Michael Haller, M.D.

Michael J Haller, M.D.

(352) 265-7337

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Publications

The Neighborhood Deprivation Index and Provider Geocoding Identify Critical Catchment Areas for Diabetes Outreach
Journal of Clinical Endocrinology & Metabolism
2020

Slowed Metabolic Decline After 1 Year of Oral Insulin Treatment Among Individuals at High Risk for Type 1 Diabetes in the Diabetes Prevention Trial-Type 1 (DPT-1) and TrialNet Oral Insulin Prevention Trials
Diabetes
2020

Innate inflammation drives NK cell activation to impair Treg activity
Journal of Autoimmunity
2020

Human Regulatory T Cells From Umbilical Cord Blood Display Increased Repertoire Diversity and Lineage Stability Relative to Adult Peripheral Blood
Frontiers in Immunology
2020

Factors Associated with Decline of C-peptide in a Cohort of Young Children Diagnosed with Type 1 Diabetes
Journal of Clinical Endocrinology & Metabolism
2020

Comparing Beta Cell Preservation Across Clinical Trials in Recent-Onset Type 1 Diabetes
Diabetes Technology & Therapeutics
2020

Commercially Available Insulin Products Demonstrate Stability Throughout the Cold Supply Chain Across the United States
Diabetes Care
2020

Clinical trial data validate the C-peptide estimate model in type 1 diabetes
Diabetologia
2020

The association between stressful life events and respiratory infections during the first 4 years of life: The Environmental Determinants of Diabetes in the Young study
Stress and Health
2019

Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children
Pediatric Diabetes
2019

Metabolite-related dietary patterns and the development of islet autoimmunity
Scientific Reports
2019

Low-Dose Anti-Thymocyte Globulin Preserves C-Peptide, Reduces HbA(1c), and Increases Regulatory to Conventional T-Cell Ratios in New-Onset Type 1 Diabetes: Two-Year Clinical Trial Data
Diabetes
2019

Estimated Lifetime Economic Burden of Type 1 Diabetes
Diabetes Technology & Therapeutics
2019

Early Probiotic Supplementation and the Risk of Celiac Disease in Children at Genetic Risk
Nutrients
2019

Biologic and social factors predict incident kidney disease in type 1 diabetes: Results from the T1D exchange clinic network
Journal of Diabetes and Its Complications
2019

Association of Gluten Intake During the First 5 Years of Life With Incidence of Celiac Disease Autoimmunity and Celiac Disease Among Children at Increased Risk
Jama-Journal of the American Medical Association
2019

Pandemrix (R) Vaccination Is Not Associated With Increased Risk of Islet Autoimmunity or Type 1 Diabetes in the Teddy Study Children
Diabetologia
2018

Objectively Measured Adherence in Adolescents With Type 1 Diabetes on Multiple Daily Injections and Insulin Pump Therapy.
Journal of Pediatric Psychology
2018

Low-Dose Anti-Thymocyte Globulin (Atg) Preserves -Cell Function and Improves Hba(1C) in New-Onset Type 1 Diabetes
Diabetes Care
2018

Ispad Clinical Practice Consensus Guidelines 2018: Stages of Type 1 Diabetes in Children and Adolescents
Pediatric Diabetes
2018

Immune Mechanisms and Pathways Targeted in Type 1 Diabetes.
Current Diabetes Reports
2018

Gestational respiratory infections interacting with offspring HLA and CTLA-4 modifies incident beta-cell autoantibodies
Journal of Autoimmunity
2018

Family Adjustment to Diabetes Diagnosis in Children: Can Participation in a Study on Type 1 Diabetes Genetic Risk Be Helpful?
Pediatric diabetes
2018

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls
Pediatric Diabetes
2017

Rebranding Asymptomatic Type 1 Diabetes: the Case for Autoimmune Beta Cell Disorder As a Pathological and Diagnostic Entity
Diabetologia
2017

Lactobacillus Johnsonii N6.2 Modulates the Host Immune Responses: a Double-Blind, Randomized Trial in Healthy Adults
Frontiers in Immunology
2017

Expansion of Human Tregs From Cryopreserved Umbilical Cord Blood for Gmp-Compliant Autologous Adoptive Cell Transfer Therapy
Molecular therapy. Methods & clinical development
2017

Analgesic Antipyretic Use Among Young Children in the Teddy Study: No Association With Islet Autoimmunity
Bmc Pediatrics
2017

Updates on Immune Therapies in Type 1 Diabetes.
European endocrinology
2016

The Influence of Type 1 Diabetes on Pancreatic Weight
Diabetologia
2016

Mobilization Without Immune Depletion Fails to Restore Immunological Tolerance or Preserve Beta Cell Function in Recent Onset Type 1 Diabetes
Clinical and Experimental Immunology
2016

