accepting Candidates
- Ages
- 12 Years - 35 Years
- Sexes
- All
TN-31 JAKPOT T1D
A multi-center, placebo-controlled, double blind, 1:1:1 randomized control clinical trial testing two different JAK Inhibitors abrocitnib, ritlecitinib, and placebo in subjects with recent onset Stage 3 Type 1 Diabetes within 100 days of diagnosis.
- Investigators
- Laura Jacobsen, Michael J Haller
- Status
- Accepting Candidates
- Ages
- 12 Years - 35 Years
- Sexes
- All
Protocol TN-25
The study is a two-arm, multicenter, double-blinded clinical trial testing sequential therapy with rituximab-pvvr followed by abatacept versus rituximab-pvvr alone in new onset T1D. The primary objective is to test whether the C-peptide response to…
- Investigators
- Laura Jacobsen, Michael J Haller
- Status
- Accepting Candidates
- Ages
- 8 Years - 45 Years
- Sexes
- All