2023
ATM, KAP1 and the Epstein–Barr virus polymerase processivity factor direct traffic at the intersection of transcription and replication
Nucleic Acids Research
PubMed • Publisher's siteResearch at a glance
Top areas of exploration
- B-Lymphocytes , 11 publications
- Cell Line, Tumor , 9 publications
- Virus Activation , 9 publications
- STAT3 Transcription Factor , 8 publications
Research activity
Focus
We study Epstein-Barr virus (EBV), the first human cancer-causing virus to be discovered. EBV causes infectious mononucleosis and is causal or linked to several B lymphocyte- and epithelial cell-cancers. Some of our experiments are designed to explore how EBV disturbs and exploits cellular physiology to drive unscheduled cell proliferation, a central feature of cancer. Other experiments are directed at understanding how this virus persists successfully in over 95% of humans. Both lines of investigation have revealed several targets for anti-cancer and anti-viral intervention.
My publications
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50 publications
2023
Beta human papillomavirus 8E6 promotes alternative end joining.
eLife
PubMed • Publisher's site2023
Inflammation and Epstein–Barr Virus at the Crossroads of Multiple Sclerosis and Post-Acute Sequelae of COVID-19 Infection
Viruses
PubMed • Publisher's site2023
Is Kawasaki Disease Caused by a Respiratory Virus?
The Pediatric infectious disease journal
PubMed • Publisher's site2023
Virology under the Microscope—a Call for Rational Discourse
mSphere
PubMed • Publisher's site