Identification of Tissue-Specific Cell Death Using Methylation Patterns of Circulating DNa
Proceedings of the National Academy of Sciences
2016

Growth and Risk for Islet Autoimmunity and Progression to Type 1 Diabetes in Early Childhood: the Environmental Determinants of Diabetes in the Young Study
Diabetes
2016

Screening for T1D Risk to Reduce Dka Is Not Economically Viable
Pediatric Diabetes
2015

Prevalence of Detectable C-Peptide According To Age At Diagnosis and Duration of Type 1 Diabetes
Diabetes Care
2015

Anti-Thymocyte Globulin/G-Csf Treatment Preserves Beta Cell Function in Patients With Established Type 1 Diabetes
The Journal of clinical investigation
2015

Effect of a Single Autologous Cord Blood Infusion On Beta-Cell and Immune Function in Children With New Onset Type 1 Diabetes: a Non-Randomized, Controlled Trial
Pediatric Diabetes
2014

Children Followed in the Teddy Study Are Diagnosed With Type 1 Diabetes At An Early Stage of Disease
Pediatric Diabetes
2014

A Contrast Between Children and Adolescents With Excellent and Poor Control: the T1D Exchange Clinic Registry Experience
Pediatric Diabetes
2014

The Autoimmune Disease-Associated Snp Rs917997 of Il18Rap Controls Ifn Gamma Production By Pbmc
Journal of Autoimmunity
2013

Evidence of a Strong Association Between Frequency of Self-Monitoring of Blood Glucose and Hemoglobin A(1C) Levels in T1D Exchange Clinic Registry Participants
Diabetes Care
2013

Diabetic Ketoacidosis At Diabetes Onset: Still An All Too Common Threat in Youth
Journal of Pediatrics
2013

Autologous Umbilical Cord Blood Infusion Followed By Oral Docosahexaenoic Acid and Vitamin D Supplementation for C-Peptide Preservation in Children With Type 1 Diabetes
Biology of Blood and Marrow Transplantation
2013

Update On Global Intervention Studies in Type 1 Diabetes
Endocrinology and Metabolism Clinics of North America
2012

Type 1 Diabetes: Current Concepts in Epidemiology, Pathophysiology, Clinical Care, and Research
Current Problems in Pediatric and Adolescent Health Care
2012

Through the Fog: Recent Clinical Trials To Preserve Beta-Cell Function in Type 1 Diabetes
Diabetes
2012

Tanner Stage 4 Breast Development in Adults: Forensic Implications
Pediatrics
2012

Characteristics of Thawed Autologous Umbilical Cord Blood
Transfusion
2012

Use of a Precious Resource: Parental Decision Making About Using Autologous Umbilical Cord Blood in Studies Involving Young Children With Type 1 Diabetes
Contemporary Clinical Trials
2011

Reduced Serum Vitamin D-Binding Protein Levels Are Associated With Type 1 Diabetes
Diabetes
2011

Reduced Prevalence of Diabetic Ketoacidosis At Diagnosis of Type 1 Diabetes in Young Children Participating in Longitudinal Follow-Up
Diabetes Care
2011

Progressive Erosion of Beta-Cell Function Precedes the Onset of Hyperglycemia in the Nod Mouse Model of Type 1 Diabetes
Diabetes
2011

Loss of Intra-Islet Cd20 Expression May Complicate Efficacy of B-Cell-Directed Type 1 Diabetes Therapies
Diabetes
2011

Islet Autoantibody Seroconversion in the Dpt-1 Study Justification for Repeat Screening Throughout Childhood
Diabetes Care
2011

Development of Autoantibodies in the Trialnet Natural History Study
Diabetes Care
2011

Autologous Umbilical Cord Blood Transfusion in Young Children With Type 1 Diabetes Fails To Preserve C-Peptide
Diabetes Care
2011

Type I diabetes. Preface.
Endocrinology and Metabolism Clinics of North America
2010

Intradermal Alpha 1-Antitrypsin Therapy Avoids Fatal Anaphylaxis, Prevents Type 1 Diabetes and Reverses Hyperglycaemia in the Nod Mouse Model of the Disease
Diabetologia
2010

Exendin-4 Treatment of Nonobese Diabetic Mice Increases Beta-Cell Proliferation and Fractional Insulin Reactive Area
Journal of Diabetes and Its Complications
2010

Efforts To Prevent and Halt Autoimmune Beta Cell Destruction
Endocrinology and Metabolism Clinics of North America
2010

Coronary Artery Disease in Youth: Present Markers, Future Hope?
Journal of Pediatrics
2010

