Clinical trials

This is a multicenter, randomized, double-blind, parallel, placebo-controlled Phase 3, 2-arm study for treatment. The purpose of this study is to measure change in glycemic control and prandial insulin independency over 52 weeks with teplizumab…

Investigator

Michael J Haller

Ages

1 Year - 25 Years

Sexes

All

This is a 78-week single arm, multi-center, Phase 1 study to evaluate the safety, tolerability, cellular kinetics, and biomarker changes in C-peptide over time of GNTI-122, an investigational cell therapy manufactured from a participant's own blood…

Investigator

Brittany S Bruggeman

Ages

18 Years - 45 Years

Sexes

All

This is a Phase 2b, investigator* and participant-blinded, placebo-controlled, parallel-arm study to evaluate the efficacy, safety and tolerability of SAB 142 in patients with Stage 3 New Onset of Type 1 Diabetes (NOT1D).

Investigator

Laura Jacobsen

Ages

5 Years - 40 Years

Sexes

All

The goal of the study to understand the effects of weight loss and improvements in diabetes following bariatric surgery on brain function and thinking. This study will also examine whether non-invasive transcutaneous vagal nerve stimulation (tVNS)…

Ages

20 Years - 75 Years

Sexes

All