Colorectal cancer ranks as the second leading cause of cancer-related deaths in the United States. Referred to as a “silent killer” due to its lack of…
A colonoscopy is an exam that views the inside of the colon (large intestine) and rectum, using a tool called a colonoscope.
The colonoscope has a small camera attached to a flexible tube that can reach the length of the colon.
Patient Education Video: Colon cancer screening
Colon cancer - colonoscopy; Colorectal cancer - colonoscopy; Colonoscopy - screening; Colon polyps - colonoscopy; Ulcerative colitis - colonoscopy; Crohn disease - colonoscopy; Diverticulitis - colonoscopy; Diarrhea - colonoscopy; Anemia - colonoscopy; Blood in stool - colonoscopy
How the Test is Performed
Colonoscopy is done most often in a procedure room at your doctor's office. It can also be done in the outpatient department of a hospital or medical center.
- You will be asked to change out of your street clothes and wear a hospital gown for the procedure.
- You will likely be given medicine into a vein (IV) to help you relax. You should not feel any pain. You may be awake during the test and may even be able to speak. You will probably not remember anything.
- You lie on your left side with your knees drawn up toward your chest.
- The scope is gently inserted through the anus. It is carefully moved into the beginning of the large intestine. The scope is slowly advanced as far as the lowest part of the small intestine.
- Air is inserted through the scope to provide a better view. Suction may be used to remove fluid or stool.
- The doctor gets a better view as the scope is moved back out. So, a more careful exam is done while the scope is being pulled back.
- Tissue samples (biopsy) or polyps may be removed using tiny tools inserted through the scope. Photos may be taken using the camera at the end of the scope. If needed, procedures, such as laser therapy, are also done.
How to Prepare for the Test
Your bowel needs to be completely empty and clean for the exam. A problem in your large intestine that needs to be treated may be missed if your intestines are not cleaned out.
Your health care provider will give you the steps for cleansing your bowel. This is called bowel preparation. Steps may include:
- Using enemas
- Not eating solid foods for 1 to 3 days before the test
- Taking laxatives
You need to drink plenty of clear liquids for 1 to 3 days before the test. Examples of clear liquids are:
- Clear coffee or tea
- Fat-free bouillon or broth
- Sports drinks without added color
- Strained fruit juices
You will likely be told to stop taking aspirin, ibuprofen, naproxen, or other blood-thinning medicines for several days before the test. Keep taking your other medicines unless your doctor tells you otherwise.
You will need to stop taking iron pills or liquids a few days before the test, unless your provider tells you it is OK to continue. Iron can make your stool dark black. This makes it harder for the doctor to view inside your bowel.
How the Test will Feel
The medicines will make you sleepy so that you may not feel any discomfort or have any memory of the test.
You may feel pressure as the scope moves inside. You may feel brief cramping and gas pains as air is inserted or the scope advances. Passing gas is necessary and should be expected.
After the exam, you may have mild abdominal cramping and pass a lot of gas. You may also feel bloated and sick to your stomach. These feelings will soon go away.
You should be able to go home about one hour after the test. You must plan to have someone take you home after the test because you will be woozy and unable to drive. The providers will not let you leave until someone arrives to help you.
When you are home, follow instructions on recovering from the procedure. These may include:
- Drink plenty of liquids. Eat a healthy meal to restore your energy.
- You should be able to return to your regular activities the next day.
- Avoid driving, operating machinery, drinking alcohol, and making important decisions for at least 24 hours after the test.
Why the Test is Performed
Colonoscopy may be done for the following reasons:
- Abdominal pain, changes in bowel movements, or weight loss
- Abnormal changes (polyps) found on sigmoidoscopy or x-ray tests (CT scan or barium enema)
- Anemia due to low iron (usually when no other cause has been found)
- Blood in the stool, or black, tarry stools
- Follow-up of a past finding, such as polyps or colon cancer
- Inflammatory bowel disease (ulcerative colitis and Crohn disease)
- Screening for colorectal cancer
Normal findings are healthy intestinal tissues.
What Abnormal Results Mean
Abnormal test results may mean any of the following:
- Abnormal pouches on the lining of the intestines, called diverticulosis
- Areas of bleeding
- Cancer in the colon or rectum
- Colitis (a swollen and inflamed intestine) due to Crohn disease, ulcerative colitis, infection, or lack of blood flow
- Small growths called polyps on the lining of your colon (which can be removed through the colonoscope during the exam)
Risks of colonoscopy may include any of the following:
- Heavy or ongoing bleeding from biopsy or removal of polyps
- Hole or tear in the wall of the colon that requires surgery to repair
- Infection needing antibiotic therapy (very rare)
- Reaction to the medicine you are given to relax, causing breathing problems or low blood pressure
Garber JJ, Chung DC, eds. Colonic polyps and polyposis syndromes. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 11th ed. Philadelphia, PA: Elsevier; 2021:chap 126.
Lawler M, Johnson B, Van Schaeybroeck S, et al. Colorectal cancer. In: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020:chap 74.
National Cancer Institute. Colorectal Cancer Prevention (PDQ) - Health Professional Version. www.cancer.gov/types/colorectal/hp/colorectal-prevention-pdq. Updated April 21, 2022. Accessed May 27, 2022.
Rex DK, Boland CR, Dominitz JA, et al. Colorectal cancer screening: recommendations for physicians and patients from the U.S. Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol. 2017;112(7):1016-1030. PMID: 28555630 pubmed.ncbi.nlm.nih.gov/28555630/.
US Preventive Services Task Force website. Final recommendation statement. Colorectal cancer: screening. www.uspreventiveservicestaskforce.org/uspstf/recommendation/colorectal-cancer-screening. Published May 18, 2021. Accessed May 27, 2022.
Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA Cancer J Clin. 2018;68(4):250-281. PMID: 29846947 pubmed.ncbi.nlm.nih.gov/29846947/.
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