To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis
- Investigator
- Torge Rempe
- Status
- Accepting Candidates
- Ages
- 18 Years - 55 Years
- Sexes
- All
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The UF Multiple Sclerosis Division was established on the philosophy that integrated, interdisciplinary care is the most effective approach for patients with MS. Our one-of-a-kind clinical research organization was formed in order to address a void in patient care, research, outreach and education regarding multiple sclerosis in Florida.
According to the National MS Society, the state of Florida is home to more than 20,000 MS patients. Our patients have access to highly coordinated, competent and accessible care through our division. While our patients enjoy outstanding clinical care, they also have an open door to the latest clinical/translational research studies. Patients also have a chance to volunteer and assist in future investigator-initiated research studies.
Our goal is for our patients to live a next-to-normal life with little function loss. Most people with MS are very active and have long, fulfilling lives.
Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. In MS, the immune system attacks and damages the protective covering (called myelin) surrounding nerve fibers in the central nervous system. This damage can disrupt communication between the brain and other parts of the body, leading to a range of symptoms that can vary in severity and duration.
Some common symptoms of MS include:
The exact cause of MS is unknown, but it is believed to be a combination of genetic and environmental factors. It is more common in people of Northern European descent and is more prevalent in women than men. MS commonly affects people aged 20-40.
Diagnosing MS can be challenging because the symptoms can vary widely from person to person and can be similar to those of other conditions. To diagnose MS, a healthcare provider will typically perform a physical exam, review the patient's medical history, and order various tests, such as:
There is no one-size-fits-all treatment for MS, as the disease can affect each person differently. At UF Health, our team of experts will work with you to create a personalized treatment plan that is tailored to your specific needs and goals.
Our neurological specialists will consult with you in the comfort of your own home using your myuflhealth account. Secure video conferencing protects your privacy and saves you time and money traveling to our office. Telehealth appointments are reimbursable through Florida's Medicaid and Medicare programs. Please contact us to set a telehealth appointment at (352) 294-5400.
UF Health research scientists make medicine better every day. They discover new ways to help people by running clinical trials. When you join a clinical trial, you can get advanced medical care. Sometimes years before it's available everywhere. You can also help make medicine better for everyone else. If you'd like to learn more about clinical trials, visit our clinical trials page. Or click one of the links below:
To compare the efficacy and safety of remibrutinib versus teriflunomide in patients with relapsing multiple sclerosis
FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) target the relapsing phase of MS but have minimal impact once the progressive phase has begun. It is unclear if, in the relapsing phase, there is an advantage of early…
Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary Objectives: To evaluate efficacy of SAR442168 compared to placebo on clinical…
Our community and patient programs provide great value to patients, families and loved ones. People can find support, educational materials, expert consultants and more. In most instances, these programs are offered free of charge.
Designed to help people with a diagnosis of MS, Parkinson’s disease (PD), or other similar neurological movement disorders improve physical well-being, social interaction and creative expression.
Children with serious illnesses can enjoy a camp experience in a safe, medically sound environment.
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More than 900,000 adults in the United States are living with multiple sclerosis, according to the National Multiple Sclerosis Society. The multiple sclerosis…
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Living with multiple sclerosis can be cruel: watching your body decline for decades, knowing your nerves are under attack, increasingly losing your ability to function. Commonly abbreviated M-S,...