Arterial Stiffness, Lipoprotein Particle Size, and Lipoprotein Particle Concentration in Children With Type 1 Diabetes
Journal of Pediatric Endocrinology & Metabolism
2010

Vitamin D Levels in Subjets With and Without Type 1 Diabetes Residing in a Solar Rich Environment
Diabetes Care
2009

Vascular Dysfunction in Glycogen Storage Disease Type I
Journal of Pediatrics
2009

The road not taken: a path to curing type 1 diabetes?
European Journal of Immunology
2009

Serum Monocyte Chemoattractant Protein-1 Concentrations Associate With Diabetes Status But Not Arterial Stiffness in Children With Type 1 Diabetes
Diabetes Care
2009

Seroconversion in the Dpt-1 Study: Evidence of Triggering of Autoimmune Process At Different Ages

2009

Pediatric Atorvastatin in Diabetes Trial (Padit): a Pilot Study To Determine the Effect of Atorvastatin On Arterial Stiffness and Endothelial Function in Children With Type 1 Diabetes Mellitus
Journal of Pediatric Endocrinology & Metabolism
2009

Pediatric Atorvastatin in Diabetes Trial (Padit): a Pilot Study To Determine the Effect of Atorvastatin On Arterial Stiffness and Endothelial Function in Children With Type 1 Diabetes Mellitus
Journal of Pediatric Endocrinology & Metabolism
2009

In Pursuit of Lower A1C
Journal of Pediatrics
2009

Immune Depletion With Cellular Mobilization Imparts Immunoregulation and Reverses Autoimmune Diabetes in Nonobese Diabetic Mice
Diabetes
2009

Autologous Umbilical Cord Blood Transfusion in Very Young Children With Type 1 Diabetes
Diabetes Care
2009

Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation in Newly Diagnosed Type 1 Diabetes Mellitus
Jama-Journal of the American Medical Association
2009

Atorvastatin Differentially Affects Serum and Leukocyte Mcp-1 Concentrations With No Contribution From Nos3 Gene Variation.
Clinical Pharmacology & Therapeutics
2009

What'S in a Name? Thyroid Autoimmunity in Obese Patients With T1D
Pediatric Diabetes
2008

Type 1 Diabetes Associated With Acquired Generalized Lipodystrophy and Insulin Resistance: the Effect of Long-Term Leptin Therapy
The Journal of clinical endocrinology and metabolism
2008

Exendin-4 Therapy in Nod Mice With New-Onset Diabetes Increases Regulatory T Cell Frequency
Annals of the New York Academy of Sciences
2008

Cytokines and Type 1 Diabetes Complications: Casual Or Causal Association?
Pediatric Diabetes
2008

Characteristics and Cell Compostion of Privately Banked Autologous Umbilical Cord Blood (Ucb) Units Utilized for Autologous Ucb Infusion in Children With Type I Diabetes
Biology of Blood and Marrow Transplantation
2008

Autologous Umbilical Cord Blood Infusion for Type 1 Diabetes
Experimental Hematology
2008

Type 1 diabetes intervention trials 2007: where are we and where are we going?
Current Opinion in Endocrinology & Diabetes
2007

Peripheral artery tonometry demonstrates altered endothelial function in children with type 1 diabetes.
Pediatric Diabetes
2007

No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
Diabetes
2007

Endocrine complications of childhood cancer therapy: evaluation and management.
Pediatric endocrinology reviews : PER
2007

Adverse impact of temperature and humidity on blood glucose monitoring reliability: a pilot study.
Diabetes Technology & Therapeutics
2007

Serum superoxide dismutase activity and nitric oxide do not correlate with arterial stiffness in children with type 1 diabetes mellitus.
Journal of Pediatric Endocrinology & Metabolism
2006

Arterial thrombosis resulting in amputation in a child with poorly controlled type 1 diabetes and heterozygous Factor V Leiden mutation.
Pediatric Diabetes
2006

Radial artery tonometry demonstrates arterial stiffness in children with type 1 diabetes.
Diabetes Care
2004

Predictors of control of diabetes: monitoring may be the key
Journal of Pediatrics
2004

Blood lymphocyte chimerism associated with IVF and monochorionic dizygous twinning: case report.
Human reproduction (Oxford, England)
2004

Research Interests

Dr. Haller's research focuses on predicting, preventing, and ultimately reversing type 1 diabetes through his participation in numerous clinical trials utilizing immunotherapies. Dr. Haller serves as the Principal Investigator for the University of Florida TrialNet Clinical Center, Chair of the TEDDY Clinical Implementation Committee, and PI of the UF/Stanford ECHO Collaborative. Dr. Haller also leads and participates in technology studies seeking to improve the lives of people living with diabetes through the use of pumps, continuous glucose monitors, and systems that automate insulin delivery.